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Srijana Pokhrel
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Counteracting H3K4 methylation modulators Set1 and Jhd2 co-regulate chromatin dynamics and gene transcription
S Ramakrishnan, S Pokhrel, S Palani, C Pflueger, TJ Parnell, BR Cairns, ...
Nature communications 7 (1), 11949, 2016
522016
Innate sex bias of Staphylococcus aureus skin infection is driven by α-hemolysin
MJ Castleman, S Pokhrel, KD Triplett, DF Kusewitt, BO Elmore, JA Joyner, ...
The Journal of Immunology 200 (2), 657-668, 2018
392018
Generation of a Stable Plasmid for In Vitro and In Vivo Studies of Staphylococcus Species
CN Krute, KL Krausz, MA Markiewicz, JA Joyner, S Pokhrel, PR Hall, ...
Applied and environmental microbiology 82 (23), 6859-6869, 2016
252016
GPER activation protects against epithelial barrier disruption by Staphylococcusaureus α-toxin
KD Triplett, S Pokhrel, MJ Castleman, SM Daly, BO Elmore, JA Joyner, ...
Scientific Reports 9 (1), 1343, 2019
212019
Interaction of the Jhd2 histone H3 Lys-4 demethylase with chromatin is controlled by histone H2A surfaces and restricted by H2B ubiquitination
F Huang, S Ramakrishnan, S Pokhrel, C Pflueger, TJ Parnell, MM Kasten, ...
Journal of Biological Chemistry 290 (48), 28760-28777, 2015
212015
VLP-based vaccine induces immune control of Staphylococcus aureus virulence regulation
SM Daly, JA Joyner, KD Triplett, BO Elmore, S Pokhrel, KM Frietze, ...
Scientific Reports 7 (1), 637, 2017
142017
Structure and functional determinants of Rad6–Bre1 subunits in the histone H2B ubiquitin-conjugating complex
PK Shukla, JE Bissell, S Kumar, S Pokhrel, S Palani, KS Radmall, O Obidi, ...
Nucleic Acids Research 51 (5), 2117-2136, 2023
122023
Aiolos represses CD4+ T cell cytotoxic programming via reciprocal regulation of TFH transcription factors and IL-2 sensitivity
KA Read, DM Jones, S Pokhrel, EDS Hales, A Varkey, JA Tuazon, ...
Nature Communications 14 (1), 1652, 2023
82023
Vaccination with VLPs Presenting a Linear Neutralizing Domain of S. aureus Hla Elicits Protective Immunity
JA Joyner, SM Daly, J Peabody, KD Triplett, S Pokhrel, BO Elmore, ...
Toxins 12 (7), 450, 2020
82020
Complement receptor 3 contributes to the sexual dimorphism in neutrophil killing of Staphylococcus aureus
S Pokhrel, KD Triplett, SM Daly, JA Joyner, G Sharma, HJ Hathaway, ...
The Journal of Immunology 205 (6), 1593-1600, 2020
62020
Counteracting H3K4 methylation modulators Set1 and Jhd2 co-regulate chromatin dynamics and gene transcription. Nat. Commun. 7: 11949
S Ramakrishnan, S Pokhrel, S Palani, C Pflueger, TJ Parnell, BR Cairns, ...
J Clin Oncol 23, 9105-9112, 2016
62016
Eos Promotes TH2 Differentiation by Interacting with and Propagating the Activity of STAT5
JA Tuazon, KA Read, BK Sreekumar, JE Roettger, MJ Yaeger, S Varikuti, ...
The Journal of Immunology 211 (3), 365-376, 2023
12023
Cytotoxic Programming of CD4+ T Cells Is Regulated by Opposing Actions of the Related Transcription Factors Eos and Aiolos
DM Jones, JA Tuazon, KA Read, MR Leonard, S Pokhrel, BK Sreekumar, ...
The Journal of Immunology, 2024
2024
The Ikaros zinc finger transcription factor Aiolos as a novel regulator of T cell migration.
M Leonard, KA Read, DM Jones, S Pokhrel, RT Warren, KJ Oestreich
The Journal of Immunology 210 (1_Supplement), 243.21-243.21, 2023
2023
Aiolos restrains acquisition of a cytotoxic program by CD4+ T cells
DM Jones, KA Read, S Pokhrel, J Tuazon, MR Leonard, M Salem, ...
The Journal of Immunology 210 (1_Supplement), 64.04-64.04, 2023
2023
Aiolos modulates the TFH and CD4-CTL differentiation programs via reciprocal regulation of the Zfp831/TCF-1/Bcl-6 axis and CD25
KA Read, DM Jones, S Pokhrel, EDS Hales, A Varkey, JA Tuazon, ...
bioRxiv, 2022.05. 18.492485, 2022
2022
Aiolos supports TFH cell differentiation by antagonizing the IL-2/STAT5 signaling pathway
K Read, S Pokhrel, DM Jones, A Saadey, C Eisele, RT Warren, P Collins, ...
The Journal of Immunology 208 (1_Supplement), 112.20-112.20, 2022
2022
Aiolos restrains the acquisition of cytotoxic features by CD4+ T cells
DM Jones, KA Read, S Pokhrel, E Hales, C Eisele, RT Warren, P Collins, ...
The Journal of Immunology 208 (1_Supplement), 166.03-166.03, 2022
2022
Eos regulates IL-7 signaling and central memory T cell differentiation
S Pokhrel, KA Read, DM Jones, MD Powell, RT Warren, KJ Oestreich
The Journal of Immunology 208 (1_Supplement), 57.04-57.04, 2022
2022
Eos differentially regulates Th1 versus Tfh differentiation through feed-forward propagation of the IL-2/STAT5 signaling pathway
K Read, B Sreekumar, MD Powell, DM Jones, S Pokhrel, A Saadey, ...
The Journal of Immunology 206 (1_Supplement), 53.10-53.10, 2021
2021
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