Crystal structure of a voltage-gated sodium channel in two potentially inactivated states J Payandeh, TM Gamal El-Din, T Scheuer, N Zheng, WA Catterall Nature 486 (7401), 135-139, 2012 | 581 | 2012 |
Structural basis for Ca2+ selectivity of a voltage-gated calcium channel L Tang*, TM Gamal El-Din*, J Payandeh, GQ Martinez, TM Heard, ... Nature, * First co-authors 505 (7481), 56-61, 2014 | 368 | 2014 |
Structure of the cardiac sodium channel D Jiang, H Shi, L Tonggu, TM Gamal El-Din, MJ Lenaeus, Y Zhao, ... Cell 180 (1), 122-134. e10, 2020 | 241 | 2020 |
Structure and pharmacology of voltage-gated sodium and calcium channels WA Catterall, MJ Lenaeus, TM Gamal El-Din Annual review of pharmacology and toxicology 60, 2019 | 207 | 2019 |
Structural basis for inhibition of a voltage-gated Ca2+ channel by Ca2+ antagonist drugs L Tang, TM Gamal El-Din, TM Swanson, DC Pryde, T Scheuer, N Zheng, ... Nature, 2016 | 202 | 2016 |
Resting-State structure and gating mechanism of a Voltage-Gated sodium channel G Wisedchaisri, L Tonggu, E McCord, TM Gamal El-Din, L Wang, N Zheng, ... Cell 178 (4), 993-1003. e12, 2019 | 153 | 2019 |
Structures of closed and open states of a voltage-gated sodium channel MJ Lenaeusa, TM Gamal El-Din, C Ing, K Ramanadanea, R Pomèsc, ... PNAS, 2017 | 149 | 2017 |
Computational design of transmembrane pores C Xu, P Lu, TM Gamal El-Din, XY Pei, MC Johnson, A Uyeda, MJ Bick, ... Nature, 1-6, 2020 | 141 | 2020 |
Fenestrations control resting-state block of a voltage-gated sodium channel TM Gamal El-Din, MJ Lenaeus, N Zheng, WA Catterall PNAS, 201814928, 2018 | 96 | 2018 |
Structural basis for gating pore current in periodic paralysis D Jiang*, TM Gamal El-Din*, C Ing, P Lu, R Pomès, N Zheng, WA Catterall Nature, * First co-authors, 2018 | 75 | 2018 |
Structural basis for voltage-sensor trapping of the cardiac sodium channel by a deathstalker scorpion toxin D Jiang, L Tonggu, TM Gamal El-Din, R Banh, R Pomès, N Zheng, ... Nature Communications 12 (1), 1-13, 2021 | 63 | 2021 |
Open-state structure and pore gating mechanism of the cardiac sodium channel D Jiang, R Banh, TM Gamal El-Din, L Tonggu, MJ Lenaeus, R Pomès, ... Cell, 2021 | 56 | 2021 |
Double gaps along Shaker S4 demonstrate omega currents at three different closed states TM Gamal El-Din, H Heldstab, C Lehmann, NG Greeff Channels 4 (2), 93-100, 2010 | 51 | 2010 |
A gating charge interaction required for late slow inactivation of the bacterial sodium channel NavAb TM Gamal El-Din, GQ Martinez, J Payandeh, T Scheuer, WA Catterall The Journal of general physiology 142 (3), 181-190, 2013 | 47 | 2013 |
Structural Basis for High-Affinity Trapping of the Nav1. 7 Channel in Its Resting State by Tarantula Toxin G Wisedchaisri, L Tonggu, TM Gamal El-Din, E McCord, N Zheng, ... Molecular Cell, 2020 | 46 | 2020 |
Structural Basis for Diltiazem Block of a Voltage-gated Ca2+ Channel L Tang, TM Gamal El-Din, MJ Lenaeus, N Zheng, WA Catterall Molecular Pharmacology 96 (4), 485-492, 2019 | 46 | 2019 |
Tracking S4 movement by gating pore currents in the bacterial sodium channel NaChBac TM Gamal El-Din, T Scheuer, WA Catterall The Journal of general physiology 144 (2), 147-157, 2014 | 30 | 2014 |
Molecular dissection of multiphase inactivation of the bacterial sodium channel NaVAb TM Gamal El-Din, MJ Lenaeus, K Ramanadane, N Zheng, WA Catterall The Journal of General Physiology, jgp. 201711884, 2018 | 22 | 2018 |
Autism-associated mutations in KV7 channels induce gating pore current TM Gamal El-Din, T Lantin, CW Tschumi, B Juarez, M Quinlan, ... Proceedings of the National Academy of Sciences 118 (45), 2021 | 17 | 2021 |
Druggability of Voltage-gated Sodium Channels–Exploring Old and New Drug Receptor Sites G Wisedchaisri, TM Gamal El-Din Frontiers in Pharmacology, 903, 2022 | 15 | 2022 |