A drug screen using human iPSC-derived hepatocyte-like cells reveals cardiac glycosides as a potential treatment for hypercholesterolemia MA Cayo, SK Mallanna, F Di Furio, R Jing, LB Tolliver, M Bures, A Urick, ... Cell Stem Cell 20 (4), 478-489. e5, 2017 | 126 | 2017 |
Metabolic regulation of inflammasome activity controls embryonic hematopoietic stem and progenitor cell production JM Frame, C Kubaczka, TL Long, V Esain, RA Soto, M Hachimi, R Jing, ... Developmental cell 55 (2), 133-149. e6, 2020 | 55 | 2020 |
A screen using iPSC-derived hepatocytes reveals NAD+ as a potential treatment for mtDNA depletion syndrome R Jing, JL Corbett, J Cai, GC Beeson, CC Beeson, SS Chan, ... Cell reports 25 (6), 1469-1484. e5, 2018 | 47 | 2018 |
EZH1 repression generates mature iPSC-derived CAR T cells with enhanced antitumor activity R Jing, I Scarfo, MA Najia, EL da Rocha, A Han, M Sanborn, T Bingham, ... Cell Stem Cell 29 (8), 1181-1196. e6, 2022 | 46 | 2022 |
FGF2 mediates hepatic progenitor cell formation during human pluripotent stem cell differentiation by inducing the WNT antagonist NKD1 K Twaroski, SK Mallanna, R Jing, F DiFurio, A Urick, SA Duncan Genes & development 29 (23), 2463-2474, 2015 | 43 | 2015 |
HNF4A regulates the formation of hepatic progenitor cells from human iPSC-derived endoderm by facilitating efficient recruitment of RNA Pol II A DeLaForest, F Di Furio, R Jing, A Ludwig-Kubinski, K Twaroski, A Urick, ... Genes 10 (1), 21, 2018 | 36 | 2018 |
A small-molecule screen reveals that HSP90β promotes the conversion of induced pluripotent stem cell-derived endoderm to a hepatic fate and regulates HNF4A turnover R Jing, CB Duncan, SA Duncan Development 144 (10), 1764-1774, 2017 | 28 | 2017 |
CellComm infers cellular crosstalk that drives haematopoietic stem and progenitor cell development E Lummertz da Rocha, C Kubaczka, WW Sugden, MA Najia, R Jing, ... Nature cell biology 24 (4), 579-589, 2022 | 13 | 2022 |
Development of functional resident macrophages in human pluripotent stem cell-derived colonic organoids and human fetal colon JO Múnera, DO Kechele, C Bouffi, N Qu, R Jing, P Maity, JR Enriquez, ... Cell Stem Cell 30 (11), 1434-1451. e9, 2023 | 5 | 2023 |
In Vivo Reprogramming of Adult Liver Sinusoidal Vascular Endothelial Cells into a Hematopoietic Stem and Progenitor Cell Niche T Han, RD Gunage, R Jing, AF Corbin, KZM Chen, Y Tang, O Stockard, ... Blood 142, 4071, 2023 | | 2023 |
Blood Flow Directs Yap/Taz-Mediated Transcriptional Regulation of Self-Renewal Programs to Control Developmental HSPC Expansion By Mechanical Stimulation of Piezo1 WW Sugden, Z LeBlanc, M Tanaka-Yano, R Jing, MG di Tillio, M Najia, ... Blood 142, 1309, 2023 | | 2023 |
950 Epigenetic reprogramming of iPSC-derived T cells for CAR T cell therapy R Jing, M Najia, E Meader, L Hensch, EL da Rocha, RG Rowe, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 1), 2023 | | 2023 |
Stroma-free t cell differentiation from human pluripotent stem cells GQ Daley, J Ran US Patent App. 17/794,747, 2023 | | 2023 |
2006–MECHANISMS OF FLOW-DRIVEN TRANSCRIPTIONAL CONTROL OF HEMATOPOIETIC STEM AND PROGENITOR CELL DEVELOPMENT BY YAP AND TAZ W Sugden, Z LeBlanc, M Yano, C Kubaczka, R Mout, M Najia, O Stockard, ... Experimental Hematology 124, S39, 2023 | | 2023 |
Prediction of intercellular communication networks using CellComm R ELd, C Kubaczka, WW Sugden, M Najia, R Jing, A Markel, Z LeBlanc, ... | | 2022 |
3097–RNA EDITOR-EXONUCLEASE AXIS SCULPTS THE TRANSCRIPTOME DURING TERMINAL ERYTHROID DIFFERENTIATION A Han, A Yermalovich, V Lundin, D Pearson, B Hilton, A Markel, P Sousa, ... Experimental Hematology 111, S93, 2022 | | 2022 |
An Essential Role for the RNA Editor-Exonuclease Axis in Terminal Erythroid Differentiation A Han, AV Yermalovich, V Lundin, DS Pearson, M Hachimi, P Sousa, ... Blood 136, 3, 2020 | | 2020 |
3090–KDM4A/C Sustain an Oncogenic Program by Epigenetic Rewiring of Oncogenic and Lineage Enhancers D Jha, G Daley, D Dominguez, MC Keogh, H Li, T Schlaeger, Y Shi, ... Experimental Hematology 88, S65-S66, 2020 | | 2020 |