| Synthesis and structure–activity relationships of novel 1-arylmethyl-3-aryl-1H-pyrazole-5-carbohydrazide hydrazone derivatives as potential agents against A549 lung cancer cells Y Xia, CD Fan, BX Zhao, J Zhao, DS Shin, JY Miao European journal of medicinal chemistry 43 (11), 2347-2353, 2008 | 262 | 2008 |
| Chloroquine inhibits cell growth and induces cell death in A549 lung cancer cells C Fan, W Wang, B Zhao, S Zhang, J Miao Bioorganic & medicinal chemistry 14 (9), 3218-3222, 2006 | 221 | 2006 |
| A novel copper complex of salicylaldehyde pyrazole hydrazone induces apoptosis through up-regulating integrin β4 in H322 lung carcinoma cells CD Fan, H Su, J Zhao, BX Zhao, SL Zhang, JY Miao European journal of medicinal chemistry 45 (4), 1438-1446, 2010 | 123 | 2010 |
| Ubiquitin-dependent regulation of phospho-AKT dynamics by the ubiquitin E3 ligase, NEDD4-1, in the IGF-1 response CD Fan, MA Lum, C Xu, JD Black, X Wang Journal of Biological Chemistry, 2012 | 122 | 2012 |
| Regulation of Mdm2 protein stability and the p53 response by NEDD4-1 E3 ligase C Xu, CD Fan, X Wang Oncogene 34 (3), 281-289, 2015 | 88 | 2015 |
| FL118 induces p53-dependent senescence in colorectal cancer cells by promoting degradation of MdmX X Ling, C Xu, C Fan, K Zhong, F Li, X Wang Cancer research 74 (24), 7487-7497, 2014 | 65 | 2014 |
| Synthesis and preliminary biological evaluation of novel pyrazolo [1, 5-a] pyrazin-4 (5H)-one derivatives as potential agents against A549 lung cancer cells JH Zhang, CD Fan, BX Zhao, DS Shin, WL Dong, YS Xie, JY Miao Bioorganic & medicinal chemistry 16 (24), 10165-10171, 2008 | 65 | 2008 |
| Synthesis and discovery of autophagy inducers for A549 and H460 lung cancer cells, novel 1-(2′-hydroxy-3′-aroxypropyl)-3-aryl-1H-pyrazole-5-carbohydrazide derivatives CD Fan, BX Zhao, F Wei, GH Zhang, WL Dong, JY Miao Bioorganic & medicinal chemistry letters 18 (14), 3860-3864, 2008 | 49 | 2008 |
| Homo-trimerization is essential for the transcription factor function of Myrf for oligodendrocyte differentiation D Kim, J Choi, C Fan, RS Shearer, M Sharif, P Busch, Y Park Nucleic acids research 45 (9), 5112-5125, 2017 | 42 | 2017 |
| An ABCG2 non-substrate anticancer agent FL118 targets drug-resistant cancer stem-like cells and overcomes treatment resistance of human pancreatic cancer X Ling, W Wu, C Fan, C Xu, J Liao, LJ Rich, RY Huang, EA Repasky, ... Journal of Experimental & Clinical Cancer Research 37, 1-19, 2018 | 38 | 2018 |
| Novel complex of copper and a salicylaldehyde pyrazole hydrazone derivative induces apoptosis through up-regulating integrin β4 in vascular endothelial cells C Fan, J Zhao, B Zhao, S Zhang, J Miao Chemical research in toxicology 22 (9), 1517-1525, 2009 | 36 | 2009 |
| Targeting RING domains of Mdm2–MdmX E3 complex activates apoptotic arm of the p53 pathway in leukemia/lymphoma cells W Wu, C Xu, X Ling, C Fan, BP Buckley, MV Chernov, L Ellis, F Li, ... Cell death & disease 6 (12), e2035, 2015 | 28 | 2015 |
| A principled strategy for mapping enhancers to genes D Kim, H An, RS Shearer, M Sharif, C Fan, J Choi, S Ryu, Y Park Scientific reports 9 (1), 11043, 2019 | 21 | 2019 |
| Identifying oligodendrocyte enhancers governing Plp1 expression D Kim, H An, C Fan, Y Park Human molecular genetics 30 (23), 2225-2239, 2021 | 16 | 2021 |
| Functional mechanism and pathogenic potential of MYRF ICA domain mutations implicated in birth defects H An, C Fan, M Sharif, D Kim, Y Poitelon, Y Park Scientific reports 10 (1), 814, 2020 | 13 | 2020 |
| Synthesis and Primary Evaluation of Lung Cancer Cell Growth In-hibitory Activity of Novel 3-Arylmethyl-5-aroxymethylbutyrolactones L SHA, BX ZHAO, CD FAN, WLI TAN, JY MIAO Chinese Journal of Organic Chemistry 26 (04), 537, 2006 | 13 | 2006 |
| Elucidating the transactivation domain of the pleiotropic transcription factor Myrf J Choi, C Fan, D Kim, M Sharif, H An, Y Park Scientific reports 8 (1), 13075, 2018 | 12 | 2018 |
| Functional mechanisms of MYRF DNA-binding domain mutations implicated in birth defects C Fan, H An, M Sharif, D Kim, Y Park Journal of Biological Chemistry 296, 2021 | 9 | 2021 |
| Mdm2 Splice isoforms regulate the p53/Mdm2/Mdm4 regulatory circuit via RING domain-mediated ubiquitination of p53 and Mdm4 C Fan, X Wang Cell Cycle 16 (7), 660-664, 2017 | 9 | 2017 |
| The Thoc1 encoded ribonucleoprotein is a substrate for the NEDD4-1 E3 ubiquitin protein ligase F Song, C Fan, X Wang, DW Goodrich PloS one 8 (2), e57995, 2013 | 5 | 2013 |
Chao XuRoswell Park Cancer InstituteVerified email at roswellpark.org
