Ezetimibe in Combination With Simvastatin Reduces Remnant Cholesterol Without Affecting Biliary Lipid Concentrations in Gallstone Patients O Ahmed, K Littmann, U Gustafsson, C Pramfalk, K Öörni, L Larsson, ... Journal of the American Heart Association 7 (24), e009876, 2018 | 37 | 2018 |
Insights from liver‐humanized mice on cholesterol lipoprotein metabolism and LXR‐agonist pharmacodynamics in humans ME Minniti, M Pedrelli, LL Vedin, AS Delbès, RGP Denis, K Öörni, C Sala, ... Hepatology, 2019 | 29 | 2019 |
Enzymatic Quantification of Liver Lipids After Folch Extraction ME Minniti, O Ahmed, M Pedrelli Kupffer Cells, 101-108, 2020 | 10 | 2020 |
Soat2 ties cholesterol metabolism to β‐oxidation and glucose tolerance in male mice C Pramfalk, O Ahmed, M Pedrelli, ME Minniti, S Luquet, RGP Denis, ... Journal of Internal Medicine 292 (2), 296-307, 2022 | 7 | 2022 |
Generation of new hepatocyte-like in vitro models better resembling human lipid metabolism C Pramfalk, T Jakobsson, CRC Verzijl, ME Minniti, C Obensa, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2020 | 4 | 2020 |
Liver-humanized mice exhibit lipoprotein-specific phenotypes when grafted with human hepatocytes from different donors ME Minniti, LL Vedin, EM Wilson, KR Steffensen, P Parini Atherosclerosis 263, e7, 2017 | 3 | 2017 |
Hepatic transcriptional effects of simvastatin and the possible impact on COVID-19 O Ahmed, AK Mukarram, C Pirazzini, EE Marasco, M Pedrelli, ME Minniti, ... Atherosclerosis 331, e143-e144, 2021 | 1 | 2021 |
Mice with humanized livers reveal the involvement of hepatocyte circadian clocks in rhythmic behavior and physiology AS Delbes, M Quinones, C Gobet, J Castel, RGP Denis, B Jeremy, ... bioRxiv, 2022.09. 08.506890, 2022 | | 2022 |
Liver-Humanized Mice Provide a New Platform to Study Human Cardiometabolic Diseases ME Minniti, L Foquet, M Pedrelli, E Gierer, D Goldman, R Copenhaver, ... Circulation 144 (Suppl_1), A10979-A10979, 2021 | | 2021 |
Liver-humanized mice fed a NASH-diet are an advanced model to study cardiometabolic diseases ME Minniti, L Foquet, E Gierer, M Pedrelli, D Goldman, R Copenhaver, ... Atherosclerosis 331, e143, 2021 | | 2021 |
Metabolic characterization of the high-fat/high sucrose diet challenge in liver-humanized mice ME Minniti, M Pedrelli, LL Vedin, AS Delbès, RGP Denis, P Garagnani, ... Atherosclerosis 315, e99-e100, 2020 | | 2020 |
Fighting Cardiometabolic Disease: Validation of New Experimental Models and Therapeutic Targets ME Minniti PQDT-Global, 2020 | | 2020 |
Reduction Of Bile Acid Synthesis And Intrahepatic Lipid Accumulation In Liver-Humanized Mice Define The Unfavorable Pharmacodynamics Of Lxr Agonism In Humans ME Minniti, LL Vedin, M Pedrelli, K Öörni, SH Luquet, EM Wilson, J Bial, ... Atherosclerosis 287, e28-e29, 2019 | | 2019 |
Why are humans LDL-animals and mice are not? Hepatic APOB mRNA editing and plasma PLTP activity are the cause, not CETP ME Minniti, M Pedrelli, LL Vedin, AS Delbes, K Öörni, EM Wilson, ... Atherosclerosis 275, e33, 2018 | | 2018 |
Increased lipoprotein binding to arterial proteoglycans and normal macrophage cholesterol efflux capacity define the pro-atherogenic feature of CKD dyslipidemia M Pedrelli, P Stenvinkel, ME Minniti, K Emma, A Dikkers, S Ebtehaj, ... Atherosclerosis 252, e237, 2016 | | 2016 |