| Guidelines for the use and interpretation of assays for monitoring autophagy DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ... Autophagy 12 (1), 1-222, 2016 | 2793 | 2016 |
| TRPV3 is a calcium-permeable temperature-sensitive cation channel H Xu, IS Ramsey, SA Kotecha, MM Moran, JA Chong, D Lawson, P Ge, ... Nature 418 (6894), 181, 2002 | 782 | 2002 |
| Oregano, thyme and clove-derived flavors and skin sensitizers activate specific TRP channels H Xu, M Delling, JC Jun, DE Clapham Nature neuroscience 9 (5), 628, 2006 | 525 | 2006 |
| Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB DL Medina, S Di Paola, I Peluso, A Armani, D De Stefani, R Venditti, ... Nature cell biology 17 (3), 288, 2015 | 443 | 2015 |
| A prokaryotic voltage-gated sodium channel D Ren, B Navarro, H Xu, L Yue, Q Shi, DE Clapham Science 294 (5550), 2372-2375, 2001 | 435 | 2001 |
| Phosphatidylinositol 3-kinase activates ERK in primary sensory neurons and mediates inflammatory heat hyperalgesia through TRPV1 sensitization ZY Zhuang, H Xu, DE Clapham, RR Ji Journal of Neuroscience 24 (38), 8300-8309, 2004 | 405 | 2004 |
| PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosome X Dong, D Shen, X Wang, T Dawson, X Li, Q Zhang, X Cheng, Y Zhang, ... Nature communications 1, 38, 2010 | 376 | 2010 |
| Camphor activates and strongly desensitizes the transient receptor potential vanilloid subtype 1 channel in a vanilloid-independent mechanism H Xu, NT Blair, DE Clapham Journal of Neuroscience 25 (39), 8924-8937, 2005 | 376 | 2005 |
| The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel XP Dong, X Cheng, E Mills, M Delling, F Wang, T Kurz, H Xu Nature 455 (7215), 992, 2008 | 353 | 2008 |
| TRP ion channels in the nervous system MM Moran, H Xu, DE Clapham Current opinion in neurobiology 14 (3), 362-369, 2004 | 329 | 2004 |
| TPC proteins are phosphoinositide-activated sodium-selective ion channels in endosomes and lysosomes X Wang, X Zhang, X Dong, M Samie, X Li, X Cheng, A Goschka, D Shen, ... Cell 151 (2), 372-383, 2012 | 318 | 2012 |
| Lysosomal physiology H Xu, D Ren Annual review of physiology 77, 57-80, 2015 | 292 | 2015 |
| Lipid storage disorders block lysosomal trafficking by inhibiting a TRP channel and lysosomal calcium release D Shen, X Wang, X Li, X Zhang, Z Yao, S Dibble, X Dong, T Yu, ... Nature communications 3, 731, 2012 | 240 | 2012 |
| TRP channel regulates EGFR signaling in hair morphogenesis and skin barrier formation X Cheng, J Jin, L Hu, D Shen, X Dong, MA Samie, J Knoff, B Eisinger, ... Cell 141 (2), 331-343, 2010 | 185 | 2010 |
| Mechanisms of brain iron transport: insight into neurodegeneration and CNS disorders E Mills, X Dong, F Wang, H Xu Future medicinal chemistry 2 (1), 51-64, 2010 | 181 | 2010 |
| Hippo/YAP-mediated rigidity-dependent motor neuron differentiation of human pluripotent stem cells Y Sun, KMA Yong, LG Villa-Diaz, X Zhang, W Chen, R Philson, S Weng, ... Nature materials 13 (6), 599, 2014 | 176 | 2014 |
| Mucolipins: intracellular TRPML1‐3 channels X Cheng, D Shen, M Samie, H Xu FEBS letters 584 (10), 2013-2021, 2010 | 160 | 2010 |
| A superfamily of voltage-gated sodium channels in bacteria R Koishi, H Xu, D Ren, B Navarro, BW Spiller, Q Shi, DE Clapham Journal of Biological Chemistry 279 (10), 9532-9538, 2004 | 158 | 2004 |
| Activating mutation in a mucolipin transient receptor potential channel leads to melanocyte loss in varitint–waddler mice H Xu, M Delling, L Li, X Dong, DE Clapham Proceedings of the National Academy of Sciences 104 (46), 18321-18326, 2007 | 148 | 2007 |
| A molecular mechanism to regulate lysosome motility for lysosome positioning and tubulation X Li, N Rydzewski, A Hider, X Zhang, J Yang, W Wang, Q Gao, X Cheng, ... Nature cell biology 18 (4), 404, 2016 | 145 | 2016 |
David ClaphamHHMI, Janelia Research Campus, Ashburn, Virginia, USAVerified email at janelia.hhmi.org
