The activities and function of molecular chaperones in the endoplasmic reticulum TM Buck, CM Wright, JL Brodsky Seminars in cell & developmental biology 18 (6), 751-761, 2007 | 128 | 2007 |
The endoplasmic reticulum–associated degradation of the epithelial sodium channel requires a unique complement of molecular chaperones TM Buck, AR Kolb, CR Boyd, TR Kleyman, JL Brodsky Molecular biology of the cell 21 (6), 1047-1058, 2010 | 114 | 2010 |
A novel tripartite motif involved in aquaporin topogenesis, monomer folding and tetramerization TM Buck, J Wagner, S Grund, WR Skach Nature structural & molecular biology 14 (8), 762-769, 2007 | 83 | 2007 |
The Lhs1/GRP170 chaperones facilitate the endoplasmic reticulum-associated degradation of the epithelial sodium channel TM Buck, L Plavchak, A Roy, BF Donnelly, OB Kashlan, TR Kleyman, ... Journal of Biological Chemistry 288 (25), 18366-18380, 2013 | 60 | 2013 |
Evidence for stabilization of aquaporin-2 folding mutants by N-linked glycosylation in endoplasmic reticulum TM Buck, J Eledge, WR Skach American Journal of Physiology-Cell Physiology 287 (5), C1292-C1299, 2004 | 55 | 2004 |
Cooperativity and flexibility of cystic fibrosis transmembrane conductance regulator transmembrane segments participate in membrane localization of a charged residue K Carveth, T Buck, V Anthony, WR Skach Journal of Biological Chemistry 277 (42), 39507-39514, 2002 | 44 | 2002 |
Aberrant folding of a mutant Stat5b causes growth hormone insensitivity and proteasomal dysfunction DJ Chia, E Subbian, TM Buck, V Hwa, RG Rosenfeld, WR Skach, ... Journal of Biological Chemistry 281 (10), 6552-6558, 2006 | 39 | 2006 |
Differential stability of biogenesis intermediates reveals a common pathway for aquaporin-1 topological maturation TM Buck, WR Skach Journal of Biological Chemistry 280 (1), 261-269, 2005 | 37 | 2005 |
Interactions between intersubunit transmembrane domains regulate the chaperone-dependent degradation of an oligomeric membrane protein TM Buck, AS Jordahl, ME Yates, GM Preston, E Cook, TR Kleyman, ... Biochemical Journal 474 (3), 357-376, 2017 | 31 | 2017 |
N-linked glycans are required on epithelial Na+ channel subunits for maturation and surface expression OB Kashlan, CL Kinlough, MM Myerburg, S Shi, J Chen, BM Blobner, ... American Journal of Physiology-Renal Physiology 314 (3), F483-F492, 2018 | 29 | 2018 |
Saccharomyces cerivisiae as a model system for kidney disease: what can yeast tell us about renal function? AR Kolb, TM Buck, JL Brodsky American Journal of Physiology-Renal Physiology 301 (1), F1-F11, 2011 | 23 | 2011 |
Hsp104 facilitates the endoplasmic‐reticulum–associated degradation of disease‐associated and aggregation‐prone substrates LM Doonan, CJ Guerriero, GM Preston, TM Buck, N Khazanov, EA Fisher, ... Protein Science 28 (7), 1290-1306, 2019 | 22 | 2019 |
Epithelial sodium channel biogenesis and quality control in the early secretory pathway TM Buck, JL Brodsky Current Opinion in Nephrology and Hypertension 27 (5), 364-372, 2018 | 19 | 2018 |
Functional roles of clusters of hydrophobic and polar residues in the epithelial Na+ channel knuckle domain J Chen, EC Ray, ME Yates, TM Buck, JL Brodsky, CL Kinlough, ... Journal of Biological Chemistry 290 (41), 25140-25150, 2015 | 15 | 2015 |
Regulation of the epithelial Na+ channel by paraoxonase-2 S Shi, TM Buck, CL Kinlough, AL Marciszyn, RP Hughey, M Chalfie, ... Journal of Biological Chemistry 292 (38), 15927-15938, 2017 | 14 | 2017 |
Expression of three topologically distinct membrane proteins elicits unique stress response pathways in the yeast Saccharomyces cerevisiae TM Buck, R Jordan, J Lyons-Weiler, JL Adelman, PG Needham, ... Physiological genomics 47 (6), 198-214, 2015 | 12 | 2015 |
The molecular chaperone GRP170 protects against ER stress and acute kidney injury in mice AW Porter, DN Nguyen, DR Clayton, WG Ruiz, SM Mutchler, EC Ray, ... JCI insight 7 (5), 2022 | 11 | 2022 |
Thumb domains of the three epithelial Na+ channel subunits have distinct functions S Sheng, J Chen, A Mukherjee, ME Yates, TM Buck, JL Brodsky, ... Journal of Biological Chemistry 293 (45), 17582-17592, 2018 | 9 | 2018 |
The capture of a disabled proteasome identifies erg25 as a substrate for endoplasmic reticulum associated degradation TM Buck, X Zeng, PS Cantrell, RT Cattley, Z Hasanbasri, ME Yates, ... Molecular & Cellular Proteomics 19 (11), 1896-1909, 2020 | 7 | 2020 |
Escaping the endoplasmic reticulum: why does a molecular chaperone leave home for greener pastures? TM Buck, JL Brodsky The EMBO journal 34 (1), 1-3, 2015 | 7 | 2015 |