| Membrane transporters in drug development Nature reviews Drug discovery 9 (3), 215-236, 2010 | 3488 | 2010 |
| The resurgence of covalent drugs J Singh, RC Petter, TA Baillie, A Whitty Nature reviews Drug discovery 10 (4), 307-317, 2011 | 1836 | 2011 |
| Drug− protein adducts: an industry perspective on minimizing the potential for drug bioactivation in drug discovery and development DC Evans, AP Watt, DA Nicoll-Griffith, TA Baillie Chemical research in toxicology 17 (1), 3-16, 2004 | 814 | 2004 |
| Structural alert/reactive metabolite concept as applied in medicinal chemistry to mitigate the risk of idiosyncratic drug toxicity: a perspective based on the critical … AF Stepan, DP Walker, J Bauman, DA Price, TA Baillie, AS Kalgutkar, ... Chemical research in toxicology 24 (9), 1345-1410, 2011 | 674 | 2011 |
| Is the role of the small intestine in first-pass metabolism overemphasized? JH Lin, M Chiba, TA Baillie Pharmacological reviews 51 (2), 135-158, 1999 | 511 | 1999 |
| Managing the challenge of chemically reactive metabolites in drug development BK Park, A Boobis, S Clarke, CEP Goldring, D Jones, JG Kenna, ... Nature Reviews Drug Discovery 10 (4), 292-306, 2011 | 482 | 2011 |
| Targeted covalent inhibitors for drug design TA Baillie Angewandte Chemie International Edition 55 (43), 13408-13421, 2016 | 465 | 2016 |
| The use of stable isotopes in pharmacological research TA Baillie Pharmacological Reviews 33 (2), 81-132, 1981 | 408 | 1981 |
| Glucuronidation of statins in animals and humans: a novel mechanism of statin lactonization T Prueksaritanont, R Subramanian, X Fang, B Ma, Y Qiu, JH Lin, ... Drug Metabolism and Disposition 30 (5), 505-512, 2002 | 395 | 2002 |
| Drug metabolites in safety testing TA Baillie, MN Cayen, H Fouda, RJ Gerson, JD Green, SJ Grossman, ... Toxicology and applied pharmacology 182 (3), 188-196, 2002 | 375 | 2002 |
| Studies on the metabolism of troglitazone to reactive intermediates in vitro and in vivo. Evidence for novel biotransformation pathways involving quinone methide formation and … K Kassahun, PG Pearson, W Tang, I McIntosh, K Leung, C Elmore, ... Chemical research in toxicology 14 (1), 62-70, 2001 | 362 | 2001 |
| Mechanistic studies on metabolic interactions between gemfibrozil and statins T Prueksaritanont, JJ Zhao, B Ma, BA Roadcap, C Tang, Y Qiu, L Liu, ... Journal of Pharmacology and Experimental Therapeutics 301 (3), 1042-1051, 2002 | 350 | 2002 |
| Mass spectrometry in the analysis of glutathione conjugates TA Baillie, MR Davis Biological mass spectrometry 22 (6), 319-325, 1993 | 350 | 1993 |
| Cytochrome P-450—Catalyzed Formation of Δ4-VPA, a Toxic Metabolite of Valproic Acid AE Rettie, AW Rettenmeier, WN Howald, TA Baillie Science 235 (4791), 890-893, 1987 | 330 | 1987 |
| Negative ion tandem mass spectrometry for the detection of glutathione conjugates CM Dieckhaus, CL Fernández-Metzler, R King, PH Krolikowski, TA Baillie Chemical research in toxicology 18 (4), 630-638, 2005 | 255 | 2005 |
| Biotransformation of the naturally occurring isothiocyanate sulforaphane in the rat: identification of phase I metabolites and glutathione conjugates K Kassahun, M Davis, P Hu, B Martin, T Baillie Chemical research in toxicology 10 (11), 1228-1233, 1997 | 255 | 1997 |
| Metabolism and toxicity of drugs. Two decades of progress in industrial drug metabolism TA Baillie Chemical research in toxicology 21 (1), 129-137, 2008 | 227 | 2008 |
| Studies on cytochrome P-450-mediated bioactivation of diclofenac in rats and in human hepatocytes: identification of glutathione conjugated metabolites WEI Tang, RA Stearns, SM Bandiera, Y Zhang, C Raab, MP Braun, ... Drug Metabolism and Disposition 27 (3), 365-372, 1999 | 222 | 1999 |
| Roles of human hepatic cytochrome P450s 2C9 and 3A4 in the metabolic activation of diclofenac W Tang, RA Stearns, RW Wang, SHL Chiu, TA Baillie Chemical research in toxicology 12 (2), 192-199, 1999 | 212 | 1999 |
| Extrapolation of diclofenac clearance from in vitro microsomal metabolism data: role of acyl glucuronidation and sequential oxidative metabolism of the acyl glucuronide S Kumar, K Samuel, R Subramanian, MP Braun, RA Stearns, SHL Chiu, ... Journal of Pharmacology and Experimental Therapeutics 303 (3), 969-978, 2002 | 200 | 2002 |
