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Virginia Lee
Virginia Lee
Professor of Pathology and Laboratory Medicine, University of Pennsylvania
Verified email at upenn.edu - Homepage
Title
Cited by
Cited by
Year
α-Synuclein in Lewy bodies
MG Spillantini, ML Schmidt, VMY Lee, JQ Trojanowski, R Jakes, ...
Nature 388 (6645), 839-840, 1997
98761997
Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium
IG McKeith, DW Dickson, J Lowe, M Emre, JT O'brien, H Feldman, ...
Neurology 65 (12), 1863-1872, 2005
8927*2005
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
M Neumann, DM Sampathu, LK Kwong, AC Truax, MC Micsenyi, TT Chou, ...
Science 314 (5796), 130-133, 2006
71622006
Neurodegenerative tauopathies
VMY Lee, M Goedert, JQ Trojanowski
Annual review of neuroscience 24 (1), 1121-1159, 2001
34572001
Tau-mediated neurodegeneration in Alzheimer's disease and related disorders
C Ballatore, VMY Lee, JQ Trojanowski
Nature reviews neuroscience 8 (9), 663-672, 2007
27252007
Pathological α-synuclein transmission initiates Parkinson-like neurodegeneration in nontransgenic mice
KC Luk, V Kehm, J Carroll, B Zhang, P O’Brien, JQ Trojanowski, VMY Lee
Science 338 (6109), 949-953, 2012
26122012
Cerebrospinal fluid biomarker signature in Alzheimer's disease neuroimaging initiative subjects
LM Shaw, H Vanderstichele, M Knapik‐Czajka, CM Clark, PS Aisen, ...
Annals of neurology 65 (4), 403-413, 2009
23202009
Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model
Y Yoshiyama, M Higuchi, B Zhang, SM Huang, N Iwata, TC Saido, ...
Neuron 53 (3), 337-351, 2007
22152007
Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.
M Baba, S Nakajo, PH Tu, T Tomita, K Nakaya, VM Lee, JQ Trojanowski, ...
The American journal of pathology 152 (4), 879, 1998
21271998
Oxidative damage linked to neurodegeneration by selective α-synuclein nitration in synucleinopathy lesions
BI Giasson, JE Duda, IVJ Murray, Q Chen, JM Souza, HI Hurtig, ...
Science 290 (5493), 985-989, 2000
19942000
A68: a major subunit of paired helical filaments and derivatized forms of normal Tau
VMY Lee, BJ Balin, L Otvos Jr, JQ Trojanowski
Science 251 (4994), 675-678, 1991
18201991
Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death
LA Volpicelli-Daley, KC Luk, TP Patel, SA Tanik, DM Riddle, A Stieber, ...
Neuron 72 (1), 57-71, 2011
16852011
Chaperone suppression of α-synuclein toxicity in a Drosophila model for Parkinson's disease
PK Auluck, HYE Chan, JQ Trojanowski, VMY Lee, NM Bonini
Science 295 (5556), 865-868, 2002
16302002
GSK-3α regulates production of Alzheimer's disease amyloid-β peptides
CJ Phiel, CA Wilson, VMY Lee, PS Klein
Nature 423 (6938), 435-439, 2003
16052003
Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS
AC Elden, HJ Kim, MP Hart, AS Chen-Plotkin, BS Johnson, X Fang, ...
Nature 466 (7310), 1069-1075, 2010
14492010
Neuronal α-synucleinopathy with severe movement disorder in mice expressing A53T human α-synuclein
BI Giasson, JE Duda, SM Quinn, B Zhang, JQ Trojanowski, VMY Lee
Neuron 34 (4), 521-533, 2002
14462002
Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration
NJ Cairns, EH Bigio, IRA Mackenzie, M Neumann, VMY Lee, ...
Acta neuropathologica 114, 5-22, 2007
14452007
A hydrophobic stretch of 12 amino acid residues in the middle of α-synuclein is essential for filament assembly
BI Giasson, IVJ Murray, JQ Trojanowski, VMY Lee
Journal of Biological Chemistry 276 (4), 2380-2386, 2001
13592001
Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17
M Hong, V Zhukareva, V Vogelsberg-Ragaglia, Z Wszolek, L Reed, ...
Science 282 (5395), 1914-1917, 1998
12241998
Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
KC Luk, VM Kehm, B Zhang, P O’Brien, JQ Trojanowski, VMY Lee
Journal of Experimental Medicine 209 (5), 975-986, 2012
12222012
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