| Bromodomain biology and drug discovery N Zaware, MM Zhou Nature structural & molecular biology 26 (10), 870-879, 2019 | 184 | 2019 |
| Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth J Sangodkar, A Perl, R Tohme, J Kiselar, DB Kastrinsky, N Zaware, ... The Journal of clinical investigation 127 (6), 2081-2090, 2017 | 180 | 2017 |
| Selective PP2A enhancement through biased heterotrimer stabilization D Leonard, W Huang, S Izadmehr, CM O’Connor, DD Wiredja, Z Wang, ... Cell 181 (3), 688-701. e16, 2020 | 126 | 2020 |
| Single Agents with Designed Combination Chemotherapy Potential: Synthesis and Evaluation of Substituted Pyrimido[4,5-b]indoles as Receptor Tyrosine Kinase … A Gangjee, N Zaware, S Raghavan, M Ihnat, S Shenoy, RL Kisliuk Journal of medicinal chemistry 53 (4), 1563-1578, 2010 | 83 | 2010 |
| Reengineered tricyclic anti-cancer agents DB Kastrinsky, J Sangodkar, N Zaware, S Izadmehr, NS Dhawan, G Narla, ... Bioorganic & medicinal chemistry 23 (19), 6528-6534, 2015 | 82 | 2015 |
| Small-molecule activators of protein phosphatase 2A for the treatment of castration-resistant prostate cancer K McClinch, RA Avelar, D Callejas, S Izadmehr, D Wiredja, A Perl, ... Cancer research 78 (8), 2065-2080, 2018 | 72 | 2018 |
| SAFE AND SCALABLE PREPARATION OF BARLUENGA’S REAGENT PW Justin M. Chalker, Amber L. Thompson, and Benjamin G. Davis., Nilesh Zaware Organic Syntheses 87, 288-298, 2010 | 48 | 2010 |
| AG311, a small molecule inhibitor of complex I and hypoxia-induced HIF-1α stabilization A Bastian, S Matsuzaki, KM Humphries, GA Pharaoh, A Doshi, N Zaware, ... Cancer letters 388, 149-157, 2017 | 45 | 2017 |
| Chemical modulators for epigenome reader domains as emerging epigenetic therapies for cancer and inflammation N Zaware, MM Zhou Current opinion in chemical biology 39, 116-125, 2017 | 43 | 2017 |
| Recent advances in dibenzo [b, f][1, 4] oxazepine synthesis N Zaware, M Ohlmeyer Heterocyclic Communications 20 (5), 251-256, 2014 | 31 | 2014 |
| Monotherapy efficacy of blood–brain barrier permeable small molecule reactivators of protein phosphatase 2A in glioblastoma J Merisaari, OV Denisova, M Doroszko, V Le Joncour, P Johansson, ... Brain Communications 2 (1), fcaa002, 2020 | 30 | 2020 |
| Discovery of Potent and Selective Inhibitors of Toxoplasma gondii Thymidylate Synthase for Opportunistic Infections N Zaware, H Sharma, J Yang, RKV Devambatla, SF Queener, ... ACS medicinal chemistry letters 4 (12), 1148-1151, 2013 | 30 | 2013 |
| Synthesis and biological activity of 5-chloro-N4-substituted phenyl-9H-pyrimido [4, 5-b] indole-2, 4-diamines as vascular endothelial growth factor receptor-2 inhibitors and … A Gangjee, N Zaware, S Raghavan, BC Disch, JE Thorpe, A Bastian, ... Bioorganic & medicinal chemistry 21 (7), 1857-1864, 2013 | 29 | 2013 |
| N4-(3-Bromophenyl)-7-(substituted benzyl) pyrrolo [2, 3-d] pyrimidines as potent multiple receptor tyrosine kinase inhibitors: Design, synthesis, and in vivo evaluation A Gangjee, N Zaware, S Raghavan, J Yang, JE Thorpe, MA Ihnat Bioorganic & medicinal chemistry 20 (7), 2444-2454, 2012 | 28 | 2012 |
| Synthesis of N4-(substituted phenyl)-N4-alkyl/desalkyl-9H-pyrimido [4, 5-b] indole-2, 4-diamines and identification of new microtubule disrupting compounds that are effective … A Gangjee, N Zaware, RKV Devambatla, S Raghavan, CD Westbrook, ... Bioorganic & medicinal chemistry 21 (4), 891-902, 2013 | 26 | 2013 |
| Synthesis and evaluation of 5-(arylthio)-9H-pyrimido [4, 5-b] indole-2, 4-diamines as receptor tyrosine kinase and thymidylate synthase inhibitors and as antitumor agents N Zaware, R Kisliuk, A Bastian, MA Ihnat, A Gangjee Bioorganic & medicinal chemistry letters 27 (7), 1602-1607, 2017 | 16 | 2017 |
| Design, synthesis, and structure–activity relationships of pyrimido [4, 5-b] indole-4-amines as microtubule depolymerizing agents that are effective against multidrug resistant … RKV Devambatla, W Li, N Zaware, S Choudhary, E Hamel, SL Mooberry, ... Bioorganic & medicinal chemistry letters 27 (15), 3423-3430, 2017 | 15 | 2017 |
| Regulated induced proximity targeting chimeras (RIPTACs): a novel heterobifunctional small molecule therapeutic strategy for killing cancer cells selectively K Raina, CD Forbes, R Stronk, JP Rappi Jr, KJ Eastman, SW Gerritz, X Yu, ... bioRxiv, 2023 | 13 | 2023 |
| Copper-Catalyzed Synthesis of Dibenzo [b, f] imidazo [1, 2-d][1, 4] oxazepine Derivatives via a Double Ullmann Coupling Reaction XY Chen, ZH Li, JQ Liu, XS Wang Synthesis 51 (07), 1662-1668, 2019 | 13 | 2019 |
| Diversity-oriented synthesis of a library of substituted tetrahydropyrones using oxidative carbon-hydrogen bond activation and click chemistry N Zaware, MG LaPorte, R Farid, L Liu, P Wipf, PE Floreancig Molecules 16 (5), 3648-3662, 2011 | 10 | 2011 |
Goutham Narla - Chief, Division of Ge...University of MichiganVerified email at med.umich.edu
