| Bisubstrate inhibitors of protein kinases: from principle to practical applications D Lavogina, E Enkvist, A Uri ChemMedChem: Chemistry Enabling Drug Discovery 5 (1), 23-34, 2010 | 132 | 2010 |
| Conjugation of adenosine and hexa-(D-arginine) leads to a nanomolar bisubstrate-analog inhibitor of basophilic protein kinases E Enkvist, D Lavogina, G Raidaru, A Vaasa, I Viil, M Lust, K Viht, A Uri Journal of medicinal chemistry 49 (24), 7150-7159, 2006 | 81 | 2006 |
| High-affinity bisubstrate probe for fluorescence anisotropy binding/displacement assays with protein kinases PKA and ROCK A Vaasa, I Viil, E Enkvist, K Viht, G Raidaru, D Lavogina, A Uri Analytical biochemistry 385 (1), 85-93, 2009 | 77 | 2009 |
| Phosphorylation of Notch1 by Pim kinases promotes oncogenic signaling in breast and prostate cancer cells NM Santio, SKJ Landor, L Vahtera, J Ylä-Pelto, E Paloniemi, SY Imanishi, ... Oncotarget 7 (28), 43220, 2016 | 66 | 2016 |
| Protein-induced long lifetime luminescence of nonmetal probes E Enkvist, A Vaasa, M Kasari, M Kriisa, T Ivan, K Ligi, G Raidaru, A Uri ACS chemical biology 6 (10), 1052-1062, 2011 | 54 | 2011 |
| Structural analysis of ARC-type inhibitor (ARC-1034) binding to protein kinase A catalytic subunit and rational design of bisubstrate analogue inhibitors of basophilic protein … D Lavogina, M Lust, I Viil, N Konig, G Raidaru, J Rogozina, E Enkvist, ... Journal of medicinal chemistry 52 (2), 308-321, 2009 | 54 | 2009 |
| Adenosine-5′-carboxylic acid peptidyl derivatives as inhibitors of protein kinases M Loog, A Uri, G Raidaru, J Järv, P Ek Bioorganic & medicinal chemistry letters 9 (10), 1447-1452, 1999 | 51 | 1999 |
| Surface-plasmon-resonance-based biosensor with immobilized bisubstrate analog inhibitor for the determination of affinities of ATP-and protein-competitive ligands of cAMP … K Viht, S Schweinsberg, M Lust, A Vaasa, G Raidaru, D Lavogina, A Uri, ... Analytical biochemistry 362 (2), 268-277, 2007 | 49 | 2007 |
| Novel galanin receptor ligands M Pooga, A Jureus, K Rezaei, H Hasanvan, K SAAR, K Kask, P Kjellen, ... The Journal of peptide research 51 (1), 65-74, 1998 | 46 | 1998 |
| A subnanomolar fluorescent probe for protein kinase CK2 interaction studies E Enkvist, K Viht, N Bischoff, J Vahter, S Saaver, G Raidaru, OG Issinger, ... Organic & biomolecular chemistry 10 (43), 8645-8653, 2012 | 44 | 2012 |
| 2-Alkylthio-substituted platelet P2Y12 receptor antagonists reveal pharmacological identity between the rat brain Gi-linked ADP receptors and P2Y12 KS Vasiljev, A Uri, JT Laitinen Neuropharmacology 45 (1), 145-154, 2003 | 44 | 2003 |
| Diversity of bisubstrate binding modes of adenosine analogue–oligoarginine conjugates in protein kinase A and implications for protein substrate interactions A Pflug, J Rogozina, D Lavogina, E Enkvist, A Uri, RA Engh, ... Journal of molecular biology 403 (1), 66-77, 2010 | 43 | 2010 |
| [35S]GTPγS autoradiography reveals a wide distribution of Gi/o‐linked ADP receptors in the nervous system: close similarities with the platelet P2YADP receptor JT Laitinen, A Uri, G Raidaru, R Miettinen Journal of neurochemistry 77 (2), 505-518, 2001 | 40 | 2001 |
| Small-molecule FRET probes for protein kinase activity monitoring in living cells A Vaasa, M Lust, A Terrin, A Uri, M Zaccolo Biochemical and biophysical research communications 397 (4), 750-755, 2010 | 37 | 2010 |
| Fluorometric TLC assay for evaluation of protein kinase inhibitors K Viht, A Vaasa, G Raidaru, E Enkvist, A Uri Analytical biochemistry 340 (1), 165-170, 2005 | 34 | 2005 |
| Time-gated luminescence assay using nonmetal probes for determination of protein kinase activity-based disease markers M Kasari, P Padrik, A Vaasa, K Saar, K Leppik, J Soplepmann, A Uri Analytical biochemistry 422 (2), 79-88, 2012 | 32 | 2012 |
| Acetoxymethyl Ester of Tetrabromobenzimidazole–Peptoid Conjugate for Inhibition of Protein Kinase CK2 in Living Cells K Viht, S Saaver, J Vahter, E Enkvist, D Lavogina, H Sinijärv, G Raidaru, ... Bioconjugate chemistry 26 (12), 2324-2335, 2015 | 29 | 2015 |
| Time-gated luminescence microscopy with responsive nonmetal probes for mapping activity of protein kinases in living cells A Vaasa, K Ligi, S Mohandessi, E Enkvist, A Uri, LW Miller Chemical communications 48 (68), 8595-8597, 2012 | 27 | 2012 |
| Benzoselenadiazole-based responsive long-lifetime photoluminescent probes for protein kinases R Ekambaram, E Enkvist, G babu Manoharan, M Ugandi, M Kasari, K Viht, ... Chemical communications 50 (31), 4096-4098, 2014 | 25 | 2014 |
| Bisubstrate fluorescent probes and biosensors in binding assays for HTS of protein kinase inhibitors A Uri, M Lust, A Vaasa, D Lavogina, K Viht, E Enkvist Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1804 (3), 541-546, 2010 | 25 | 2010 |
