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Christian Beusch
Christian Beusch
Institutionen för medicinsk biokemi och biofysik, Karolinska Institutet
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Titel
Zitiert von
Zitiert von
Jahr
Proteome Integral Solubility Alteration: A High-Throughput Proteomics Assay for Target Deconvolution
M Gaetani, P Sabatier, AA Saei, CM Beusch, Z Yang, SL Lundström, ...
Journal of proteome research 18 (11), 4027-4037, 2019
1692019
Comprehensive chemical proteomics for target deconvolution of the redox active drug auranofin
AA Saei, H Gullberg, P Sabatier, CM Beusch, K Johansson, B Lundgren, ...
Redox biology 32, 101491, 2020
672020
ProTargetMiner as a proteome signature library of anticancer molecules for functional discovery
AA Saei, CM Beusch, A Chernobrovkin, P Sabatier, B Zhang, ÜG Tokat, ...
Nature communications 10 (1), 5715, 2019
612019
System-wide identification and prioritization of enzyme substrates by thermal analysis
AA Saei, CM Beusch, P Sabatier, JA Wells, H Gharibi, Z Meng, ...
Nature communications 12 (1), 1296, 2021
54*2021
Quantitative selection analysis of bacteriophage φCbK susceptibility in Caulobacter crescentus
M Christen, C Beusch, Y Bösch, D Cerletti, CE Flores-Tinoco, ...
Journal of molecular biology 428 (2), 419-430, 2016
462016
A subset of antibodies targeting citrullinated proteins confers protection from rheumatoid arthritis
Y He, C Ge, À Moreno-Giró, B Xu, CM Beusch, K Sandor, J Su, L Cheng, ...
Nature communications 14 (1), 691, 2023
262023
Comprehensive chemical proteomics analyses reveal that the new TRi-1 and TRi-2 compounds are more specific thioredoxin reductase 1 inhibitors than auranofin
P Sabatier, CM Beusch, R Gencheva, Q Cheng, R Zubarev, ESJ Arnér
Redox Biology 48, 102184, 2021
242021
An integrative proteomics method identifies a regulator of translation during stem cell maintenance and differentiation
P Sabatier, CM Beusch, AA Saei, M Aoun, N Moruzzi, A Coelho, N Leijten, ...
Nature communications 12 (1), 6558, 2021
192021
Ion-based proteome-integrated solubility alteration assays for systemwide profiling of protein–molecule interactions
CM Beusch, P Sabatier, RA Zubarev
Analytical Chemistry 94 (19), 7066-7074, 2022
172022
GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics
SC Wright, A Motso, S Koutsilieri, CM Beusch, P Sabatier, A Berghella, ...
Nature communications 14 (1), 6243, 2023
102023
System-wide profiling by proteome integral solubility alteration assay of drug residence times for target characterization
P Sabatier, CM Beusch, Z Meng, RA Zubarev
Analytical Chemistry 94 (45), 15772-15780, 2022
62022
Antigen-presenting autoreactive B cells activate regulatory T cells and suppress autoimmune arthritis in mice
M Aoun, A Coelho, A Krämer, A Saxena, P Sabatier, CM Beusch, ...
Journal of Experimental Medicine 220 (11), e20230101, 2023
52023
Ultralight ultrafast enzymes
X Zhang, Z Meng, C Beusch, H Gharibi, Q Cheng, L Stefano, J Wang, ...
42021
Wnt/β-catenin and NFκB signaling synergize to trigger growth-factor-free regeneration of adult primary human hepatocytes
N Oliva-Vilarnau, CM Beusch, P Sabatier, E Sakaraki, A Tjaden, L Graetz, ...
Hepatology, 10.1097, 2023
32023
SIESTA as a universal unbiased proteomics approach for identification and prioritization of enzyme substrates
AA Saei, CM Beusch, P Sabatier, JA Wells, H Gharibi, Z Meng, ...
32021
Therapy targeting antigen-specific T cells by a peptide-based tolerizing vaccine against autoimmune arthritis
V Urbonaviciute, L Romero-Castillo, B Xu, H Luo, N Schneider, S Weisse, ...
Proceedings of the National Academy of Sciences 120 (25), e2218668120, 2023
22023
Ultralight Ultrafast Enzymes
X Zhang, Z Meng, CM Beusch, H Gharibi, Q Cheng, H Lyu, L Di Stefano, ...
Angewandte Chemie 136 (3), e202316488, 2024
12024
Analysis of local extracellular matrix identifies different aetiologies behind bicuspid and tricuspid aortic valve degeneration and suggests therapies
CM Beusch, OE Simonson, JO Wedin, P Sabatier, U Felldin, S Kadekar, ...
Cellular and Molecular Life Sciences 80 (9), 268, 2023
12023
Do light eaters live shorter lives? The case of ultralight Caenorhabditis elegans
X Zhang, H Gharibi, CM Beusch, Z Meng, A Saei Dibavar, M Gaetani, ...
bioRxiv, 2024.02. 13.580069, 2024
2024
Method and Apparatus for Analysing Samples of Biomolecules Using Mass Spectrometry with Data-Independent Acquisition
R Zubarev, C Beusch
US Patent App. 17/673,409, 2022
2022
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