Daple is a novel non-receptor GEF required for trimeric G protein activation in Wnt signaling N Aznar, KK Midde, Y Dunkel, I Lopez-Sanchez, Y Pavlova, A Marivin, ... Elife 4, e07091, 2015 | 124 | 2015 |
Revealing the activity of trimeric G-proteins in live cells with a versatile biosensor design M Maziarz, JC Park, A Leyme, A Marivin, A Garcia-Lopez, PP Patel, ... Cell 182 (3), 770-785. e16, 2020 | 60 | 2020 |
Cellular inhibitor of apoptosis protein-1 (cIAP1) can regulate E2F1 transcription factor-mediated control of cyclin transcription J Cartier, J Berthelet, A Marivin, S Gemble, V Edmond, S Plenchette, ... Journal of Biological Chemistry 286 (30), 26406-26417, 2011 | 51 | 2011 |
Molecular mechanism of Gαi activation by non-GPCR proteins with a Gα-binding and activating motif AI de Opakua, K Parag-Sharma, V DiGiacomo, N Merino, A Leyme, ... Nature communications 8 (1), 15163, 2017 | 46 | 2017 |
Integrins activate trimeric G proteins via the nonreceptor protein GIV/Girdin A Leyme, A Marivin, L Perez-Gutierrez, LT Nguyen, M Garcia-Marcos Journal of Cell Biology 210 (7), 1165-1184, 2015 | 46 | 2015 |
When heterotrimeric G proteins are not activated by G protein-coupled receptors: structural insights and evolutionary conservation V DiGiacomo, A Marivin, M Garcia-Marcos Biochemistry 57 (3), 255-257, 2018 | 35 | 2018 |
The inhibitor of apoptosis (IAPs) in adaptive response to cellular stress A Marivin, J Berthelet, S Plenchette, L Dubrez Cells 1 (4), 711-737, 2012 | 33 | 2012 |
Dominant-negative Gα subunits are a mechanism of dysregulated heterotrimeric G protein signaling in human disease A Marivin, A Leyme, K Parag-Sharma, V DiGiacomo, AY Cheung, ... Science signaling 9 (423), ra37-ra37, 2016 | 32 | 2016 |
Evolutionary conservation of a GPCR-independent mechanism of trimeric G protein activation BD Coleman, A Marivin, K Parag-Sharma, V DiGiacomo, S Kim, ... Molecular biology and evolution 33 (3), 820-837, 2016 | 32 | 2016 |
Atypical activation of the G protein Gαq by the oncogenic mutation Q209P M Maziarz, A Leyme, A Marivin, A Luebbers, PP Patel, Z Chen, ... Journal of Biological Chemistry 293 (51), 19586-19599, 2018 | 31 | 2018 |
cIAP1 regulates TNF-mediated cdc42 activation and filopodia formation A Marivin, J Berthelet, J Cartier, C Paul, S Gemble, A Morizot, W Boireau, ... Oncogene 33 (48), 5534-5545, 2014 | 27 | 2014 |
Specific inhibition of GPCR-independent G protein signaling by a rationally engineered protein A Leyme, A Marivin, M Maziarz, V DiGiacomo, MP Papakonstantinou, ... Proceedings of the National Academy of Sciences 114 (48), E10319-E10328, 2017 | 24 | 2017 |
GIV/Girdin (Gα-interacting, vesicle-associated protein/Girdin) creates a positive feedback loop that potentiates outside-in integrin signaling in cancer cells A Leyme, A Marivin, M Garcia-Marcos Journal of Biological Chemistry 291 (15), 8269-8282, 2016 | 23 | 2016 |
GPCR-independent activation of G proteins promotes apical cell constriction in vivo A Marivin, V Morozova, I Walawalkar, A Leyme, DA Kretov, D Cifuentes, ... Journal of cell biology 218 (5), 1743-1763, 2019 | 20 | 2019 |
DAPLE and MPDZ bind to each other and cooperate to promote apical cell constriction A Marivin, M Garcia-Marcos Molecular biology of the cell 30 (16), 1900-1910, 2019 | 19 | 2019 |
Membrane recruitment of the non-receptor protein GIV/girdin (Gα-interacting, vesicle-associated protein/girdin) is sufficient for activating heterotrimeric G protein signaling K Parag-Sharma, A Leyme, V DiGiacomo, A Marivin, S Broselid, ... Journal of Biological Chemistry 291 (53), 27098-27111, 2016 | 19 | 2016 |
Optogenetic activation of heterotrimeric G-proteins by LOV2GIVe, a rationally engineered modular protein M Garcia-Marcos, K Parag-Sharma, A Marivin, M Maziarz, A Luebbers, ... Elife 9, e60155, 2020 | 16 | 2020 |
Different biochemical properties explain why two equivalent Gα subunit mutants cause unrelated diseases A Leyme, A Marivin, J Casler, LT Nguyen, M Garcia-Marcos Journal of Biological Chemistry 289 (32), 21818-21827, 2014 | 15 | 2014 |
IAPs: a central element in the NF-κB activating signaling pathway J Cartier, A Marivin, J Berthelet, L Dubrez Medecine Sciences: M/S 28 (1), 69-75, 2012 | 14 | 2012 |
DAPLE protein inhibits nucleotide exchange on Gαs and Gαq via the same motif that activates Gαi A Marivin, M Maziarz, J Zhao, V DiGiacomo, IO Calvo, EA Mann, J Ear, ... Journal of Biological Chemistry 295 (8), 2270-2284, 2020 | 12 | 2020 |