Integrating carbon–halogen bond formation into medicinal plant metabolism W Runguphan, X Qu, SE O’Connor Nature 468 (7322), 461-464, 2010 | 234 | 2010 |
Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis XY Jia, ZH Tian, L Shao, XD Qu, QF Zhao, J Tang, GL Tang, W Liu Chemistry & biology 13 (6), 575-585, 2006 | 194 | 2006 |
Insights into Pyrroindomycin Biosynthesis Reveal a Uniform Paradigm for Tetramate/Tetronate Formation Q Wu, Z Wu, X Qu, W Liu Journal of the American Chemical Society, 2012 | 67 | 2012 |
Cloning and characterization of a bacterial iterative type I polyketide synthase gene encoding the 6-methylsalicyclic acid synthase L Shao, XD Qu, XY Jia, QF Zhao, ZH Tian, M Wang, GL Tang, W Liu Biochemical and biophysical research communications 345 (1), 133-139, 2006 | 67 | 2006 |
Enantioselective synthesis of 1-aryl-substituted tetrahydroisoquinolines employing imine reductase J Zhu, H Tan, L Yang, Z Dai, L Zhu, H Ma, Z Deng, Z Tian, X Qu ACS Catalysis 7 (10), 7003-7007, 2017 | 65 | 2017 |
Biosynthetic Pathway for High Structural Diversity of a Common Dilactone Core in Antimycin Production Y Yan, L Zhang, T Ito, X Qu, Y Asakawa, T Awakawa, I Abe, W Liu Organic Letters 14, 4142, 2012 | 65 | 2012 |
Efficient biosynthesis of heterodimeric C3-aryl pyrroloindoline alkaloids W Tian, C Sun, M Zheng, JR Harmer, M Yu, Y Zhang, H Peng, D Zhu, ... Nature Communications 9 (1), 4428, 2018 | 59 | 2018 |
ThioFinder: A Web-Based Tool for the Identification of Thiopeptide Gene Clusters in DNA Sequences J Li, X Qu, X He, L Duan, G Wu, D Bi, Z Deng, W Liu, HY Ou PLOS ONE 7 (9), e45878, 2012 | 59 | 2012 |
Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor X Qu, N Jiang, F Xu, L Shao, G Tang, B Wilkinson, W Liu Molecular BioSystems 7 (3), 852-861, 2011 | 59 | 2011 |
Activation of Natural Products Biosynthetic Pathways via a Protein Modification Level Regulation B Zhang, W Tian, S Wang, X Yan, X Jia, GK Pierens, W Chen, H Ma, ... ACS Chemical Biology 12 (7), 1732-1736, 2017 | 52 | 2017 |
Uncovering the Formation and Selection of Benzylmalonyl-CoA from the Biosynthesis of Splenocin and Enterocin Reveals a Versatile Way to Introduce Amino Acids into Polyketide … C Chang, R Huang, Y Yan, Z Ma, Hongmin, Dai, B Zhang, Z Deng, W Liu, ... Journal of the American Chemical Socity 137 (12), 4183–4190, 2015 | 51 | 2015 |
Deciphering piperidine formation in polyketide-derived indolizidines reveals a thioester reduction, transamination, and unusual imine reduction process H Peng, E Wei, J Wang, Y Zhang, L Cheng, H Ma, Z Deng, X Qu ACS Chemical Biology 11 (12), 3278-3283, 2016 | 50 | 2016 |
A dual role reductase from phytosterols catabolism enables the efficient production of valuable steroid precursors H Peng, Y Wang, K Jiang, X Chen, W Zhang, Y Zhang, Z Deng, X Qu Angewandte Chemie International Edition 60 (10), 5414-5420, 2020 | 43 | 2020 |
Caerulomycins and collismycins share a common paradigm for 2, 2′-bipyridine biosynthesis via an unusual hybrid polyketide–peptide assembly logic X Qu, B Pang, Z Zhang, M Chen, Z Wu, Q Zhao, Q Zhang, Y Wang, Y Liu, ... Journal of the American Chemical Society 134 (22), 9038-9041, 2012 | 42 | 2012 |
A biocatalytic hydroxylation-enabled unified approach to C19-hydroxylated steroids J Wang, Y Zhang, H Liu, Y Shang, L Zhou, P Wei, WB Yin, Z Deng, X Qu, ... Nature communications 10 (1), 3378, 2019 | 41 | 2019 |
Biosynthesis of plant tetrahydroisoquinoline alkaloids through an imine reductase route L Yang, J Zhu, C Sun, Z Deng, X Qu Chemical science 11 (2), 364-371, 2020 | 39 | 2020 |
Efficient editing DNA regions with high sequence identity in actinomycetal genomes by a CRISPR-Cas9 system J Mo, S Wang, W Zhang, C Li, Z Deng, L Zhang, X Qu Synthetic and systems biotechnology 4 (2), 86-91, 2019 | 39 | 2019 |
Structural basis of a broadly selective acyltransferase from the polyketide synthase of splenocin Y Li, W Zhang, H Zhang, W Tian, L Wu, S Wang, M Zheng, J Zhang, C Sun, ... Angewandte Chemie 130 (20), 5925-5929, 2018 | 38 | 2018 |
Transcriptome Mining of Active Biosynthetic Pathways and Their Associated Products in Streptomyces flaveolus X Qu, C Lei, W Liu Angewandte Chemie International Edition 50 (41), 9651-9654, 2011 | 38 | 2011 |
Deciphering carbamoylpolyoxamic acid biosynthesis reveals unusual acetylation cycle associated with tandem reduction and sequential hydroxylation J Qi, D Wan, H Ma, Y Liu, R Gong, X Qu, Y Sun, Z Deng, W Chen Cell Chemical Biology 23 (8), 935-944, 2016 | 31 | 2016 |