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Jun Ishihara
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Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing
J Ishihara, A Ishihara, K Fukunaga, K Sasaki, MJV White, PS Briquez, ...
Nature communications 9 (1), 2163, 2018
1882018
Collagen-binding IL-12 enhances tumour inflammation and drives the complete remission of established immunologically cold mouse tumours
A Mansurov, J Ishihara, P Hosseinchi, L Potin, TM Marchell, A Ishihara, ...
Nature biomedical engineering 4 (5), 531-543, 2020
1562020
Matrix-binding checkpoint immunotherapies enhance antitumor efficacy and reduce adverse events
J Ishihara, K Fukunaga, A Ishihara, HM Larsson, L Potin, P Hosseinchi, ...
Science translational medicine 9 (415), eaan0401, 2017
1562017
Targeted antibody and cytokine cancer immunotherapies through collagen affinity
J Ishihara, A Ishihara, K Sasaki, SSY Lee, JM Williford, M Yasui, H Abe, ...
Science translational medicine 11 (487), eaau3259, 2019
1532019
Recruitment of CD103+ dendritic cells via tumor-targeted chemokine delivery enhances efficacy of checkpoint inhibitor immunotherapy
JAH John-Michael Williford, Jun Ishihara, Ako Ishihara, Aslan Mansurov ...
Science Advances 5 (12), eaay1357, 2019
1062019
The heparin binding domain of von Willebrand factor binds to growth factors and promotes angiogenesis in wound healing
J Ishihara, A Ishihara, RD Starke, CR Peghaire, KE Smith, TAJ McKinnon, ...
Blood, The Journal of the American Society of Hematology 133 (24), 2559-2569, 2019
1002019
Integrin-αvβ3 regulates thrombopoietin-mediated maintenance of hematopoietic stem cells
T Umemoto, M Yamato, J Ishihara, Y Shiratsuchi, M Utsumi, Y Morita, ...
Blood, The Journal of the American Society of Hematology 119 (1), 83-94, 2012
902012
Engineered collagen-binding serum albumin as a drug conjugate carrier for cancer therapy
K Sasaki, J Ishihara, A Ishihara, R Miura, A Mansurov, K Fukunaga, ...
Science advances 5 (8), eaaw6081, 2019
742019
Targeting inflammatory sites through collagen affinity enhances the therapeutic efficacy of anti-inflammatory antibodies
K Katsumata, J Ishihara, A Mansurov, A Ishihara, MM Raczy, E Yuba, ...
Science advances 5 (11), eaay1971, 2019
552019
Masking the immunotoxicity of interleukin-12 by fusing it with a domain of its receptor via a tumour-protease-cleavable linker
A Mansurov, P Hosseinchi, K Chang, AL Lauterbach, LT Gray, AT Alpar, ...
Nature Biomedical Engineering 6 (7), 819-829, 2022
412022
Improving efficacy and safety of agonistic anti-CD40 antibody through extracellular matrix affinity
J Ishihara, A Ishihara, L Potin, P Hosseinchi, K Fukunaga, M Damo, ...
Molecular cancer therapeutics 17 (11), 2399-2411, 2018
402018
Lymphangiogenesis-inducing vaccines elicit potent and long-lasting T cell immunity against melanomas
MS Sasso, N Mitrousis, Y Wang, PS Briquez, S Hauert, J Ishihara, ...
Science Advances 7 (13), eabe4362, 2021
392021
Prolonged residence of an albumin–IL-4 fusion protein in secondary lymphoid organs ameliorates experimental autoimmune encephalomyelitis
A Ishihara, J Ishihara, EA Watkins, AC Tremain, M Nguyen, A Solanki, ...
Nature Biomedical Engineering 5 (5), 387-398, 2021
292021
Nov/CCN3 regulates long-term repopulating activity of murine hematopoietic stem cells via integrin αvβ3
J Ishihara, T Umemoto, M Yamato, Y Shiratsuchi, S Takaki, BG Petrich, ...
International journal of hematology 99, 393-406, 2014
292014
Immunoengineering approaches for cytokine therapy
A Mansurov, A Lauterbach, E Budina, AT Alpar, JA Hubbell, J Ishihara
American Journal of Physiology-Cell Physiology 321 (2), C369-C383, 2021
212021
A role for c-Kit in the maintenance of undifferentiated human mesenchymal stromal cells
S Suphanantachat, T Iwata, J Ishihara, M Yamato, T Okano, Y Izumi
Biomaterials 35 (11), 3618-3626, 2014
212014
Suppression of rheumatoid arthritis by enhanced lymph node trafficking of engineered interleukin‐10 in murine models
E Yuba, E Budina, K Katsumata, A Ishihara, A Mansurov, AT Alpar, ...
Arthritis & Rheumatology 73 (5), 769-778, 2021
202021
Targeting advanced prostate cancer with STEAP1 chimeric antigen receptor T cell and tumor-localized IL-12 immunotherapy
V Bhatia, NV Kamat, TE Pariva, LT Wu, A Tsao, K Sasaki, H Sun, G Javier, ...
Nature Communications 14 (1), 2041, 2023
192023
Requirement of integrin β3 for iron transportation during enamel formation
T Yoshida, Y Kumashiro, T Iwata, J Ishihara, T Umemoto, Y Shiratsuchi, ...
Journal of dental research 91 (12), 1154-1159, 2012
192012
Conferring extracellular matrix affinity enhances local therapeutic efficacy of anti-TNF-α antibody in a murine model of rheumatoid arthritis
JH Kiyomitsu Katsumata, Jun Ishihara, Kazuto Fukunaga, Ako Ishihara, Eiji ...
Arthritis Res Ther 21 (298), 2019
162019
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