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Ralph Scully
Ralph Scully
Professor of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School
Verified email at bidmc.harvard.edu
Title
Cited by
Cited by
Year
Association of BRCA1 with Rad51 in mitotic and meiotic cells
R Scully, J Chen, A Plug, Y Xiao, D Weaver, J Feunteun, T Ashley, ...
Cell 88 (2), 265-275, 1997
19011997
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
1701*2020
Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis
T Ikura, VV Ogryzko, M Grigoriev, R Groisman, J Wang, M Horikoshi, ...
Cell 102 (4), 463-473, 2000
12402000
Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage
R Scully, J Chen, RL Ochs, K Keegan, M Hoekstra, J Feunteun, ...
Cell 90 (3), 425-435, 1997
12231997
DNA double-strand break repair-pathway choice in somatic mammalian cells
R Scully, A Panday, R Elango, NA Willis
Nature reviews Molecular cell biology 20 (11), 698-714, 2019
11302019
SIRT1 redistribution on chromatin promotes genomic stability but alters gene expression during aging
P Oberdoerffer, S Michan, M McVay, R Mostoslavsky, J Vann, SK Park, ...
Cell 135 (5), 907-918, 2008
9642008
In search of the tumour-suppressor functions of BRCA1 and BRCA2
R Scully, DM Livingston
Nature 408 (6811), 429-432, 2000
8832000
Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells
J Chen, DP Silver, D Walpita, SB Cantor, AF Gazdar, G Tomlinson, ...
Molecular cell 2 (3), 317-328, 1998
8051998
Patterns of somatic structural variation in human cancer genomes
Y Li, ND Roberts, JA Wala, O Shapira, SE Schumacher, K Kumar, ...
Nature 578 (7793), 112-121, 2020
6962020
Functional interactions between BRCA1 and the checkpoint kinase ATR during genotoxic stress
RS Tibbetts, D Cortez, KM Brumbaugh, R Scully, D Livingston, SJ Elledge, ...
Genes & development 14 (23), 2989-3002, 2000
6962000
BRCA1 is a component of the RNA polymerase II holoenzyme
R Scully, SF Anderson, DM Chao, W Wei, L Ye, RA Young, DM Livingston, ...
Proceedings of the National Academy of Sciences 94 (11), 5605-5610, 1997
6781997
Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX
CH Bassing, KF Chua, JA Sekiguchi, H Suh, SR Whitlow, JC Fleming, ...
Proceedings of the National Academy of Sciences 99 (12), 8173-8178, 2002
6672002
The nuclear hormone receptor coactivator SRC-1 is a specific target of p300.
TP Yao, G Ku, N Zhou, R Scully, DM LIvINGSTON
Proceedings of the National Academy of Sciences 93 (20), 10626-10631, 1996
6251996
Mechanisms of double-strand break repair in somatic mammalian cells
AJ Hartlerode, R Scully
Biochemical Journal 423 (2), 157-168, 2009
5482009
Comprehensive analysis of chromothripsis in 2,658 human cancers using whole-genome sequencing
I Cortés-Ciriano, JJK Lee, R Xi, D Jain, YL Jung, L Yang, D Gordenin, ...
Nature genetics 52 (3), 331-341, 2020
5432020
Localization of human BRCA1 and its loss in high-grade, non-inherited breast carcinomas
CA Wilson, L Ramos, MR Villaseñor, KH Anders, MF Press, K Clarke, ...
Nature genetics 21 (2), 236-240, 1999
5191999
Analyses of non-coding somatic drivers in 2,658 cancer whole genomes
E Rheinbay, MM Nielsen, F Abascal, JA Wala, O Shapira, G Tiao, ...
Nature 578 (7793), 102-111, 2020
5032020
Combining a PI3K inhibitor with a PARP inhibitor provides an effective therapy for BRCA1-related breast cancer
A Juvekar, LN Burga, H Hu, EP Lunsford, YH Ibrahim, J Balmañà, ...
Cancer discovery 2 (11), 1048-1063, 2012
4562012
Genetic analysis of BRCA1 function in a defined tumor cell line
R Scully, S Ganesan, K Vlasakova, J Chen, M Socolovsky, DM Livingston
Molecular cell 4 (6), 1093-1099, 1999
4531999
Role of mammalian Mre11 in classical and alternative nonhomologous end joining
A Xie, A Kwok, R Scully
Nature structural & molecular biology 16 (8), 814-818, 2009
4182009
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