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Jacob S Brenner
Jacob S Brenner
Depts. of Medicine & Pharmacology, University of Pennsylvania
Verified email at pennmedicine.upenn.edu - Homepage
Title
Cited by
Cited by
Year
Red blood cell-hitchhiking boosts delivery of nanocarriers to chosen organs by orders of magnitude
JS Brenner, DC Pan, JW Myerson, OA Marcos-Contreras, CH Villa, ...
Nature communications 9 (1), 2684, 2018
2912018
Closure device and method
JS Brenner, GA Magee, RF Peh, EI Palmer
US Patent 9,232,947, 2016
2022016
PECAM-1 directed re-targeting of exogenous mRNA providing two orders of magnitude enhancement of vascular delivery and expression in lungs independent of apolipoprotein E …
H Parhiz, VV Shuvaev, N Pardi, M Khoshnejad, RY Kiseleva, JS Brenner, ...
Journal of controlled release 291, 106-115, 2018
1232018
Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood–brain barrier
OA Marcos-Contreras, CF Greineder, RY Kiseleva, H Parhiz, LR Walsh, ...
Proceedings of the National Academy of Sciences 117 (7), 3405-3414, 2020
1192020
Nanoparticle properties modulate their attachment and effect on carrier red blood cells
DC Pan, JW Myerson, JS Brenner, PN Patel, AC Anselmo, S Mitragotri, ...
Scientific Reports 8 (1), 1615, 2018
1192018
Targeting drug delivery in the vascular system: Focus on endothelium
PM Glassman, JW Myerson, LT Ferguson, RY Kiseleva, VV Shuvaev, ...
Advanced drug delivery reviews 157, 96-117, 2020
802020
Vascular drug delivery using carrier red blood cells: focus on RBC surface loading and pharmacokinetics
PM Glassman, CH Villa, A Ukidve, Z Zhao, P Smith, S Mitragotri, ...
Pharmaceutics 12 (5), 440, 2020
742020
Red blood cell hitchhiking: a novel approach for vascular delivery of nanocarriers
JS Brenner, S Mitragotri, VR Muzykantov
Annual review of biomedical engineering 23, 225-248, 2021
682021
TrpC3 regulates hypertrophy-associated gene expression without affecting myocyte beating or cell size
JS Brenner, RE Dolmetsch
PloS one 2 (8), e802, 2007
662007
Supramolecular arrangement of protein in nanoparticle structures predicts nanoparticle tropism for neutrophils in acute lung inflammation
JW Myerson, PN Patel, KM Rubey, ME Zamora, MH Zaleski, N Habibi, ...
Nature nanotechnology 17 (1), 86-97, 2022
632022
Added to pre-existing inflammation, mRNA-lipid nanoparticles induce inflammation exacerbation (IE)
H Parhiz, JS Brenner, PN Patel, TE Papp, H Shahnawaz, Q Li, R Shi, ...
Journal of Controlled Release 344, 50-61, 2022
572022
Unintended effects of drug carriers: Big issues of small particles
H Parhiz, M Khoshnejad, JW Myerson, E Hood, PN Patel, JS Brenner, ...
Advanced drug delivery reviews 130, 90-112, 2018
572018
Neutrophils promote alveolar epithelial regeneration by enhancing type II pneumocyte proliferation in a model of acid-induced acute lung injury
AJ Paris, Y Liu, J Mei, N Dai, L Guo, LA Spruce, KM Hudock, JS Brenner, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 311 (6 …, 2016
552016
Red blood cells: The metamorphosis of a neglected carrier into the natural mothership for artificial nanocarriers
PM Glassman, ED Hood, LT Ferguson, Z Zhao, DL Siegel, S Mitragotri, ...
Advanced drug delivery reviews 178, 113992, 2021
532021
Targeted endothelial nanomedicine for common acute pathological conditions
VV Shuvaev, JS Brenner, VR Muzykantov
Journal of Controlled Release 219, 576-595, 2015
502015
Endothelial nanomedicine for the treatment of pulmonary disease
JS Brenner, C Greineder, V Shuvaev, V Muzykantov
Expert opinion on drug delivery 12 (2), 239-261, 2015
482015
Combining vascular targeting and the local first pass provides 100-fold higher uptake of ICAM-1-targeted vs untargeted nanocarriers in the inflamed brain
OA Marcos-Contreras, JS Brenner, RY Kiseleva, V Zuluaga-Ramirez, ...
Journal of controlled release 301, 54-61, 2019
402019
Mechanisms that determine nanocarrier targeting to healthy versus inflamed lung regions
JS Brenner, K Bhamidipati, PM Glassman, N Ramakrishnan, D Jiang, ...
Nanomedicine: Nanotechnology, Biology and Medicine 13 (4), 1495-1506, 2017
362017
Molecular engineering of antibodies for site-specific covalent conjugation using CRISPR/Cas9
M Khoshnejad, JS Brenner, W Motley, H Parhiz, CF Greineder, CH Villa, ...
Scientific reports 8 (1), 1760, 2018
332018
Nanomedicine to fight infectious disease
KM Rubey, JS Brenner
Advanced drug delivery reviews 179, 113996, 2021
312021
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