| TGF-β targets the hippo pathway scaffold RASSF1A to facilitate YAP/SMAD2 nuclear translocation DE Pefani, D Pankova, AG Abraham, AM Grawenda, N Vlahov, S Scrace, ... Molecular cell 63 (1), 156-166, 2016 | 147 | 2016 |
| Mcidas and GemC1 are key regulators for the generation of multiciliated ependymal cells in the adult neurogenic niche C Kyrousi, M Arbi, GA Pilz, DE Pefani, ME Lalioti, J Ninkovic, M Götz, ... Development 142 (21), 3661-3674, 2015 | 101 | 2015 |
| RASSF1A–LATS1 signalling stabilizes replication forks by restricting CDK2-mediated phosphorylation of BRCA2 DE Pefani, R Latusek, I Pires, AM Grawenda, KS Yee, G Hamilton, ... Nature Cell Biology 16 (10), 962-971, 2014 | 97 | 2014 |
| Integrating the DNA damage and protein stress responses during cancer development and treatment VG Gorgoulis, DE Pefani, IS Pateras, IP Trougakos The Journal of pathology 246 (1), 12-40, 2018 | 90 | 2018 |
| GemC1 controls multiciliogenesis in the airway epithelium M Arbi, DE Pefani, C Kyrousi, ME Lalioti, A Kalogeropoulou, ... EMBO reports 17 (3), 400-413, 2016 | 84 | 2016 |
| RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73 A Papaspyropoulos, L Bradley, A Thapa, CY Leung, K Toskas, D Koennig, ... Nature communications 9 (1), 424, 2018 | 81 | 2018 |
| Idas, a novel phylogenetically conserved geminin-related protein, binds to geminin and is required for cell cycle progression DE Pefani, M Dimaki, M Spella, N Karantzelis, E Mitsiki, C Kyrousi, ... Journal of Biological Chemistry 286 (26), 23234-23246, 2011 | 52 | 2011 |
| A prototypical non-malignant epithelial model to study genome dynamics and concurrently monitor micro-RNAs and proteins in situ during oncogene-induced … ES Komseli, IS Pateras, T Krejsgaard, K Stawiski, SV Rizou, A Polyzos, ... BMC genomics 19, 1-22, 2018 | 50 | 2018 |
| Hippo pathway and protection of genome stability in response to DNA damage DE Pefani, E O'Neill The FEBS journal 283 (8), 1392-1403, 2016 | 47 | 2016 |
| RASSF 1A is required for the maintenance of nuclear actin levels M Chatzifrangkeskou, DE Pefani, M Eyres, I Vendrell, R Fischer, ... The EMBO journal 38 (16), e101168, 2019 | 40 | 2019 |
| MST2 kinase suppresses rDNA transcription in response to DNA damage by phosphorylating nucleolar histone H2B DE Pefani, ML Tognoli, D Pirincci Ercan, V Gorgoulis, E O'Neill The EMBO journal 37 (15), e98760, 2018 | 39 | 2018 |
| AKT regulates NPM dependent ARF localization and p53mut stability in tumors G Hamilton, AG Abraham, J Morton, O Sampson, DE Pefani, ... Oncotarget 5 (15), 6142, 2014 | 36 | 2014 |
| A recurrent chromosomal inversion suffices for driving escape from oncogene-induced senescence via subTAD reorganization CP Zampetidis, P Galanos, A Angelopoulou, Y Zhu, A Polyzou, ... Molecular Cell 81 (23), 4907-4923. e8, 2021 | 34 | 2021 |
| Controlling centriole numbers: Geminin family members as master regulators of centriole amplification and multiciliogenesis M Arbi, DE Pefani, S Taraviras, Z Lygerou Chromosoma 127, 151-174, 2018 | 26 | 2018 |
| Ribosomal DNA and the nucleolus at the heart of aging E Kasselimi, DE Pefani, S Taraviras, Z Lygerou Trends in Biochemical Sciences 47 (4), 328-341, 2022 | 25 | 2022 |
| The structure of the GemC1 coiled coil and its interaction with the Geminin family of coiled-coil proteins C Caillat, A Fish, DE Pefani, S Taraviras, Z Lygerou, A Perrakis Acta Crystallographica Section D: Biological Crystallography 71 (11), 2278-2286, 2015 | 23 | 2015 |
| The Geminin and Idas coiled coils preferentially form a heterodimer that inhibits Geminin function in DNA replication licensing C Caillat, DE Pefani, PJ Gillespie, S Taraviras, JJ Blow, Z Lygerou, ... Journal of Biological Chemistry 288 (44), 31624-31634, 2013 | 23 | 2013 |
| Safeguarding genome stability: RASSF1A tumor suppressor regulates BRCA2 at stalled forks DE Pefani, E O'Neill Cell Cycle 14 (11), 1624-1630, 2015 | 12 | 2015 |
| 53BP1‐mediated recruitment of RASSF1A to ribosomal DNA breaks promotes local ATM signaling S Tsaridou, G Velimezi, F Willenbrock, M Chatzifrangkeskou, W Elsayed, ... EMBO reports 23 (8), e54483, 2022 | 5 | 2022 |
| Genomic instability is an early event driving chromatin reorganization and escape from oncogene-induced senescence C Zampetidis, P Galanos, A Angelopoulou, Y Zhu, T Karamitros, ... bioRxiv, 2020.12. 20.423639, 2020 | 1 | 2020 |
