| Zampanolide, a potent new microtubule-stabilizing agent, covalently reacts with the taxane luminal site in tubulin α, β-heterodimers and microtubules JJ Field, B Pera, E Calvo, A Canales, D Zurwerra, C Trigili, ... Chemistry & biology 19 (6), 686-698, 2012 | 103 | 2012 |
| TRAPPII regulates exocytic Golgi exit by mediating nucleotide exchange on the Ypt31 ortholog RabERAB11 M Pinar, HN Arst Jr, A Pantazopoulou, VG Tagua, V de los Ríos, ... Proceedings of the National Academy of Sciences 112 (14), 4346-4351, 2015 | 72 | 2015 |
| Triazolopyrimidines are microtubule-stabilizing agents that bind the Vinca inhibitor site of tubulin G Sáez-Calvo, A Sharma, F de Asís Balaguer, I Barasoain, ... Cell chemical biology 24 (6), 737-750. e6, 2017 | 65 | 2017 |
| New interfacial microtubule inhibitors of marine origin, PM050489/PM060184, with potent antitumor activity and a distinct mechanism B Pera, I Barasoain, A Pantazopoulou, A Canales, R Matesanz, ... ACS chemical biology 8 (9), 2084-2094, 2013 | 59 | 2013 |
| Insights into the interaction of discodermolide and docetaxel with tubulin. Mapping the binding sites of microtubule-stabilizing agents by using an integrated NMR and … A Canales, J Rodríguez-Salarichs, C Trigili, L Nieto, C Coderch, ... ACS Chemical Biology 6 (8), 789-799, 2011 | 56 | 2011 |
| Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistances R Matesanz, C Trigili, J Rodríguez-Salarichs, I Zanardi, B Pera, A Nogales, ... Bioorganic & Medicinal Chemistry 22 (18), 5078-5090, 2014 | 39 | 2014 |
| Modulation of microtubule interprotofilament interactions by modified taxanes R Matesanz, J Rodríguez-Salarichs, B Pera, A Canales, JM Andreu, ... Biophysical journal 101 (12), 2970-2980, 2011 | 35 | 2011 |
| Structural basis of noscapine activation for tubulin binding MA Oliva, AE Prota, J Rodríguez-Salarichs, YL Bennani, ... Journal of medicinal chemistry 63 (15), 8495-8501, 2020 | 34 | 2020 |
| Molecular recognition of epothilones by microtubules and tubulin dimers revealed by biochemical and NMR approaches A Canales, L Nieto, J Rodríguez-Salarichs, PA Sanchez-Murcia, ... ACS chemical biology 9 (4), 1033-1043, 2014 | 31 | 2014 |
| Structural and biochemical characterization of the interaction of tubulin with potent natural analogues of podophyllotoxin M Antunez-Mojica, J Rodríguez-Salarichs, M Redondo-Horcajo, A León, ... Journal of natural products 79 (8), 2113-2121, 2016 | 21 | 2016 |
| Zampanolide binding to tubulin indicates cross-talk of taxane site with colchicine and nucleotide sites JJ Field, B Pera, JE Gallego, E Calvo, J Rodríguez-Salarichs, ... Journal of natural products 81 (3), 494-505, 2017 | 15 | 2017 |
| Modification of C-seco taxoids through ring tethering and substituent replacement leading to effective agents against tumor drug resistance mediated by βIII-Tubulin and P … Y Tang, J Rodríguez-Salarichs, Y Zhao, P Cai, J Estévez-Gallego, ... European Journal of Medicinal Chemistry 137, 488-503, 2017 | 14 | 2017 |
| Cañada, FJ; Jiménez-Barbero, J.; Alvarez, L.; Díaz, JF Structural and Biochemical Characterization of the Interaction of Tubulin with Potent Natural Analogues of Podophyllotoxin M Antúnez-Mojica, J Rodríguez-Salarichs, M Redondo-Horcajo, A León, ... J. Nat. Prod 79, 2113-2121, 2016 | 14 | 2016 |
| Free energy profile and kinetics studies of paclitaxel internalization from the outer to the inner wall of microtubules G Maccari, M Mori, J Rodriguez-Salarichs, W Fang, JF Díaz, M Botta Journal of Chemical Theory and Computation 9 (1), 698-706, 2013 | 12 | 2013 |
| Versatile Lipases from the Candida rugosa-like Family: A Mechanistic Insight Using Computational Approaches J Rodríguez-Salarichs, M Garcia de Lacoba, A Prieto, MJ Martínez, ... Journal of Chemical Information and Modeling 61 (2), 913-920, 2021 | 10 | 2021 |
| Improvement of the Activity of a Fungal Versatile-Lipase Toward Triglycerides: An in silico Mechanistic Description L Payá-Tormo, J Rodríguez-Salarichs, A Prieto, MJ Martínez, J Barriuso Frontiers in Bioengineering and Biotechnology 7, 71, 2019 | 8 | 2019 |
| Synthesis, Biological Profiling and Determination of the Tubulin-Bound Conformation of 12-Aza-Epothilones (Azathilones) A Jantsch, L Nieto, J Gertsch, J Rodríguez-Salarichs, R Matesanz, ... Molecules 21 (8), 1010, 2016 | 7 | 2016 |
| Synthesis, Profiling, and Bioactive Conformation of trans‐Cyclopropyl Epothilones CN Kuzniewski, S Glauser, FZ Gaugaz, R Schiess, J Rodríguez‐Salarichs, ... Helvetica Chimica Acta 102 (5), e1900078, 2019 | 6 | 2019 |
| Molecular recognition of epothilones by microtubules and tubulin dimers revealed by biochemical and NMR approaches ACS Chem A Canales, L Nieto, J Rodríguez-Salarichs, PA Sanchez-Murcia, ... Biol 9 (4), 1033-1043, 2014 | 5 | 2014 |
| High-throughput preparation of alkyl 4-aryl substituted-2-methyl-6-thioxo-1, 4, 5, 6-tetrahydropyridine-3-carboxylates under microwave irradiation H Rodriguez, J Coro, A Lam, E Salfrán, J Rodríguez-Salarichs, M Suárez, ... Arkat USA, 2011 | 5 | 2011 |
Jesus Jimenez-BarberoCIC bioGUNEVerified email at cicbiogune.es
