Follow
Alan Costello
Alan Costello
Verified email at scripps.edu
Title
Cited by
Cited by
Year
Synthetic biological circuits within an orthogonal central dogma
A Costello, AH Badran
Trends in biotechnology 39 (1), 59-71, 2021
512021
Leaky expression of the TET‐On system hinders control of endogenous miRNA abundance
A Costello, NT Lao, C Gallagher, B Capella Roca, LAN Julius, S Suda, ...
Biotechnology journal 14 (3), 1800219, 2019
342019
Continuous translation of circularized mRNA improves recombinant protein titer
A Costello, NT Lao, N Barron, M Clynes
Metabolic engineering 52, 284-292, 2019
332019
Reinventing the wheel: synthetic circular RNAs for mammalian cell engineering
A Costello, NT Lao, N Barron, M Clynes
Trends in biotechnology 38 (2), 217-230, 2020
302020
Ultra-deep next generation mitochondrial genome sequencing reveals widespread heteroplasmy in Chinese hamster ovary cells
PS Kelly, C Clarke, A Costello, C Monger, J Meiller, H Dhiman, N Borth, ...
Metabolic engineering 41, 11-22, 2017
232017
Depletion of endogenous miRNA-378-3p increases peak cell density of CHO DP12 cells and is correlated with elevated levels of ubiquitin carboxyl-terminal hydrolase 14
A Costello, O Coleman, NT Lao, M Henry, P Meleady, N Barron, M Clynes
Journal of biotechnology 288, 30-40, 2018
152018
Directed evolution of rRNA improves translation kinetics and recombinant protein yield
F Liu, S Bratulić, A Costello, TP Miettinen, AH Badran
Nature Communications 12 (1), 5638, 2021
122021
Improved yield of rhEPO in CHO cells with synthetic 5′ UTR
A Costello, NT Lao, N Barron, M Clynes
Biotechnology letters 41, 231-239, 2019
92019
Conditional Knockdown of Endogenous MicroRNAs in CHO Cells Using TET-ON-SanDI Sponge Vectors
A Costello, N Lao, M Clynes, N Barron
Heterologous Protein Production in CHO Cells: Methods and Protocols, 87-100, 2017
92017
Subphysiological temperature induces pervasive alternative splicing in Chinese hamster ovary cells
I Tzani, C Monger, K Motheramgari, C Gallagher, R Hagan, P Kelly, ...
Biotechnology and Bioengineering 117 (8), 2489-2503, 2020
72020
Development of whole-cell and cell-free biosensors for the detection and differentiation of organic and inorganic forms of copper
A Costello, J Parker, M Clynes, R Murphy
Metallomics 12 (11), 1729-1734, 2020
52020
A proteomic profiling dataset of recombinant Chinese hamster ovary cells showing enhanced cellular growth following miR-378 depletion
O Coleman, A Costello, M Henry, NT Lao, N Barron, M Clynes, P Meleady
Data in brief 21, 2679-2688, 2018
52018
RNA manipulations to improve recombinant protein production in Chinese hamster ovary cells
A Costello
Dublin City University, 2019
2019
5 Chapter Five: Depletion of endogenous miRNA-378-3p increases peak cell density of CHO DP12 cells and is correlated with elevated levels of ubiquitin carboxyl-terminal …
O Coleman, A Costello, NT Lao, M Henry, P Meleady, N Barron, M Clynes
This thesis is dedicated to my loving family, 159, 2019
2019
Rolling cycle translation of circularized infinite open reading frames; fooling the ribosome
A Costello, M Clynes, N Lao, N Barron
2018
The system can't perform the operation now. Try again later.
Articles 1–15