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Erik Sontheimer
Erik Sontheimer
RNA Therapeutics Institute, UMass Medical School
Verified email at umassmed.edu
Title
Cited by
Cited by
Year
Origins and mechanisms of miRNAs and siRNAs
RW Carthew, EJ Sontheimer
Cell 136 (4), 642-655, 2009
60692009
CRISPR interference limits horizontal gene transfer in staphylococci by targeting DNA
LA Marraffini, EJ Sontheimer
science 322 (5909), 1843-1845, 2008
21212008
Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways
YS Lee, K Nakahara, JW Pham, K Kim, Z He, EJ Sontheimer, RW Carthew
Cell 117 (1), 69-81, 2004
17092004
CRISPR interference: RNA-directed adaptive immunity in bacteria and archaea
LA Marraffini, EJ Sontheimer
Nature Reviews Genetics 11 (3), 181-190, 2010
12872010
Self versus non-self discrimination during CRISPR RNA-directed immunity
LA Marraffini, EJ Sontheimer
Nature 463 (7280), 568-571, 2010
9352010
Efficient genome engineering in human pluripotent stem cells using Cas9 from Neisseria meningitidis
Z Hou, Y Zhang, NE Propson, SE Howden, LF Chu, EJ Sontheimer, ...
Proceedings of the National Academy of Sciences 110 (39), 15644-15649, 2013
9002013
Assembly and function of RNA silencing complexes
EJ Sontheimer
Nature Reviews Molecular Cell Biology 6 (2), 127-138, 2005
6102005
Target DNA interference with crRNA
EJ Sontheimer, LA Marraffini
US Patent App. 12/565,589, 2010
5822010
A Dicer-2-dependent 80s complex cleaves targeted mRNAs during RNAi in Drosophila
JW Pham, JL Pellino, YS Lee, RW Carthew, EJ Sontheimer
Cell 117 (1), 83-94, 2004
5822004
The U5 and U6 small nuclear RNAs as active site components of the spliceosome
EJ Sontheimer, JA Steitz
Science 262 (5142), 1989-1996, 1993
5311993
Naturally occurring off-switches for CRISPR-Cas9
A Pawluk, N Amrani, Y Zhang, B Garcia, Y Hidalgo-Reyes, J Lee, A Edraki, ...
Cell 167 (7), 1829-1838. e9, 2016
4192016
Site-specific cross-linking of mammalian U5 snRNP to the 5'splice site before the first step of pre-mRNA splicing.
JR Wyatt, EJ Sontheimer, JA Steitz
Genes & Development 6 (12b), 2542-2553, 1992
4111992
Silencing by small RNAs is linked to endosomal trafficking
YS Lee, S Pressman, AP Andress, K Kim, JL White, JJ Cassidy, X Li, ...
Nature cell biology 11 (9), 1150-1156, 2009
3862009
Processing-independent CRISPR RNAs limit natural transformation in Neisseria meningitidis
Y Zhang, N Heidrich, BJ Ampattu, CW Gunderson, HS Seifert, C Schoen, ...
Molecular cell 50 (4), 488-503, 2013
3812013
Silence from within: endogenous siRNAs and miRNAs
EJ Sontheimer, RW Carthew
Cell 122 (1), 9-12, 2005
3802005
Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses
D Wang, H Mou, S Li, Y Li, S Hough, K Tran, J Li, H Yin, DG Anderson, ...
Human gene therapy 26 (7), 432-442, 2015
3792015
A broad-spectrum inhibitor of CRISPR-Cas9
LB Harrington, KW Doxzen, E Ma, JJ Liu, GJ Knott, A Edraki, B Garcia, ...
Cell 170 (6), 1224-1233. e15, 2017
2712017
Metal ion catalysis during splicing of premessenger RNA
EJ Sontheimer, S Sun, JA Piccirilli
Nature 388 (6644), 801-805, 1997
2461997
A compact, high-accuracy Cas9 with a dinucleotide PAM for in vivo genome editing
A Edraki, A Mir, R Ibraheim, I Gainetdinov, Y Yoon, CQ Song, Y Cao, ...
Molecular cell 73 (4), 714-726. e4, 2019
2222019
Metal ion catalysis during the exon-ligation step of nuclear pre-mRNA splicing: extending the parallels between the spliceosome and group II introns.
PM Gordon, EJ Sontheimer, JA Piccirilli
Rna 6 (2), 199-205, 2000
1922000
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