The C9orf72 repeat expansion disrupts nucleocytoplasmic transport K Zhang, CJ Donnelly, AR Haeusler, JC Grima, JB Machamer, ... Nature 525 (7567), 56-61, 2015 | 1015 | 2015 |
Glial lipid droplets and ROS induced by mitochondrial defects promote neurodegeneration L Liu, K Zhang, H Sandoval, S Yamamoto, M Jaiswal, E Sanz, Z Li, J Hui, ... Cell 160 (1), 177-190, 2015 | 728 | 2015 |
A drosophila genetic resource of mutants to study mechanisms underlying human genetic diseases S Yamamoto, M Jaiswal, WL Charng, T Gambin, E Karaca, G Mirzaa, ... Cell 159 (1), 200-214, 2014 | 399 | 2014 |
Stress granule assembly disrupts nucleocytoplasmic transport K Zhang, JG Daigle, KM Cunningham, AN Coyne, K Ruan, JC Grima, ... Cell 173 (4), 958-971. e17, 2018 | 347 | 2018 |
Mutant huntingtin disrupts the nuclear pore complex JC Grima, JG Daigle, N Arbez, KC Cunningham, K Zhang, J Ochaba, ... Neuron 94 (1), 93-107. e6, 2017 | 316 | 2017 |
Ubiquitination of G3BP1 mediates stress granule disassembly in a context-specific manner Y Gwon, BA Maxwell, RM Kolaitis, P Zhang, HJ Kim, JP Taylor Science 372 (6549), eabf6548, 2021 | 155 | 2021 |
Probing Mechanisms That Underlie Human Neurodegenerative Diseases in Drosophila M Jaiswal, H Sandoval, K Zhang, V Bayat, HJ Bellen Annual review of genetics 46, 371-396, 2012 | 117 | 2012 |
Mitochondrial fusion but not fission regulates larval growth and synaptic development through steroid hormone production H Sandoval, CK Yao, K Chen, M Jaiswal, T Donti, YQ Lin, V Bayat, ... Elife 3, e03558, 2014 | 111 | 2014 |
A mutation in EGF repeat-8 of Notch discriminates between Serrate/Jagged and Delta family ligands S Yamamoto, WL Charng, NA Rana, S Kakuda, M Jaiswal, V Bayat, ... Science 338 (6111), 1229-1232, 2012 | 107 | 2012 |
Crag is a GEF for Rab11 required for rhodopsin trafficking and maintenance of adult photoreceptor cells B Xiong, V Bayat, M Jaiswal, K Zhang, H Sandoval, WL Charng, T Li, ... PLoS biology 10 (12), e1001438, 2012 | 100 | 2012 |
Ubiquitination is essential for recovery of cellular activities after heat shock BA Maxwell, Y Gwon, A Mishra, J Peng, H Nakamura, K Zhang, HJ Kim, ... Science 372 (6549), eabc3593, 2021 | 95 | 2021 |
The retromer complex is required for rhodopsin recycling and its loss leads to photoreceptor degeneration S Wang, KL Tan, MA Agosto, B Xiong, S Yamamoto, H Sandoval, ... PLoS biology 12 (4), e1001847, 2014 | 78 | 2014 |
Large-scale identification of chemically induced mutations in Drosophila melanogaster NA Haelterman, L Jiang, Y Li, V Bayat, H Sandoval, B Ugur, KL Tan, ... Genome research 24 (10), 1707-1718, 2014 | 76 | 2014 |
A reference human induced pluripotent stem cell line for large-scale collaborative studies CB Pantazis, A Yang, E Lara, JA McDonough, C Blauwendraat, L Peng, ... Cell Stem Cell 29 (12), 1685-1702. e22, 2022 | 73 | 2022 |
The C8ORF38 homologue Sicily is a cytosolic chaperone for a mitochondrial complex I subunit K Zhang, Z Li, M Jaiswal, V Bayat, B Xiong, H Sandoval, WL Charng, ... Journal of Cell Biology 200 (6), 807-820, 2013 | 64 | 2013 |
WAC regulates mTOR activity by acting as an adaptor for the TTT and Pontin/Reptin complexes G David-Morrison, Z Xu, YN Rui, WL Charng, M Jaiswal, S Yamamoto, ... Developmental cell 36 (2), 139-151, 2016 | 58 | 2016 |
Drosophila Tempura, a Novel Protein Prenyltransferase α Subunit, Regulates Notch Signaling Via Rab1 and Rab11 WL Charng, S Yamamoto, M Jaiswal, V Bayat, B Xiong, K Zhang, ... PLoS biology 12 (1), e1001777, 2014 | 54 | 2014 |
FIG4 regulates lysosome membrane homeostasis independent of phosphatase function R Bharadwaj, KM Cunningham, K Zhang, TE Lloyd Human molecular genetics 25 (4), 681-692, 2016 | 51 | 2016 |
TFEB/Mitf links impaired nuclear import to autophagolysosomal dysfunction in C9-ALS KM Cunningham, K Maulding, K Ruan, M Senturk, JC Grima, H Sung, ... Elife 9, e59419, 2020 | 47 | 2020 |
Nucleocytoplasmic transport in C9orf72-mediated ALS/FTD K Zhang, JC Grima, JD Rothstein, TE Lloyd Nucleus 7 (2), 132-137, 2016 | 36 | 2016 |