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Philip Kitchen
Philip Kitchen
Verified email at aston.ac.uk
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Human aquaporins: regulators of transcellular water flow
RE Day, P Kitchen, DS Owen, C Bland, L Marshall, AC Conner, RM Bill, ...
Biochimica et Biophysica Acta (BBA)-General Subjects 1840 (5), 1492-1506, 2014
3682014
Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema
P Kitchen, MM Salman, AM Halsey, C Clarke-Bland, JA MacDonald, ...
Cell 181 (4), 784-799. e19, 2020
3372020
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Ion channels
SPH Alexander, A Mathie, JA Peters, EL Veale, J Striessnig, E Kelly, ...
British Journal of Pharmacology 178, S157-S245, 2021
2312021
Beyond water homeostasis: diverse functional roles of mammalian aquaporins
P Kitchen, RE Day, MM Salman, MT Conner, RM Bill, AC Conner
Biochimica et Biophysica Acta (BBA)-General Subjects 1850 (12), 2410-2421, 2015
1512015
Emerging roles for dynamic aquaporin-4 subcellular relocalization in CNS water homeostasis
MM Salman, P Kitchen, A Halsey, MX Wang, S Tornroth-Horsefield, ...
Brain, 2021
1302021
Inhibitors of Mammalian Aquaporin Water Channels
M Abir-Awan, P Kitchen, MM Salman, MT Conner, AC Conner, RM Bill
International journal of molecular sciences 20 (7), 1589, 2019
1212019
Identification and molecular mechanisms of the rapid tonicity-induced relocalization of the aquaporin 4 channel
P Kitchen, RE Day, LHJ Taylor, MM Salman, RM Bill, MT Conner, ...
Journal of Biological Chemistry 290 (27), 16873-16881, 2015
1042015
Advances in Applying Computer-Aided Drug Design for Neurodegenerative Diseases
MM Salman, Z Al-Obaidi, P Kitchen, A Loreto, RM Bill, R Wade-Martins
International Journal of Molecular Sciences 22 (9), 4688, 2021
932021
Hypothermia increases aquaporin 4 (AQP4) plasma membrane abundance in human primary cortical astrocytes via a calcium/transient receptor potential vanilloid 4 (TRPV4)‐and …
MM Salman, P Kitchen, MN Woodroofe, JE Brown, RM Bill, AC Conner, ...
European Journal of Neuroscience 46 (9), 2542-2547, 2017
912017
HHEX is a transcriptional regulator of the VEGFC/FLT4/PROX1 signaling axis during vascular development
S Gauvrit, A Villasenor, B Strilic, P Kitchen, MM Collins, R Marín-Juez, ...
Nature communications 9 (1), 1-14, 2018
752018
Recent breakthroughs and future directions in drugging aquaporins
MM Salman, P Kitchen, AJ Yool, RM Bill
Trends in pharmacological sciences 43 (1), 30-42, 2022
692022
Aquaporin 4 and glymphatic flow have central roles in brain fluid homeostasis
MM Salman, P Kitchen, JJ Iliff, RM Bill
Nature Reviews Neuroscience 22 (10), 650-651, 2021
662021
Signaling mechanisms and pharmacological modulators governing diverse aquaporin functions in human health and disease
K Wagner, L Unger, MM Salman, P Kitchen, RM Bill, AJ Yool
International Journal of Molecular Sciences 23 (3), 1388, 2022
622022
Plasma membrane abundance of human aquaporin 5 is dynamically regulated by multiple pathways
P Kitchen, F Öberg, J Sjöhamn, K Hedfalk, RM Bill, AC Conner, ...
PloS one 10 (11), e0143027, 2015
622015
Transcriptome analysis suggests a role for the differential expression of cerebral aquaporins and the MAPK signalling pathway in human temporal lobe epilepsy
MM Salman, MA Sheilabi, D Bhattacharyya, P Kitchen, AC Conner, ...
European Journal of Neuroscience 46 (5), 2121-2132, 2017
612017
Transcriptome analysis of gene expression provides new insights into the effect of mild therapeutic hypothermia on primary human cortical astrocytes cultured under hypoxia
MM Salman, P Kitchen, MN Woodroofe, RM Bill, AC Conner, PR Heath, ...
Frontiers in cellular neuroscience 11, 386, 2017
602017
Water channel pore size determines exclusion properties but not solute selectivity
P Kitchen, MM Salman, SU Pickel, J Jennings, S Törnroth-Horsefield, ...
Scientific Reports 9 (1), 20369, 2019
512019
Molecular mechanisms governing aquaporin relocalisation
A Markou, L Unger, M Abir-Awan, A Saadallah, A Halsey, Z Balklava, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1864 (4), 183853, 2022
492022
CX-4945 Induces Methuosis in Cholangiocarcinoma Cell Lines by a CK2-Independent Mechanism
J Lertsuwan, K Lertsuwan, A Sawasdichai, N Tasnawijitwong, K Lee, ...
Cancers 10 (9), 283, 2018
462018
Structural determinants of oligomerization of the aquaporin-4 channel
P Kitchen, MT Conner, RM Bill, AC Conner
Journal of Biological Chemistry 291 (13), 6858-6871, 2016
372016
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