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Xianjun Zhang
Xianjun Zhang
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Cited by
Cited by
Year
Structures of α-synuclein filaments from human brains with Lewy pathology
Y Yang, Y Shi, M Schweighauser, X Zhang, A Kotecha, AG Murzin, ...
Nature 610 (7933), 791-795, 2022
1572022
Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand
X Zhang, F Zhao, Y Wu, J Yang, GW Han, S Zhao, A Ishchenko, L Ye, ...
Nature communications 8 (1), 15383, 2017
1112017
The importance of ligands for G protein-coupled receptor stability
X Zhang, RC Stevens, F Xu
Trends in biochemical sciences 40 (2), 79-87, 2015
902015
Structural and druggability landscape of Frizzled G protein-coupled receptors
X Zhang, S Dong, F Xu
Trends in biochemical sciences 43 (12), 1033-1046, 2018
482018
Visualizing subcellular rearrangements in intact β cells using soft x-ray tomography
KL White, J Singla, V Loconte, JH Chen, A Ekman, L Sun, X Zhang, ...
Science advances 6 (50), eabc8262, 2020
352020
Cryo-EM structure of constitutively active human Frizzled 7 in complex with heterotrimeric Gs
L Xu, B Chen, H Schihada, SC Wright, A Turku, Y Wu, GW Han, ...
Cell research 31 (12), 1311-1314, 2021
272021
Visualizing insulin vesicle neighborhoods in β cells by cryo–electron tomography
X Zhang, SD Carter, J Singla, KL White, PC Butler, RC Stevens, ...
Science Advances 6 (50), eabc8258, 2020
242020
New SNCA mutation and structures of α-synuclein filaments from juvenile-onset synucleinopathy
Y Yang, HJ Garringer, Y Shi, S Lövestam, S Peak-Chew, X Zhang, ...
Acta Neuropathologica 145 (5), 561-572, 2023
172023
A structurally guided dissection-then-evolution strategy for ligand optimization of smoothened receptor
L Ye, K Ding, F Zhao, X Liu, Y Wu, Y Liu, D Xue, F Zhou, X Zhang, ...
MedChemComm 8 (6), 1332-1336, 2017
122017
The structure-based traceless specific fluorescence labeling of the smoothened receptor
D Xue, L Ye, J Zheng, Y Wu, X Zhang, Y Xu, T Li, RC Stevens, F Xu, ...
Organic & Biomolecular Chemistry 17 (25), 6136-6142, 2019
62019
Colocalization strategy unveils an underside binding site in the transmembrane domain of smoothened receptor
F Zhou, K Ding, Y Zhou, Y Liu, X Liu, F Zhao, Y Wu, X Zhang, Q Tan, F Xu, ...
Journal of Medicinal Chemistry 62 (21), 9983-9989, 2019
52019
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