| A fundamental study of the PCR amplification of GC-rich DNA templates TG Mamedov, E Pienaar, SE Whitney, JR TerMaat, G Carvill, R Goliath, ... Computational biology and chemistry 32 (6), 452-457, 2008 | 184 | 2008 |
| Ribosome kinetics and aa-tRNA competition determine rate and fidelity of peptide synthesis A Fluitt, E Pienaar, H Viljoen Computational biology and chemistry 31 (5-6), 335-346, 2007 | 165 | 2007 |
| A review of computational and mathematical modeling contributions to our understanding of Mycobacterium tuberculosis within-host infection and treatment D Kirschner, E Pienaar, S Marino, JJ Linderman Current Opinion in Systems Biology 3, 170-185, 2017 | 71 | 2017 |
| A computational tool integrating host immunity with antibiotic dynamics to study tuberculosis treatment E Pienaar, NA Cilfone, PL Lin, V Dartois, JT Mattila, JR Butler, JAL Flynn, ... Journal of theoretical biology 367, 166-179, 2015 | 70 | 2015 |
| A quantitative model of error accumulation during PCR amplification E Pienaar, M Theron, M Nelson, HJ Viljoen Computational biology and chemistry 30 (2), 102-111, 2006 | 66 | 2006 |
| In vitro granuloma models of tuberculosis: potential and challenges P Elkington, M Lerm, N Kapoor, R Mahon, E Pienaar, D Huh, D Kaushal, ... The Journal of Infectious Diseases 219 (12), 1858-1866, 2019 | 65 | 2019 |
| Comparing efficacies of moxifloxacin, levofloxacin and gatifloxacin in tuberculosis granulomas using a multi-scale systems pharmacology approach E Pienaar, J Sarathy, B Prideaux, J Dietzold, V Dartois, DE Kirschner, ... PLoS computational biology 13 (8), e1005650, 2017 | 65 | 2017 |
| Efficiency of the polymerase chain reaction CS Booth, E Pienaar, JR Termaat, SE Whitney, TM Louw, HJ Viljoen Chemical engineering science 65 (17), 4996-5006, 2010 | 61 | 2010 |
| Replication rates of Mycobacterium tuberculosis in human macrophages do not correlate with mycobacterial antibiotic susceptibility J Raffetseder, E Pienaar, R Blomgran, D Eklund, VP Brodin, H Andersson, ... PLoS One 9 (11), e112426, 2014 | 57 | 2014 |
| Replication rates of Mycobacterium tuberculosis in human macrophages do not correlate with mycobacterial antibiotic susceptibility J Raffetseder, E Pienaar, R Blomgran, D Eklund, VP Brodin, H Andersson, ... PloS one 9 (11), e112426, 2014 | 57 | 2014 |
| Fluoroquinolone efficacy against tuberculosis is driven by penetration into lesions and activity against resident bacterial populations J Sarathy, L Blanc, N Alvarez-Cabrera, P O'Brien, I Dias-Freedman, ... Antimicrobial Agents and Chemotherapy, AAC. 02516-18, 2019 | 53 | 2019 |
| Rapid community-driven development of a SARS-CoV-2 tissue simulator M Getz, Y Wang, G An, A Becker, C Cockrell, N Collier, M Craig, CL Davis, ... bioRxiv, 2020 | 52 | 2020 |
| Multiscale model of Mycobacterium tuberculosis infection maps metabolite and gene perturbations to granuloma sterilization predictions E Pienaar, WM Matern, JJ Linderman, JS Bader, DE Kirschner Infection and immunity 84 (5), 1650-1669, 2016 | 52 | 2016 |
| In silico evaluation and exploration of antibiotic tuberculosis treatment regimens E Pienaar, V Dartois, JJ Linderman, DE Kirschner BMC systems biology 9 (1), 79, 2015 | 50 | 2015 |
| Deletion of TGF-β1 Increases Bacterial Clearance by Cytotoxic T Cells in a Tuberculosis Granuloma Model HC Warsinske, E Pienaar, J Linderman, M Joshua, D Kirschner Frontiers in Immunology 8, 1843, 2017 | 47 | 2017 |
| Antimycobacterial activity of selected medicinal plants traditionally used in Sudan to treat infectious diseases N Abuzeid, S Kalsum, RJ Koshy, M Larsson, M Glader, H Andersson, ... Journal of ethnopharmacology 157, 134-139, 2014 | 36 | 2014 |
| A multi-scale approach to designing therapeutics for tuberculosis JJ Linderman, NA Cilfone, E Pienaar, C Gong, DE Kirschner Integrative Biology 7 (5), 591-609, 2015 | 35 | 2015 |
| A model of tuberculosis transmission and intervention strategies in an urban residential area E Pienaar, AM Fluitt, SE Whitney, AG Freifeld, HJ Viljoen Computational biology and chemistry 34 (2), 86-96, 2010 | 35 | 2010 |
| Systems pharmacology approach toward the design of inhaled formulations of rifampicin and isoniazid for treatment of tuberculosis NA Cilfone, E Pienaar, GM Thurber, DE Kirschner, JJ Linderman CPT: pharmacometrics & systems pharmacology 4 (3), 193-203, 2015 | 30 | 2015 |
| Emergence and selection of isoniazid and rifampin resistance in tuberculosis granulomas E Pienaar, JJ Linderman, DE Kirschner PloS one 13 (5), e0196322, 2018 | 29 | 2018 |
