| Mitophagy protects β cells from inflammatory damage in diabetes V Sidarala, GL Pearson, VS Parekh, B Thompson, L Christen, ... JCI insight 5 (24), 2020 | 75 | 2020 |
| Deletion of PKCε selectively enhances the amplifying pathways of glucose-stimulated insulin secretion via increased lipolysis in mouse β-cells J Cantley, JG Burchfield, GL Pearson, C Schmitz-Peiffer, M Leitges, ... Diabetes 58 (8), 1826-1834, 2009 | 65 | 2009 |
| Clec16a, Nrdp1, and USP8 form a ubiquitin-dependent tripartite complex that regulates β-cell mitophagy G Pearson, B Chai, T Vozheiko, X Liu, M Kandarpa, RC Piper, ... Diabetes 67 (2), 265-277, 2018 | 60 | 2018 |
| Lysosomal acid lipase and lipophagy are constitutive negative regulators of glucose-stimulated insulin secretion from pancreatic beta cells GL Pearson, N Mellett, KY Chu, J Cantley, A Davenport, P Bourbon, ... Diabetologia 57, 129-139, 2014 | 49 | 2014 |
| Mitofusin 1 and 2 regulation of mitochondrial DNA content is a critical determinant of glucose homeostasis V Sidarala, J Zhu, E Levi-D’Ancona, GL Pearson, EC Reck, EM Walker, ... Nature communications 13 (1), 2340, 2022 | 39 | 2022 |
| Deletion of protein kinase Cδ in mice modulates stability of inflammatory genes and protects against cytokine-stimulated beta cell death in vitro and in vivo J Cantley, E Boslem, DR Laybutt, DV Cordery, G Pearson, L Carpenter, ... Diabetologia 54, 380-389, 2011 | 37 | 2011 |
| The E3 ubiquitin ligase parkin is dispensable for metabolic homeostasis in murine pancreatic β cells and adipocytes CAS Corsa, GL Pearson, A Renberg, MM Askar, T Vozheiko, ... Journal of Biological Chemistry 294 (18), 7296-7307, 2019 | 36 | 2019 |
| A selective look at autophagy in pancreatic β-cells GL Pearson, MA Gingerich, EM Walker, TJ Biden, SA Soleimanpour Diabetes 70 (6), 1229-1241, 2021 | 27 | 2021 |
| A comprehensive lipidomic screen of pancreatic β-cells using mass spectroscopy defines novel features of glucose-stimulated turnover of neutral lipids, sphingolipids and … GL Pearson, N Mellett, KY Chu, E Boslem, PJ Meikle, TJ Biden Molecular metabolism 5 (6), 404-414, 2016 | 25 | 2016 |
| A ubiquitin-dependent mitophagy complex maintains mitochondrial function and insulin secretion in beta cells G Pearson, SA Soleimanpour Autophagy 14 (7), 1160-1161, 2018 | 20 | 2018 |
| An intrinsically disordered protein region encoded by the human disease gene CLEC16A regulates mitophagy MA Gingerich, X Liu, B Chai, GL Pearson, MP Vincent, T Stromer, J Zhu, ... Autophagy 19 (2), 525-543, 2023 | 6 | 2023 |
| Mitophagy protects beta cells from inflammatory damage in diabetes. JCI Insight. 2020; 5: e141138 V Sidarala, GL Pearson, VS Parekh, B Thompson, L Christen, ... | 6 | |
| Visualization of endogenous mitophagy complexes in situ in human pancreatic beta cells utilizing proximity ligation assay G Pearson, SA Soleimanpour JoVE (Journal of Visualized Experiments), e59398, 2019 | 4 | 2019 |
| 37-OR: Mitofusins 1 and 2 Collaborate to Fuel Pancreatic Beta-Cell Insulin Release via Regulation of Both Mitochondrial Structure and DNA Content V Sidarala, J Zhu, G Pearson, S Soleimanpour Diabetes 70 (Supplement_1), 2021 | 3 | 2021 |
| The human disease gene CLEC16A encodes an intrinsically disordered protein region required for mitochondrial quality control MA Gingerich, X Liu, B Chai, GL Pearson, MP Vincent, T Stromer, J Zhu, ... bioRxiv, 2021.09. 03.458272, 2021 | 1 | 2021 |
| TOLLIP resolves lipid-induced EIF2 signaling in alveolar macrophages for durable Mycobacterium tuberculosis protection S Venkatasubramanian, C Plumlee, K Dill-McFarland, GL Pearson, ... bioRxiv, 2020.08. 24.263624, 2020 | 1 | 2020 |
| TOLLIP inhibits lipid accumulation and the integrated stress response in alveolar macrophages to control Mycobacterium tuberculosis infection S Venkatasubramanian, CR Plumlee, KA Dill-McFarland, SB Cohen, ... Nature Microbiology, 1-15, 2024 | | 2024 |
| Retrograde mitochondrial signaling governs the identity and maturity of metabolic tissues GL Pearson, EM Walker, N Lawlor, A Lietzke, V Sidarala, J Zhu, T Stromer, ... bioRxiv, 2022.08. 02.502357, 2022 | | 2022 |
| Tuberculosis resistance protein TOLLIP controls immune pathology by resolving the integrated stress response in alveolar macrophages. S Venkatasubramanian, C Plumlee, K Dill-McFarland, G Pearson, ... | | 2022 |
| 175-OR: The Mitochondrial Life Cycle Determines ß-Cell Maturity through Activation of the Integrated Stress Response G Pearson, N Lawlor, J Zhu, EM Walker, EC Reck, ML Stitzel, ... Diabetes 70 (Supplement_1), 2021 | | 2021 |
