| WNK3 modulates transport of Cl-in and out of cells: implications for control of cell volume and neuronal excitability KT Kahle, J Rinehart, P de Los Heros, A Louvi, P Meade, N Vazquez, ... Proceedings of the National Academy of Sciences 102 (46), 16783-16788, 2005 | 264 | 2005 |
| Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases J Ponce-Coria, P San-Cristobal, KT Kahle, N Vazquez, ... Proceedings of the National Academy of Sciences 105 (24), 8458-8463, 2008 | 229 | 2008 |
| The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+-Cl- co-transporters KTKJZ Paola de los Heros, Dario R. Alessi, Robert Gourlay, David Campbell ... Biochemical Journal 458 (3), 559-573, 2014 | 217 | 2014 |
| WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl-cotransporters required for normal blood pressure homeostasis J Rinehart, KT Kahle, P de Los Heros, N Vazquez, P Meade, FH Wilson, ... Proceedings of the National Academy of Sciences 102 (46), 16777-16782, 2005 | 215 | 2005 |
| Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and-independent pathways C Richardson, K Sakamoto, P De Los Heros, M Deak, DG Campbell, ... Journal of cell science 124 (5), 789-800, 2011 | 193 | 2011 |
| WNK3 bypasses the tonicity requirement for K-Cl cotransporter activation via a phosphatase-dependent pathway P de Los Heros, KT Kahle, J Rinehart, NA Bobadilla, N Vázquez, ... Proceedings of the National Academy of Sciences 103 (6), 1976-1981, 2006 | 153 | 2006 |
| MO25 is a master regulator of SPAK/OSR1 and MST3/MST4/YSK1 protein kinases BM Filippi, P De Los Heros, Y Mehellou, I Navratilova, R Gourlay, M Deak, ... The EMBO journal 30 (9), 1730-1741, 2011 | 144 | 2011 |
| Pathophysiology of functional mutations of the thiazide-sensitive Na-Cl cotransporter in Gitelman disease E Sabath, P Meade, J Berkman, P De Los Heros, E Moreno, NA Bobadilla, ... American Journal of Physiology-Renal Physiology 287 (2), F195-F203, 2004 | 106 | 2004 |
| WNK kinases, renal ion transport and hypertension P San-Cristobal, P De Los Heros, J Ponce-Coria, E Moreno, G Gamba American journal of nephrology 28 (5), 860-870, 2008 | 63 | 2008 |
| Ovarian hormones and prolactin increase renal NaCl cotransporter phosphorylation L Rojas-Vega, LA Reyes-Castro, V Ramírez, R Bautista-Pérez, C Rafael, ... American Journal of Physiology-Renal Physiology 308 (8), F799-F808, 2015 | 61 | 2015 |
| Functional kinomics establishes a critical node of volume-sensitive cation-Cl− cotransporter regulation in the mammalian brain J Zhang, G Gao, G Begum, J Wang, AR Khanna, BE Shmukler, ... Scientific reports 6 (1), 35986, 2016 | 49 | 2016 |
| A single nucleotide polymorphism alters the activity of the renal Na+: Cl-cotransporter and reveals a role for transmembrane segment 4 in chloride and thiazide affinity E Moreno, C Tovar-Palacio, P de los Heros, B Guzmán, NA Bobadilla, ... Journal of Biological Chemistry 279 (16), 16553-16560, 2004 | 47 | 2004 |
| N-terminal serine dephosphorylation is required for KCC3 cotransporter full activation by cell swelling Z Melo, P De Los Heros, S Cruz-Rangel, N Vázquez, NA Bobadilla, ... Journal of Biological Chemistry 288 (44), 31468-31476, 2013 | 45 | 2013 |
| Functional and molecular characterization of the K-Cl cotransporter of Xenopus laevis oocytes A Mercado, P de los Heros, N Vázquez, P Meade, DB Mount, G Gamba American Journal of Physiology-Cell Physiology 281 (2), C670-C680, 2001 | 40 | 2001 |
| Role of WNK kinases in the modulation of cell volume P de Los Heros, D Pacheco-Alvarez, G Gamba Current Topics in Membranes 81, 207-235, 2018 | 38 | 2018 |
| Physiological processes modulated by the chloride-sensitive WNK-SPAK/OSR1 kinase signaling pathway and the cation-coupled chloride cotransporters AR Murillo-de-Ozores, M Chávez-Canales, P de Los Heros, G Gamba, ... Frontiers in Physiology 11, 585907, 2020 | 37 | 2020 |
| WNK3-SPAK interaction is required for the modulation of NCC and other members of the SLC12 family D Pacheco-Alvarez, N Vázquez, M Castañeda-Bueno, P De-Los-Heros, ... Cellular Physiology and Biochemistry 29 (1-2), 291-302, 2012 | 36 | 2012 |
| Ion and diuretic specificity of chimeric proteins between apical Na+-K+-2Cl− and Na+-Cl− cotransporters C Tovar-Palacio, NA Bobadilla, P Cortés, C Plata, P de los Heros, ... American Journal of Physiology-Renal Physiology 287 (3), F570-F577, 2004 | 32 | 2004 |
| With no lysine L-WNK1 isoforms are negative regulators of the K+-Cl− cotransporters A Mercado, P de Los Heros, Z Melo, M Chávez-Canales, ... American Journal of Physiology-Cell Physiology 311 (1), C54-C66, 2016 | 15 | 2016 |
| Structure-function relationships in the renal NaCl cotransporter (NCC) E Moreno, P de Los Heros, C Plata, C Cutler, A Vega-Mateos, N Vázquez, ... Current Topics in Membranes 83, 177-204, 2019 | 13 | 2019 |
