| Computational insights into mechanism of AIM4-mediated inhibition of aggregation of TDP-43 protein implicated in ALS and evidence for in vitro inhibition of liquid-liquid phase … A Girdhar, V Bharathi, VR Tiwari, S Abhishek, W Deeksha, US Mahawar, ... International journal of biological macromolecules 147, 117-130, 2020 | 28 | 2020 |
| Silver sulfadiazine loaded core-shell airbrushed nanofibers for burn wound healing application R Singh, P Roopmani, M Chauhan, SM Basu, W Deeksha, MD Kazem, ... International Journal of Pharmaceutics 613, 121358, 2022 | 16 | 2022 |
| Dynamic basis for auranofin drug recognition by thiol-reductases of human pathogens and intermediate coordinated adduct formation with catalytic cysteine residues S Abhishek, S Sivadas, M Satish, W Deeksha, E Rajakumara ACS omega 4 (5), 9593-9602, 2019 | 14 | 2019 |
| Structure-based redesigning of pentoxifylline analogs against selective phosphodiesterases to modulate sperm functional competence for assisted reproductive technologies M Satish, S Kumari, W Deeksha, S Abhishek, K Nitin, SK Adiga, P Hegde, ... Scientific Reports 11 (1), 12293, 2021 | 11 | 2021 |
| PAR recognition by PARP1 regulates DNA‐dependent activities and independently stimulates catalytic activity of PARP1 W Deeksha, S Abhishek, E Rajakumara The FEBS Journal 290 (21), 5098-5113, 2023 | 9 | 2023 |
| Mechanistic insights into recognition of symmetric methylated cytosines in CpG and non-CpG DNA by UHRF1 SRA S Abhishek, NK Nakarakanti, W Deeksha, E Rajakumara International Journal of Biological Macromolecules 170, 514-522, 2021 | 7 | 2021 |
| Mechanistic insights into allosteric regulation of methylated DNA and histone H3 recognition by SRA and SET domains of SUVH5 and the basis for di‐methylation of lysine residue S Abhishek, W Deeksha, E Rajakumara The FEBS Journal 290 (4), 1060-1077, 2023 | 4 | 2023 |
| Biochemical and dynamic basis for combinatorial recognition of H3R2K9me2 by dual domains of UHRF1 S Abhishek, MA Nivya, NK Nakarakanti, W Deeksha, S Khosla, ... Biochimie 149, 105-114, 2018 | 4 | 2018 |
| In vitro interaction of a C-terminal fragment of TDP-43 protein with human serum albumin modulates its aggregation S Nirwal, P Saravanan, A Bajpai, VD Meshram, G Raju, W Deeksha, ... The Journal of Physical Chemistry B 126 (45), 9137-9151, 2022 | 2 | 2022 |
| Allosteric crosstalk in modular proteins: Function fine-tuning and drug design S Abhishek, W Deeksha, KR Nethravathi, MD Davari, E Rajakumara Computational and Structural Biotechnology Journal, 2023 | 1 | 2023 |
| Regulation of PARP1 and its apoptotic variant activity by single‐stranded DNA W Deeksha, S Abhishek, J Giri, E Rajakumara The FEBS Journal 290 (18), 4533-4542, 2023 | 1 | 2023 |
| Helical and β-Turn Conformations in the Peptide Recognition Regions of the VIM1 PHD Finger Abrogate H3K4 Peptide Recognition S Abhishek, W Deeksha, E Rajakumara Biochemistry 60 (35), 2652-2662, 2021 | 1 | 2021 |
| Regulatory apoptotic fragment of PARP1 complements catalytic fragment for PAR and DNA-dependent activity but inhibits DNA-induced catalytic stimulation of PARP2 W Deeksha, E Rajakumara DNA repair 133, 103593, 2024 | | 2024 |
| In silico and in vitro studies suggest epigallocatechin gallate (EGCG), a polyphenol in green tea, can bind and modulate the aggregation and cytotoxicity of the full-length TDP … VD Meshram, R Balaji, P Saravanan, Y Subbamanda, W Deeksha, ... bioRxiv, 2023.12. 22.573011, 2023 | | 2023 |
| PAR recognition by multiple reader domains of PARP1 allosterically regulates the DNA-dependent activities and independently stimulates the catalytic activity of PARP1 W Deeksha, S Abhishek, E Rajakumara bioRxiv, 2021 | | 2021 |
| UHRF1-SRA recognizes symmetric non-CG methylated DNA through dual-flip out of 5-methyl cytosines NK Nakarakanti, S Abhishek, W Deeksha, E Rajakumara bioRxiv, 2019.12. 17.880419, 2019 | | 2019 |
Rajakumara Eerappa, PhDAssistant Professor, Biotechnology Department, Indian Institute of Technology-HyderabadVerified email at iith.ac.in
