| Massively parallel de novo protein design for targeted therapeutics A Chevalier, DA Silva, GJ Rocklin, DR Hicks, R Vergara, P Murapa, ... Nature 550 (7674), 74-79, 2017 | 417 | 2017 |
| N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A G Yao, S Zhang, S Mahrhold, K Lam, D Stern, K Bagramyan, K Perry, ... Nature structural & molecular biology 23 (7), 656-662, 2016 | 114 | 2016 |
| Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B P Chen, L Tao, T Wang, J Zhang, A He, K Lam, Z Liu, X He, K Perry, ... Science 360 (6389), 664-669, 2018 | 113 | 2018 |
| Crystal structure of the SENP1 mutant C603S–SUMO complex reveals the hydrolytic mechanism of SUMO-specific protease Z Xu, SF Chau, KH Lam, HY Chan, TB Ng, SWN Au Biochemical Journal 398 (3), 345-352, 2006 | 71 | 2006 |
| Structure of the full-length Clostridium difficile toxin B P Chen, K Lam, Z Liu, FA Mindlin, B Chen, CB Gutierrez, L Huang, ... Nature structural & molecular biology 26 (8), 712-719, 2019 | 70 | 2019 |
| Diverse binding modes, same goal: The receptor recognition mechanism of botulinum neurotoxin KH Lam, G Yao, R Jin Progress in biophysics and molecular biology 117 (2-3), 225-231, 2015 | 47 | 2015 |
| Multiple conformations of the FliG C-terminal domain provide insight into flagellar motor switching KH Lam, WS Ip, YW Lam, SO Chan, TKW Ling, SWN Au Structure 20 (2), 315-325, 2012 | 46 | 2012 |
| Architecture of the botulinum neurotoxin complex: a molecular machine for protection and delivery KH Lam, R Jin Current opinion in structural biology 31, 89-95, 2015 | 44 | 2015 |
| Structural basis of FliG–FliM interaction in Helicobacter pylori KH Lam, WWL Lam, JYK Wong, LC Chan, M Kotaka, TKW Ling, DY Jin, ... Molecular microbiology 88 (4), 798-812, 2013 | 44 | 2013 |
| Crystal structure of the FliF-FliG complex from Helicobacter pylori yields insight into the assembly of the motor MS-C ring in the bacterial flagellum C Xue, KH Lam, H Zhang, K Sun, SH Lee, X Chen, SWN Au Journal of biological chemistry, 2017 | 36 | 2017 |
| SUMO proteases: redox regulation and biological consequences Z Xu, HY Chan, WL Lam, KH Lam, LSM Lam, TB Ng, SWN Au Antioxidants & Redox Signaling 11 (6), 1453-1484, 2009 | 36 | 2009 |
| Structural basis of the pH-dependent assembly of a botulinum neurotoxin complex T Matsui, S Gu, K Lam, LG Carter, A Rummel, II Mathews, R Jin Journal of molecular biology 426 (22), 3773-3782, 2014 | 35 | 2014 |
| A viral-fusion-peptide-like molecular switch drives membrane insertion of botulinum neurotoxin A1 K Lam, Z Guo, N Krez, T Matsui, K Perry, J Weisemann, A Rummel, ... Nature communications 9 (1), 5367, 2018 | 34 | 2018 |
| Structural insights into rational design of single-domain antibody-based antitoxins against botulinum neurotoxins K Lam, JM Tremblay, E Vazquez-Cintron, K Perry, C Ondeck, RP Webb, ... Cell reports 30 (8), 2526-2539. e6, 2020 | 29 | 2020 |
| Crystal structure of the receptor-binding domain of botulinum neurotoxin type HA, also known as type FA or H G Yao, K Lam, K Perry, J Weisemann, A Rummel, R Jin Toxins 9 (3), 93, 2017 | 29 | 2017 |
| Crystal Structure of Activated CheY1 from Helicobacter pylori KH Lam, TKW Ling, SWN Au Journal of bacteriology 192 (9), 2324-2334, 2010 | 29 | 2010 |
| Botulinum neurotoxin A complex recognizes host carbohydrates through its hemagglutinin component G Yao, K Lee, S Gu, KH Lam, R Jin Toxins 6 (2), 624-635, 2014 | 25 | 2014 |
| High-resolution crystal structure of HA33 of botulinum neurotoxin type B progenitor toxin complex K Lee, KH Lam, AM Kruel, K Perry, A Rummel, R Jin Biochemical and biophysical research communications 446 (2), 568-573, 2014 | 22 | 2014 |
| The hypothetical protein P47 of Clostridium botulinum E1 strain Beluga has a structural topology similar to bactericidal/permeability-increasing protein K Lam, R Qi, S Liu, A Kroh, G Yao, K Perry, A Rummel, R Jin Toxicon 147, 19-26, 2018 | 19 | 2018 |
| A camelid single-domain antibody neutralizes botulinum neurotoxin A by blocking host receptor binding G Yao, K Lam, J Weisemann, L Peng, N Krez, K Perry, CB Shoemaker, ... Scientific reports 7 (1), 7438, 2017 | 19 | 2017 |
