Phylogenetic and genetic linkage between novel atypical dual-specificity phosphatases from non-metazoan organisms C Romá-Mateo, A Sacristán-Reviriego, NJ Beresford, JA Caparrós-Martín, ... Molecular Genetics and Genomics 285, 341-354, 2011 | 31 | 2011 |
Wide-ranging effects of the yeast Ptc1 protein phosphatase acting through the MAPK kinase Mkk1 L Tatjer, A Sacristán-Reviriego, C Casado, A González, ... Genetics 202 (1), 141-156, 2016 | 30 | 2016 |
Identification of putative negative regulators of yeast signaling through a screening for protein phosphatases acting on cell wall integrity and mating MAPK pathways A Sacristán-Reviriego, H Martín, M Molina Fungal Genetics and Biology 77, 1-11, 2015 | 27 | 2015 |
The integrity and organization of the human AIPL1 functional domains is critical for its role as a HSP90-dependent co-chaperone for rod PDE6 A Sacristan-Reviriego, J Bellingham, C Prodromou, AN Boehm, A Aichem, ... Human molecular genetics 26 (22), 4465-4480, 2017 | 26 | 2017 |
Distinct docking mechanisms mediate interactions between the Msg5 phosphatase and mating or cell integrity mitogen-activated protein kinases (MAPKs) in Saccharomyces cerevisiae L Palacios, RJ Dickinson, A Sacristán-Reviriego, MP Didmon, MJ Marín, ... Journal of Biological Chemistry 286 (49), 42037-42050, 2011 | 24 | 2011 |
An analog-sensitive version of the protein kinase Slt2 allows identification of novel targets of the yeast cell wall integrity pathway E Alonso-Rodríguez, P Fernández-Piñar, A Sacristán-Reviriego, M Molina, ... Journal of Biological Chemistry 291 (11), 5461-5472, 2016 | 21 | 2016 |
Clinical and functional analyses of AIPL1 variants reveal mechanisms of pathogenicity linked to different forms of retinal degeneration A Sacristan-Reviriego, HM Le, M Georgiou, I Meunier, B Bocquet, ... Scientific reports 10 (1), 17520, 2020 | 16 | 2020 |
The leber congenital amaurosis-linked protein AIPL1 and its critical role in photoreceptors A Sacristan-Reviriego, J van der Spuy Retinal Degenerative Diseases: Mechanisms and Experimental Therapy, 381-386, 2018 | 13 | 2018 |
Investigation of PTC124-mediated translational readthrough in a retinal organoid model of AIPL1-associated Leber congenital amaurosis A Leung, A Sacristan-Reviriego, PRL Perdigão, H Sai, M Georgiou, ... Stem Cell Reports 17 (10), 2187-2202, 2022 | 12 | 2022 |
A conserved non-canonical docking mechanism regulates the binding of dual specificity phosphatases to cell integrity mitogen-activated protein kinases (MAPKs) in budding and … A Sacristán-Reviriego, M Madrid, J Cansado, H Martín, M Molina PLoS One 9 (1), e85390, 2014 | 11 | 2014 |
The ubiquitin-like modifier FAT10 inhibits retinal PDE6 activity and mediates its proteasomal degradation AN Boehm, J Bialas, N Catone, A Sacristan-Reviriego, J van der Spuy, ... Journal of Biological Chemistry 295 (42), 14402-14418, 2020 | 7 | 2020 |
Retinal organoids from an AIPL1 CRISPR/Cas9 knockout Cell line successfully recapitulate the molecular features of LCA4 disease PRL Perdigão, B Ollington, H Sai, A Leung, A Sacristan-Reviriego, ... International Journal of Molecular Sciences 24 (6), 5912, 2023 | 4 | 2023 |
Methods to study protein tyrosine phosphatases acting on yeast MAPKs A Sacristán-Reviriego, M Molina, H Martín Protein Tyrosine Phosphatases: Methods and Protocols, 385-398, 2016 | 4 | 2016 |
Effective AAV-mediated gene replacement therapy in retinal organoids modelling AIPL1-associated LCA4 H Sai, B Ollington, FO Rezek, N Chai, A Lane, T Georgiadis, J Bainbridge, ... Molecular Therapy-Nucleic Acids, 2024 | | 2024 |
Translational readthrough as a potential therapeutic for AIPL1-associated Leber Congenital Amaurosis in a patient-derived iPSC-retinal organoid model A Leung, A Sacristan-Reviriego, PRL Perdigão, H Sai, M Georgiou, ... bioRxiv, 2021.12. 17.473147, 2021 | | 2021 |
Investigation of Ataluren (PTC124) as a potential therapeutic for LCA4 in a patient-derived iPS-retinal organoid model A Leung, A Sacristan-Reviriego, P Perdigao, JWB Bainbridge, ... Investigative Ophthalmology & Visual Science 62 (8), 1671-1671, 2021 | | 2021 |
Determination of AIPL1 variations as disease causing in Leber Congenital Amaurosis patients HM Le, AS Reviriego, J Van Der Spuy Investigative Ophthalmology & Visual Science 59 (9), 3083-3083, 2018 | | 2018 |
Functional assessment of AIPL1 variations identified in Leber Congenital Amaurosis patients AS Reviriego, J Bellingham, C Prodromou, J van der Spuy Investigative Ophthalmology & Visual Science 58 (8), 3597-3597, 2017 | | 2017 |
Mapping the mechanisms of retinal degeneration caused by mutations in the co-chaperone AIPL1 A Sacristan-Reviriego, J Bellingham, M Michaelides, J Bainbridge, ... EMBO Conference: Protein Quality Control: Success and Failure in Health and …, 2017 | | 2017 |
Estudio de la regulación negativa por proteín fosfatasas de las rutas de señalización mediadas por MAPKs de apareamiento e integridad celular en" Saccharomyces cerevisiae" AS Reviriego Universidad Complutense de Madrid, 2014 | | 2014 |