EGF receptor is required for KRAS-induced pancreatic tumorigenesis CM Ardito, BM Grüner, KK Takeuchi, C Lubeseder-Martellato, ... Cancer cell 22 (3), 304-317, 2012 | 537 | 2012 |
Rapid and tunable method to temporally control gene editing based on conditional Cas9 stabilization S Senturk, NH Shirole, DG Nowak, V Corbo, D Pal, A Vaughan, ... Nature Communications 8 (1), 14370, 2017 | 158 | 2017 |
PI3K regulation of RAC1 is required for KRAS-induced pancreatic tumorigenesis in mice CYC Wu, ES Carpenter, KK Takeuchi, CJ Halbrook, LV Peverley, H Bien, ... Gastroenterology 147 (6), 1405-1416. e7, 2014 | 123 | 2014 |
Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers T Ito, MJ Young, R Li, S Jain, A Wernitznig, JM Krill-Burger, CT Lemke, ... Nature genetics 53 (12), 1664-1672, 2021 | 79 | 2021 |
TP53 exon-6 truncating mutations produce separation of function isoforms with pro-tumorigenic functions NH Shirole, D Pal, ER Kastenhuber, S Senturk, J Boroda, P Pisterzi, ... Elife 5, e17929, 2016 | 79* | 2016 |
Molecular basis for substrate recruitment to the PRMT5 methylosome KM Mulvaney, C Blomquist, N Acharya, R Li, MJ Ranaghan, M O’Keefe, ... Molecular cell 81 (17), 3481-3495. e7, 2021 | 47 | 2021 |
GEMINI: a variational Bayesian approach to identify genetic interactions from combinatorial CRISPR screens M Zamanighomi, SS Jain, T Ito, D Pal, TP Daley, WR Sellers Genome biology 20, 1-10, 2019 | 40 | 2019 |
TGF-β reduces DNA ds-break repair mechanisms to heighten genetic diversity and adaptability of CD44+/CD24− cancer cells D Pal, A Pertot, NH Shirole, Z Yao, N Anaparthy, T Garvin, H Cox, ... Elife 6, e21615, 2017 | 40 | 2017 |
Investigation of the reciprocal relationship between the expression of two gap junction connexin proteins, connexin46 and connexin43 D Banerjee, S Das, SA Molina, D Madgwick, MR Katz, S Jena, ... Journal of biological chemistry 286 (27), 24519-24533, 2011 | 40 | 2011 |
The evolution of TP53 mutations: from loss-of-function to separation-of-function mutants M Miller, N Shirole, R Tian, D Pal, R Sordella Journal of cancer biology & research 4 (4), 2016 | 33 | 2016 |
Direct interaction between a precursor mature domain and transport component Tha4 during twin arginine transport of chloroplasts D Pal, K Fite, C Dabney-Smith Plant physiology 161 (2), 990-1001, 2013 | 30 | 2013 |
Role of a novel coiled-coil domain-containing protein CCDC69 in regulating central spindle assembly D Pal, D Wu, A Haruta, F Matsumura, Q Wei Cell cycle 9 (20), 4117-4129, 2010 | 27 | 2010 |
Targeted Covalent Inhibition of Plasmodium FK506 Binding Protein 35 TC Atack, DD Raymond, CA Blomquist, CF Pasaje, PR McCarren, ... ACS Medicinal Chemistry Letters 11 (11), 2131-2138, 2020 | 11 | 2020 |
An epigenetic switch regulates the ontogeny of AXL-positive/EGFR-TKi-resistant cells by modulating miR-335 expression P Safaric Tepes, D Pal, T Lindsted, I Ibarra, A Lujambio, ... Elife 10, e66109, 2021 | 8 | 2021 |
Understanding genetic and epigenetic mechanisms of genomic instability, phenotypic diversity and resistance in cancer D Pal State University of New York at Stony Brook, 2017 | | 2017 |
Coiled-coil domain-containing protein 69 (CCDC69) acts as a scaffold and a microtubule-destabilizing factor to regulate central spindle assembly D Pal Kansas State University, 2010 | | 2010 |