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Donald Backos
Donald Backos
A.R. Fellow, Computational Chemistry at Pfizer (Boulder, CO)
Verified email at pfizer.com - Homepage
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Cited by
Year
Lysine glutarylation is a protein posttranslational modification regulated by SIRT5
M Tan, C Peng, KA Anderson, P Chhoy, Z Xie, L Dai, J Park, Y Chen, ...
Cell metabolism 19 (4), 605-617, 2014
7512014
Complement proteins bind to nanoparticle protein corona and undergo dynamic exchange in vivo
F Chen, G Wang, JI Griffin, B Brenneman, NK Banda, VM Holers, ...
Nature nanotechnology 12 (4), 387-393, 2017
4882017
Structure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligase
CC Franklin, DS Backos, I Mohar, CC White, HJ Forman, TJ Kavanagh
Molecular aspects of medicine 30 (1-2), 86-98, 2009
4492009
Strategies and approaches of targeting STAT3 for cancer treatment
SL Furtek, DS Backos, CJ Matheson, P Reigan
ACS chemical biology 11 (2), 308-318, 2016
3662016
Targeting WEE1 kinase in cancer
CJ Matheson, DS Backos, P Reigan
Trends in pharmacological sciences 37 (10), 872-881, 2016
3622016
Motor protein–dependent transport of AMPA receptors into spines during long-term potentiation
SS Correia, S Bassani, TC Brown, MF Lisé, DS Backos, A El-Husseini, ...
Nature neuroscience 11 (4), 457-466, 2008
3052008
SIRT4 is a lysine deacylase that controls leucine metabolism and insulin secretion
KA Anderson, FK Huynh, K Fisher-Wellman, JD Stuart, BS Peterson, ...
Cell metabolism 25 (4), 838-855. e15, 2017
2912017
Brain-derived neurotrophic factor regulates the Expression and synaptic delivery ofα-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor subunits in hippocampal neurons
MV Caldeira, CV Melo, DB Pereira, R Carvalho, SS Correia, DS Backos, ...
Journal of Biological Chemistry 282 (17), 12619-12628, 2007
2882007
NMDA receptor-dependent activation of the small GTPase Rab5 drives the removal of synaptic AMPA receptors during hippocampal LTD
TC Brown, IC Tran, DS Backos, JA Esteban
Neuron 45 (1), 81-94, 2005
2842005
A class of reactive acyl-CoA species reveals the non-enzymatic origins of protein acylation
GR Wagner, DP Bhatt, TM O’Connell, JW Thompson, LG Dubois, ...
Cell metabolism 25 (4), 823-837. e8, 2017
2332017
The role of glutathione in brain tumor drug resistance
DS Backos, CC Franklin, P Reigan
Biochemical pharmacology 83 (8), 1005-1012, 2012
2172012
Dual role of the exocyst in AMPA receptor targeting and insertion into the postsynaptic membrane
NZ Gerges, DS Backos, CN Rupasinghe, MR Spaller, JA Esteban
The EMBO journal 25 (8), 1623-1634, 2006
1802006
Local control of AMPA receptor trafficking at the postsynaptic terminal by a small GTPase of the Rab family
NZ Gerges, DS Backos, JA Esteban
Journal of Biological Chemistry 279 (42), 43870-43878, 2004
1802004
Oxidative stress and the ER stress response in a murine model for early-stage alcoholic liver disease
JJ Galligan, RL Smathers, CT Shearn, KS Fritz, DS Backos, H Jiang, ...
Journal of toxicology 2012, 2012
1132012
Diindolylmethane analogs bind NR4A1 and are NR4A1 antagonists in colon cancer cells
SO Lee, X Li, E Hedrick, UH Jin, RB Tjalkens, DS Backos, L Li, Y Zhang, ...
Molecular endocrinology 28 (10), 1729-1739, 2014
1102014
Independent functions of hsp90 in neurotransmitter release and in the continuous synaptic cycling of AMPA receptors
NZ Gerges, IC Tran, DS Backos, JM Harrell, M Chinkers, WB Pratt, ...
Journal of Neuroscience 24 (20), 4758-4766, 2004
1092004
Post-translational oxidative modification and inactivation of mitochondrial complex I in epileptogenesis
K Ryan, DS Backos, P Reigan, M Patel
Journal of Neuroscience 32 (33), 11250-11258, 2012
1012012
Investigating the sensitivity of NAD+-dependent sirtuin deacylation activities to NADH
AS Madsen, C Andersen, M Daoud, KA Anderson, JS Laursen, ...
Journal of Biological Chemistry 291 (13), 7128-7141, 2016
1002016
Posttranslational modification and regulation of glutamate–cysteine ligase by the α, β-unsaturated aldehyde 4-hydroxy-2-nonenal
DS Backos, KS Fritz, JR Roede, DR Petersen, CC Franklin
Free Radical Biology and Medicine 50 (1), 14-26, 2011
812011
Increased carbonylation of the lipid phosphatase PTEN contributes to Akt2 activation in a murine model of early alcohol-induced steatosis
CT Shearn, RL Smathers, DS Backos, P Reigan, DJ Orlicky, DR Petersen
Free Radical Biology and Medicine 65, 680-692, 2013
772013
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