| Anti-phospholipid antibodies in COVID-19 are different from those detectable in the anti-phospholipid syndrome MO Borghi, A Beltagy, E Garrafa, D Curreli, G Cecchini, C Bodio, C Grossi, ... Frontiers in immunology 11, 584241, 2020 | 172 | 2020 |
| Essential role of conformational selection in ligand binding AD Vogt, N Pozzi, Z Chen, E Di Cera Biophysical chemistry 186, 13-21, 2014 | 134 | 2014 |
| Conformational selection in trypsin-like proteases N Pozzi, AD Vogt, DW Gohara, E Di Cera Current Opinion in Structural Biology, 2012 | 94 | 2012 |
| Antibodies to Domain I of β2Glycoprotein I are in close relation to patients risk categories in Antiphospholipid Syndrome (APS) A Banzato, N Pozzi, R Frasson, V De Filippis, A Ruffatti, E Bison, ... Thrombosis research 128 (6), 583-586, 2011 | 88 | 2011 |
| Histone H4 promotes prothrombin autoactivation S Barranco-Medina, N Pozzi, AD Vogt, E Di Cera Journal of Biological Chemistry 288 (50), 35749-35757, 2013 | 85 | 2013 |
| Formation of methionine sulfoxide by peroxynitrite at position 1606 of von Willebrand factor inhibits its cleavage by ADAMTS-13: A new prothrombotic mechanism in diseases … S Lancellotti, V De Filippis, N Pozzi, F Peyvandi, R Palla, B Rocca, ... Free radical biology and medicine 48 (3), 446-456, 2010 | 69 | 2010 |
| Lupus anticoagulant identifies two distinct groups of patients with different antibody patterns V Pengo, T Del Ross, A Ruffatti, E Bison, MG Cattini, E Pontara, S Testa, ... Thrombosis research 172, 172-178, 2018 | 59 | 2018 |
| Crystal structure of prothrombin reveals conformational flexibility and mechanism of activation N Pozzi, Z Chen, DW Gohara, W Niu, T Heyduk, E Di Cera Journal of Biological Chemistry 288 (31), 22734-22744, 2013 | 59 | 2013 |
| Crystallographic and kinetic evidence of allostery in a trypsin-like protease W Niu, Z Chen, PS Gandhi, AD Vogt, N Pozzi, LA Pelc, F Zapata, ... Biochemistry 50 (29), 6301-6307, 2011 | 50 | 2011 |
| Fibrinogen-elongated γ chain inhibits thrombin-induced platelet response, hindering the interaction with different receptors S Lancellotti, S Rutella, V De Filippis, N Pozzi, B Rocca, R De Cristofaro Journal of Biological Chemistry 283 (44), 30193-30204, 2008 | 50 | 2008 |
| The linker connecting the two kringles plays a key role in prothrombin activation N Pozzi, Z Chen, LA Pelc, DB Shropshire, E Di Cera Proceedings of the National Academy of Sciences 111 (21), 7630-7635, 2014 | 49 | 2014 |
| Multiple-organ complement deposition on vascular endothelium in COVID-19 patients P Macor, P Durigutto, A Mangogna, R Bussani, L De Maso, S D’Errico, ... Biomedicines 9 (8), 1003, 2021 | 45 | 2021 |
| Crystal structures of prethrombin-2 reveal alternative conformations under identical solution conditions and the mechanism of zymogen activation N Pozzi, Z Chen, F Zapata, LA Pelc, S Barranco-Medina, E Di Cera Biochemistry 50 (47), 10195-10202, 2011 | 45 | 2011 |
| Structure of prothrombin in the closed form reveals new details on the mechanism of activation M Chinnaraj, Z Chen, LA Pelc, Z Grese, D Bystranowska, E Di Cera, ... Scientific Reports 8 (1), 2945, 2018 | 43 | 2018 |
| Apolipoprotein L1 confers pH-switchable ion permeability to phospholipid vesicles J Bruno, N Pozzi, J Oliva, JC Edwards Journal of Biological Chemistry 292 (44), 18344-18353, 2017 | 43 | 2017 |
| Autoactivation of thrombin precursors N Pozzi, Z Chen, F Zapata, W Niu, S Barranco-Medina, LA Pelc, E Di Cera Journal of Biological Chemistry 288 (16), 11601-11610, 2013 | 43 | 2013 |
| Structure of coagulation factor II: molecular mechanism of thrombin generation and development of next-generation anticoagulants M Chinnaraj, W Planer, N Pozzi Frontiers in Medicine 5, 281, 2018 | 42 | 2018 |
| β2-Glycoprotein I binds to thrombin and selectively inhibits the enzyme procoagulant functions N Pozzi, L Acquasaliente, R Frasson, A Cristiani, S Moro, A Banzato, ... Journal of Thrombosis and Haemostasis 11 (6), 1093-1102, 2013 | 38 | 2013 |
| Redesigning allosteric activation in an enzyme S Rana, N Pozzi, LA Pelc, E Di Cera Proceedings of the National Academy of Sciences 108 (13), 5221-5225, 2011 | 36 | 2011 |
| How the linker connecting the two kringles influences activation and conformational plasticity of prothrombin N Pozzi, Z Chen, E Di Cera Journal of Biological Chemistry 291 (12), 6071-6082, 2016 | 35 | 2016 |
Austin VogtPostdoctoral Fellow, University of PennsylvaniaVerified email at mail.med.upenn.edu
