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Yan Xu
Yan Xu
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Year
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes
W Sungnak, N Huang, C Bécavin, M Berg, R Queen, M Litvinukova, ...
Nature medicine 26 (5), 681-687, 2020
27082020
SARS-CoV-2 receptor ACE2 is an interferon-stimulated gene in human airway epithelial cells and is detected in specific cell subsets across tissues
CGK Ziegler, SJ Allon, SK Nyquist, IM Mbano, VN Miao, CN Tzouanas, ...
Cell 181 (5), 1016-1035. e19, 2020
23422020
Single-cell RNA sequencing identifies diverse roles of epithelial cells in idiopathic pulmonary fibrosis
Y Xu, T Mizuno, A Sridharan, Y Du, M Guo, J Tang, ...
JCI insight 1 (20), 2016
5072016
SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production
G Chen, TR Korfhagen, Y Xu, J Kitzmiller, SE Wert, Y Maeda, A Gregorieff, ...
The Journal of clinical investigation 119 (10), 2914-2924, 2009
4292009
Defective lipoxin-mediated anti-inflammatory activity in the cystic fibrosis airway
CL Karp, LM Flick, KW Park, S Softic, TM Greer, R Keledjian, R Yang, ...
Nature immunology 5 (4), 388-392, 2004
4162004
SINCERA: a pipeline for single-cell RNA-Seq profiling analysis
M Guo, H Wang, SS Potter, JA Whitsett, Y Xu
PLoS computational biology 11 (11), e1004575, 2015
3512015
Compensatory roles of Foxa1 and Foxa2 during lung morphogenesis
H Wan, S Dingle, Y Xu, V Besnard, KH Kaestner, SL Ang, S Wert, ...
Journal of Biological Chemistry 280 (14), 13809-13816, 2005
3162005
Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms
S Xiao, N Yosef, J Yang, Y Wang, L Zhou, C Zhu, C Wu, E Baloglu, ...
Immunity 40 (4), 477-489, 2014
3112014
Hippo/Yap signaling controls epithelial progenitor cell proliferation and differentiation in the embryonic and adult lung
AW Lange, A Sridharan, Y Xu, BR Stripp, AK Perl, JA Whitsett
Journal of molecular cell biology 7 (1), 35-47, 2015
2032015
TTF-1 phosphorylation is required for peripheral lung morphogenesis, perinatal survival, and tissue-specific gene expression
M DeFelice, D Silberschmidt, R DiLauro, Y Xu, SE Wert, TE Weaver, ...
Journal of Biological Chemistry 278 (37), 35574-35583, 2003
2022003
β-Catenin regulates differentiation of respiratory epithelial cells in vivo
ML Mucenski, JM Nation, AR Thitoff, V Besnard, Y Xu, SE Wert, N Harada, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 289 (6 …, 2005
2012005
ERdj4 and ERdj5 are required for endoplasmic reticulum-associated protein degradation of misfolded surfactant protein C
M Dong, JP Bridges, K Apsley, Y Xu, TE Weaver
Molecular biology of the cell 19 (6), 2620-2630, 2008
1912008
Role of Sonic hedgehog in patterning of tracheal–bronchial cartilage and the peripheral lung
LAD Miller, SE Wert, JC Clark, Y Xu, AKT Perl, JA Whitsett
Developmental dynamics: an official publication of the American Association …, 2004
1842004
Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth
M Guo, Y Du, JJ Gokey, S Ray, SM Bell, M Adam, P Sudha, AK Perl, ...
Nature communications 10 (1), 37, 2019
1802019
C/EBPα is required for lung maturation at birth
PC Martis, JA Whitsett, Y Xu, AKT Perl, H Wan, M Ikegami
Oxford University Press for The Company of Biologists Limited 133 (6), 1155-1164, 2006
1702006
Building and regenerating the lung cell by cell
JA Whitsett, TV Kalin, Y Xu, VV Kalinichenko
Physiological reviews 99 (1), 513-554, 2019
1692019
Foxa2 is required for transition to air breathing at birth
H Wan, Y Xu, M Ikegami, MT Stahlman, KH Kaestner, SL Ang, JA Whitsett
Proceedings of the National Academy of Sciences 101 (40), 14449-14454, 2004
1632004
SLICE: determining cell differentiation and lineage based on single cell entropy
M Guo, EL Bao, M Wagner, JA Whitsett, Y Xu
Nucleic acids research 45 (7), e54-e54, 2017
1612017
KrasG12D and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lung
Y Maeda, T Tsuchiya, H Hao, DH Tompkins, Y Xu, ML Mucenski, L Du, ...
The Journal of clinical investigation 122 (12), 4388-4400, 2012
1542012
Airway epithelial SPDEF integrates goblet cell differentiation and pulmonary Th2 inflammation
P Rajavelu, G Chen, Y Xu, JA Kitzmiller, TR Korfhagen, JA Whitsett
The Journal of clinical investigation 125 (5), 2021-2031, 2015
1522015
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