Synthetic biological circuits within an orthogonal central dogma A Costello, AH Badran Trends in biotechnology 39 (1), 59-71, 2021 | 51 | 2021 |
Leaky expression of the TET‐On system hinders control of endogenous miRNA abundance A Costello, NT Lao, C Gallagher, B Capella Roca, LAN Julius, S Suda, ... Biotechnology journal 14 (3), 1800219, 2019 | 34 | 2019 |
Continuous translation of circularized mRNA improves recombinant protein titer A Costello, NT Lao, N Barron, M Clynes Metabolic engineering 52, 284-292, 2019 | 33 | 2019 |
Reinventing the wheel: synthetic circular RNAs for mammalian cell engineering A Costello, NT Lao, N Barron, M Clynes Trends in biotechnology 38 (2), 217-230, 2020 | 30 | 2020 |
Ultra-deep next generation mitochondrial genome sequencing reveals widespread heteroplasmy in Chinese hamster ovary cells PS Kelly, C Clarke, A Costello, C Monger, J Meiller, H Dhiman, N Borth, ... Metabolic engineering 41, 11-22, 2017 | 23 | 2017 |
Depletion of endogenous miRNA-378-3p increases peak cell density of CHO DP12 cells and is correlated with elevated levels of ubiquitin carboxyl-terminal hydrolase 14 A Costello, O Coleman, NT Lao, M Henry, P Meleady, N Barron, M Clynes Journal of biotechnology 288, 30-40, 2018 | 15 | 2018 |
Directed evolution of rRNA improves translation kinetics and recombinant protein yield F Liu, S Bratulić, A Costello, TP Miettinen, AH Badran Nature Communications 12 (1), 5638, 2021 | 12 | 2021 |
Improved yield of rhEPO in CHO cells with synthetic 5′ UTR A Costello, NT Lao, N Barron, M Clynes Biotechnology letters 41, 231-239, 2019 | 9 | 2019 |
Conditional Knockdown of Endogenous MicroRNAs in CHO Cells Using TET-ON-SanDI Sponge Vectors A Costello, N Lao, M Clynes, N Barron Heterologous Protein Production in CHO Cells: Methods and Protocols, 87-100, 2017 | 9 | 2017 |
Subphysiological temperature induces pervasive alternative splicing in Chinese hamster ovary cells I Tzani, C Monger, K Motheramgari, C Gallagher, R Hagan, P Kelly, ... Biotechnology and Bioengineering 117 (8), 2489-2503, 2020 | 7 | 2020 |
Development of whole-cell and cell-free biosensors for the detection and differentiation of organic and inorganic forms of copper A Costello, J Parker, M Clynes, R Murphy Metallomics 12 (11), 1729-1734, 2020 | 5 | 2020 |
A proteomic profiling dataset of recombinant Chinese hamster ovary cells showing enhanced cellular growth following miR-378 depletion O Coleman, A Costello, M Henry, NT Lao, N Barron, M Clynes, P Meleady Data in brief 21, 2679-2688, 2018 | 5 | 2018 |
RNA manipulations to improve recombinant protein production in Chinese hamster ovary cells A Costello Dublin City University, 2019 | | 2019 |
5 Chapter Five: Depletion of endogenous miRNA-378-3p increases peak cell density of CHO DP12 cells and is correlated with elevated levels of ubiquitin carboxyl-terminal … O Coleman, A Costello, NT Lao, M Henry, P Meleady, N Barron, M Clynes This thesis is dedicated to my loving family, 159, 2019 | | 2019 |
Rolling cycle translation of circularized infinite open reading frames; fooling the ribosome A Costello, M Clynes, N Lao, N Barron | | 2018 |