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Tamer M. Gamal El-Din
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Year
Crystal structure of a voltage-gated sodium channel in two potentially inactivated states
J Payandeh, TM Gamal El-Din, T Scheuer, N Zheng, WA Catterall
Nature 486 (7401), 135-139, 2012
5812012
Structural basis for Ca2+ selectivity of a voltage-gated calcium channel
L Tang*, TM Gamal El-Din*, J Payandeh, GQ Martinez, TM Heard, ...
Nature, * First co-authors 505 (7481), 56-61, 2014
3682014
Structure of the cardiac sodium channel
D Jiang, H Shi, L Tonggu, TM Gamal El-Din, MJ Lenaeus, Y Zhao, ...
Cell 180 (1), 122-134. e10, 2020
2412020
Structure and pharmacology of voltage-gated sodium and calcium channels
WA Catterall, MJ Lenaeus, TM Gamal El-Din
Annual review of pharmacology and toxicology 60, 2019
2072019
Structural basis for inhibition of a voltage-gated Ca2+ channel by Ca2+ antagonist drugs
L Tang, TM Gamal El-Din, TM Swanson, DC Pryde, T Scheuer, N Zheng, ...
Nature, 2016
2022016
Resting-State structure and gating mechanism of a Voltage-Gated sodium channel
G Wisedchaisri, L Tonggu, E McCord, TM Gamal El-Din, L Wang, N Zheng, ...
Cell 178 (4), 993-1003. e12, 2019
1532019
Structures of closed and open states of a voltage-gated sodium channel
MJ Lenaeusa, TM Gamal El-Din, C Ing, K Ramanadanea, R Pomèsc, ...
PNAS, 2017
1492017
Computational design of transmembrane pores
C Xu, P Lu, TM Gamal El-Din, XY Pei, MC Johnson, A Uyeda, MJ Bick, ...
Nature, 1-6, 2020
1412020
Fenestrations control resting-state block of a voltage-gated sodium channel
TM Gamal El-Din, MJ Lenaeus, N Zheng, WA Catterall
PNAS, 201814928, 2018
962018
Structural basis for gating pore current in periodic paralysis
D Jiang*, TM Gamal El-Din*, C Ing, P Lu, R Pomès, N Zheng, WA Catterall
Nature, * First co-authors, 2018
752018
Structural basis for voltage-sensor trapping of the cardiac sodium channel by a deathstalker scorpion toxin
D Jiang, L Tonggu, TM Gamal El-Din, R Banh, R Pomès, N Zheng, ...
Nature Communications 12 (1), 1-13, 2021
632021
Open-state structure and pore gating mechanism of the cardiac sodium channel
D Jiang, R Banh, TM Gamal El-Din, L Tonggu, MJ Lenaeus, R Pomès, ...
Cell, 2021
562021
Double gaps along Shaker S4 demonstrate omega currents at three different closed states
TM Gamal El-Din, H Heldstab, C Lehmann, NG Greeff
Channels 4 (2), 93-100, 2010
512010
A gating charge interaction required for late slow inactivation of the bacterial sodium channel NavAb
TM Gamal El-Din, GQ Martinez, J Payandeh, T Scheuer, WA Catterall
The Journal of general physiology 142 (3), 181-190, 2013
472013
Structural Basis for High-Affinity Trapping of the Nav1. 7 Channel in Its Resting State by Tarantula Toxin
G Wisedchaisri, L Tonggu, TM Gamal El-Din, E McCord, N Zheng, ...
Molecular Cell, 2020
462020
Structural Basis for Diltiazem Block of a Voltage-gated Ca2+ Channel
L Tang, TM Gamal El-Din, MJ Lenaeus, N Zheng, WA Catterall
Molecular Pharmacology 96 (4), 485-492, 2019
462019
Tracking S4 movement by gating pore currents in the bacterial sodium channel NaChBac
TM Gamal El-Din, T Scheuer, WA Catterall
The Journal of general physiology 144 (2), 147-157, 2014
302014
Molecular dissection of multiphase inactivation of the bacterial sodium channel NaVAb
TM Gamal El-Din, MJ Lenaeus, K Ramanadane, N Zheng, WA Catterall
The Journal of General Physiology, jgp. 201711884, 2018
222018
Autism-associated mutations in KV7 channels induce gating pore current
TM Gamal El-Din, T Lantin, CW Tschumi, B Juarez, M Quinlan, ...
Proceedings of the National Academy of Sciences 118 (45), 2021
172021
Druggability of Voltage-gated Sodium Channels–Exploring Old and New Drug Receptor Sites
G Wisedchaisri, TM Gamal El-Din
Frontiers in Pharmacology, 903, 2022
152022
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Articles 1–20