Chk1 is an essential kinase that is regulated by Atr and required for the G2/M DNA damage checkpoint Q Liu, S Guntuku, XS Cui, S Matsuoka, D Cortez, K Tamai, G Luo, ... Genes & development 14 (12), 1448-1459, 2000 | 2145 | 2000 |
R2D2, a bridge between the initiation and effector steps of the Drosophila RNAi pathway Q Liu, TA Rand, S Kalidas, F Du, HE Kim, DP Smith, X Wang Science 301 (5641), 1921-1925, 2003 | 958 | 2003 |
Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways. Y Sanchez, BA Desany, WJ Jones, Q Liu, B Wang, SJ Elledge Science 271, 357-360, 1996 | 794 | 1996 |
ATP-dependent human RISC assembly pathways M Yoda, T Kawamata, Z Paroo, X Ye, S Iwasaki, Q Liu, Y Tomari Nature structural & molecular biology 17 (1), 17-23, 2010 | 479 | 2010 |
Phosphorylation of the human microRNA-generating complex mediates MAPK/Erk signaling Z Paroo, X Ye, S Chen, Q Liu Cell 139 (1), 112-122, 2009 | 464 | 2009 |
Dicer-1 and R3D1-L catalyze microRNA maturation in Drosophila F Jiang, X Ye, X Liu, L Fincher, D McKearin, Q Liu Genes & development 19 (14), 1674-1679, 2005 | 396 | 2005 |
The univector plasmid-fusion system, a method for rapid construction of recombinant DNA without restriction enzymes Q Liu, MZ Li, D Leibham, D Cortez, SJ Elledge Current biology 8 (24), S1, 1998 | 374 | 1998 |
C3PO, an endoribonuclease that promotes RNAi by facilitating RISC activation Y Liu, X Ye, F Jiang, C Liang, D Chen, J Peng, LN Kinch, NV Grishin, ... Science 325 (5941), 750-753, 2009 | 300 | 2009 |
A small molecule enhances RNA interference and promotes microRNA processing G Shan, Y Li, J Zhang, W Li, KE Szulwach, R Duan, MA Faghihi, AM Khalil, ... Nature biotechnology 26 (8), 933-940, 2008 | 282 | 2008 |
Chk1 is haploinsufficient for multiple functions critical to tumor suppression MH Lam, Q Liu, SJ Elledge, JM Rosen Cancer cell 6 (1), 45-59, 2004 | 282 | 2004 |
Forward-genetics analysis of sleep in randomly mutagenized mice H Funato, C Miyoshi, T Fujiyama, T Kanda, M Sato, Z Wang, J Ma, ... Nature 539 (7629), 378-383, 2016 | 275 | 2016 |
Dicer-2 and R2D2 coordinately bind siRNA to promote assembly of the siRISC complexes X Liu, F Jiang, S Kalidas, D Smith, Q Liu Rna 12 (8), 1514-1520, 2006 | 240 | 2006 |
Biochemical principles of small RNA pathways Q Liu, Z Paroo Annual review of biochemistry 79, 295-319, 2010 | 229 | 2010 |
The miRNA pathway intrinsically controls self-renewal of Drosophila germline stem cells JK Park, X Liu, TJ Strauss, DM McKearin, Q Liu Current Biology 17 (6), 533-538, 2007 | 214 | 2007 |
Quantitative phosphoproteomic analysis of the molecular substrates of sleep need Z Wang, J Ma, C Miyoshi, Y Li, M Sato, Y Ogawa, T Lou, C Ma, X Gao, ... Nature 558 (7710), 435-439, 2018 | 203 | 2018 |
Structure of C3PO and mechanism of human RISC activation X Ye, N Huang, Y Liu, Z Paroo, C Huerta, P Li, S Chen, Q Liu, H Zhang Nature structural & molecular biology 18 (6), 650-657, 2011 | 183 | 2011 |
Induction of necrotic cell death by oxidative stress in retinal pigment epithelial cells J Hanus, H Zhang, Z Wang, Q Liu, Q Zhou, S Wang Cell death & disease 4 (12), e965-e965, 2013 | 163 | 2013 |
Dicer's helicase domain discriminates dsRNA termini to promote an altered reaction mode NC Welker, TS Maity, X Ye, PJ Aruscavage, AA Krauchuk, Q Liu, BL Bass Molecular cell 41 (5), 589-599, 2011 | 158 | 2011 |
Dicer-1, but not Loquacious, is critical for assembly of miRNA-induced silencing complexes X Liu, JK Park, F Jiang, Y Liu, D McKearin, Q Liu Rna 13 (12), 2324-2329, 2007 | 96 | 2007 |
Sjögren syndrome antigen B (SSB)/La promotes global microRNA expression by binding microRNA precursors through stem-loop recognition C Liang, K Xiong, KE Szulwach, Y Zhang, Z Wang, J Peng, M Fu, P Jin, ... Journal of Biological Chemistry 288 (1), 723-736, 2013 | 91 | 2013 |