| In vivo demonstration that α-synuclein oligomers are toxic B Winner, R Jappelli, SK Maji, PA Desplats, L Boyer, S Aigner, C Hetzer, ... Proceedings of the National Academy of Sciences 108 (10), 4194-4199, 2011 | 1666 | 2011 |
| A Designed Inhibitor of p53 Aggregation Rescues p53 Tumor Suppression in Ovarian Carcinomas A Soragni, DM Janzen, LM Johnson, AG Lindgren, ATQ Nguyen, ... Cancer cell 29 (1), 90-103, 2016 | 332 | 2016 |
| Mechanism of membrane interaction and disruption by α-synuclein NP Reynolds*, A Soragni*, M Rabe, D Verdes, E Liverani, S Handschin, ... Journal of the American Chemical Society 133 (48), 19366-19375, 2011 | 239 | 2011 |
| Organoids Z Zhao, X Chen, AM Dowbaj, A Sljukic, K Bratlie, L Lin, ELS Fong, ... Nature Reviews Methods Primers 2 (1), 94, 2022 | 216 | 2022 |
| A simple high-throughput approach identifies actionable drug sensitivities in patient-derived tumor organoids N Phan, JJ Hong, B Tofig, M Mapua, D Elashoff, NA Moatamed, J Huang, ... Communications biology 2 (1), 1-11, 2019 | 207 | 2019 |
| The amyloid–Congo red interface at atomic resolution AK Schütz, A Soragni, S Hornemann, A Aguzzi, M Ernst, A Böckmann, ... Angewandte Chemie-International Edition 50 (26), 5956, 2011 | 161 | 2011 |
| Toxicity of Eosinophil MBP Is Repressed by Intracellular Crystallization and Promoted by Extracellular Aggregation A Soragni, S Yousefi, C Stoeckle, AB Soriaga, MR Sawaya, E Kozlowski, ... Molecular cell 57 (6), 1011-1021, 2015 | 114 | 2015 |
| In vitro analysis of protein-operator interactions of the NikR and fur metal-responsive regulators of coregulated genes in Helicobacter pylori I Delany, R Ieva, A Soragni, M Hilleringmann, R Rappuoli, V Scarlato Journal of bacteriology 187 (22), 7703-7715, 2005 | 112 | 2005 |
| Structural Characterization of Binding of Cu (II) to Tau Protein A Soragni, B Zambelli, MD Mukrasch, J Biernat, S Jeganathan, ... Biochemistry 47 (41), 10841-10851, 2008 | 111 | 2008 |
| Solution structure of selenoprotein W and NMR analysis of its interaction with 14-3-3 proteins FL Aachmann, DE Fomenko, A Soragni, VN Gladyshev, A Dikiy Journal of Biological Chemistry 282 (51), 37036-37044, 2007 | 103 | 2007 |
| The mechanism of prion inhibition by HET-S J Greenwald, C Buhtz, C Ritter, W Kwiatkowski, S Choe, ML Maddelein, ... Molecular cell 38 (6), 889-899, 2010 | 99 | 2010 |
| Superresolution imaging of amyloid fibrils with binding-activated probes J Ries, V Udayar, A Soragni, S Hornemann, KPR Nilsson, R Riek, C Hock, ... ACS chemical neuroscience 4 (7), 1057-1061, 2013 | 94 | 2013 |
| On-Surface Aggregation of α-Synuclein at Nanomolar Concentrations Results in Two Distinct Growth Mechanisms M Rabe, A Soragni, NP Reynolds, D Verdes, E Liverani, R Riek, S Seeger ACS chemical neuroscience 4 (3), 408-417, 2013 | 70 | 2013 |
| Infectious and Noninfectious Amyloids of the HET‐s (218–289) Prion Have Different NMR Spectra C Wasmer, A Soragni, R Sabaté, A Lange, R Riek, BH Meier Angewandte Chemie International Edition 47 (31), 5839-5841, 2008 | 60 | 2008 |
| Structural similarity between the prion domain of HET-s and a homologue can explain amyloid cross-seeding in spite of limited sequence identity C Wasmer, A Zimmer, R Sabaté, A Soragni, SJ Saupe, C Ritter, BH Meier Journal of molecular biology 402 (2), 311-325, 2010 | 59 | 2010 |
| A Combined Solid‐State NMR and MD Characterization of the Stability and Dynamics of the HET‐s (218‐289) Prion in its Amyloid Conformation A Lange, Z Gattin, H Van Melckebeke, C Wasmer, A Soragni, ... ChemBioChem 10 (10), 1657-1665, 2009 | 49 | 2009 |
| Personalized chordoma organoids for drug discovery studies A Al Shihabi, A Davarifar, HTL Nguyen, N Tavanaie, SD Nelson, ... Science advances 8 (7), eabl3674, 2022 | 37 | 2022 |
| Of scientists and tweets A Soragni, A Maitra Nature Reviews Cancer 19 (9), 479-480, 2019 | 20 | 2019 |
| Patient-Derived Tumor Organoid Rings for Histologic Characterization and High-Throughput Screening HTL Nguyen, A Soragni STAR Protocols 1 (2), 100056, 2020 | 18 | 2020 |
| Drug screening at single-organoid resolution via bioprinting and interferometry PJ Tebon, B Wang, AL Markowitz, A Davarifar, BL Tsai, P Krawczuk, ... Nature Communications 14 (1), 3168, 2023 | 17 | 2023 |
