BMI1 regulates PRC1 architecture and activity through homo-and hetero-oligomerization F Gray, HJ Cho, S Shukla, S He, A Harris, B Boytsov, Ł Jaremko, ... Nature communications 7, 13343, 2016 | 70 | 2016 |
An evolution-based approach to de novo protein design and case study on Mycobacterium tuberculosis P Mitra, D Shultis, JR Brender, J Czajka, D Marsh, F Gray, T Cierpicki, ... PLoS computational biology 9 (10), e1003298, 2013 | 49 | 2013 |
Small-molecule inhibitors targeting Polycomb repressive complex 1 RING domain S Shukla, W Ying, F Gray, Y Yao, ML Simes, Q Zhao, H Miao, HJ Cho, ... Nature chemical biology 17 (7), 784-793, 2021 | 33 | 2021 |
Changing the Apoptosis Pathway through Evolutionary Protein Design D Shultis, P Mitra, X Huang, J Johnson, NA Khattak, F Gray, C Piper, ... Journal of molecular biology 431 (4), 825-841, 2019 | 18 | 2019 |
Detection of disordered regions in globular proteins using 13C‐detected NMR FLV Gray, MJ Murai, J Grembecka, T Cierpicki Protein Science 21 (12), 1954-1960, 2012 | 13 | 2012 |
Small molecule Ring1B-Bmi1 inhibitor attenuates PRC1 E3 ligase activity and targets leukemia stem cells self-renewal S Shukla, F Gray, W Ying, H Cho, Q Zhao, H Miao, T Purohit, M Guzman, ... Clinical Cancer Research 23 (24 Supplement), 50-50, 2017 | 1 | 2017 |
Small molecule inhibitors of ring1B-Bmi1 E3 ligase target polycomb repressive complex 1 activity and regulate cell proliferation S Shukla, Q Zhao, W Ying, F Gray, K Vandenberg, G Lund, B Boytsov, ... Cancer Research 75 (15 Supplement), 3520-3520, 2015 | 1 | 2015 |
Targeting Polycomb Repressive Complex 1 with small-molecule inhibitors as a potential therapeutic approach to combat leukemia ML Simes, Y Yao, SR Park, T Purohit, H Miao, X Zhang, W Ying, F Gray, ... Cancer Research 83 (7_Supplement), 6286-6286, 2023 | | 2023 |
PRC1 INHIBITORS AND METHODS OF TREATMENT THEREWITH T Cierpicki, J Grembecka, W Ying, Y Yao, F Gray, Q Zhao US Patent App. 16/434,508, 2020 | | 2020 |
Novel Ring1B-Bmi1 small molecule inhibitors target leukemia stem cells S Shukla, F Gray, W Ying, H Cho, Q Zhao, H Miao, T Purohit, ... Cancer Research 76 (14 Supplement), 4690-4690, 2016 | | 2016 |
Dissecting BMI1 Protein-Protein Interactions Through Chemical Biology. F Gray | | 2015 |