Glycosylation and stabilization of programmed death ligand-1 suppresses T-cell activity CW Li, SO Lim, W Xia, HH Lee, LC Chan, CW Kuo, KH Khoo, SS Chang, ... Nature communications 7 (1), 12632, 2016 | 871 | 2016 |
Deubiquitination and stabilization of PD-L1 by CSN5 SO Lim, CW Li, W Xia, JH Cha, LC Chan, Y Wu, SS Chang, WC Lin, ... Cancer cell 30 (6), 925-939, 2016 | 633 | 2016 |
Mechanisms controlling PD-L1 expression in cancer JH Cha, LC Chan, CW Li, JL Hsu, MC Hung Molecular cell 76 (3), 359-370, 2019 | 586 | 2019 |
Metformin promotes antitumor immunity via endoplasmic-reticulum-associated degradation of PD-L1 JH Cha, WH Yang, W Xia, Y Wei, LC Chan, SO Lim, CW Li, T Kim, ... Molecular cell 71 (4), 606-620. e7, 2018 | 561 | 2018 |
Eradication of triple-negative breast cancer cells by targeting glycosylated PD-L1 CW Li, SO Lim, EM Chung, YS Kim, AH Park, J Yao, JH Cha, W Xia, ... Cancer cell 33 (2), 187-201. e10, 2018 | 455 | 2018 |
Exosomal PD-L1 harbors active defense function to suppress T cell killing of breast cancer cells and promote tumor growth Y Yang, CW Li, LC Chan, Y Wei, JM Hsu, W Xia, JH Cha, J Hou, JL Hsu, ... Cell research 28 (8), 862-864, 2018 | 374 | 2018 |
STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion JM Hsu, W Xia, YH Hsu, LC Chan, WH Yu, JH Cha, CT Chen, HW Liao, ... Nature communications 9 (1), 1908, 2018 | 334 | 2018 |
Galectin-9 interacts with PD-1 and TIM-3 to regulate T cell death and is a target for cancer immunotherapy R Yang, L Sun, CF Li, YH Wang, J Yao, H Li, M Yan, WC Chang, JM Hsu, ... Nature communications 12 (1), 832, 2021 | 313 | 2021 |
IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion LC Chan, CW Li, W Xia, JM Hsu, HH Lee, JH Cha, HL Wang, WH Yang, ... The Journal of clinical investigation 129 (8), 3324-3338, 2019 | 245 | 2019 |
Hypoxia-inducible factor-1α inhibits self-renewal of mouse embryonic stem cells in vitro via negative regulation of the leukemia inhibitory factor-STAT3 pathway CH Jeong, HJ Lee, JH Cha, JH Kim, KR Kim, JH Kim, DK Yoon, KW Kim Journal of biological chemistry 282 (18), 13672-13679, 2007 | 118 | 2007 |
Targeting glycosylated PD-1 induces potent antitumor immunity L Sun, CW Li, EM Chung, R Yang, YS Kim, AH Park, YJ Lai, Y Yang, ... Cancer research 80 (11), 2298-2310, 2020 | 105 | 2020 |
Design, synthesis, and biological evaluation of novel deguelin-based heat shock protein 90 (HSP90) inhibitors targeting proliferation and angiogenesis DJ Chang, H An, K Kim, HH Kim, J Jung, JM Lee, NJ Kim, YT Han, H Yun, ... Journal of medicinal chemistry 55 (24), 10863-10884, 2012 | 100 | 2012 |
Arrest defective 1 autoacetylation is a critical step in its ability to stimulate cancer cell proliferation JH Seo, JH Cha, JH Park, CH Jeong, ZY Park, HS Lee, SH Oh, JH Kang, ... Cancer research 70 (11), 4422-4432, 2010 | 77 | 2010 |
RIPK3 activation induces TRIM28 derepression in cancer cells and enhances the anti-tumor microenvironment HH Park, HR Kim, SY Park, SM Hwang, SM Hong, S Park, HC Kang, ... Molecular Cancer 20 (1), 107, 2021 | 72 | 2021 |
Ninjurin1 deficiency attenuates susceptibility of experimental autoimmune encephalomyelitis in mice BJ Ahn, H Le, MW Shin, SJ Bae, EJ Lee, HJ Wee, JH Cha, HJ Lee, ... Journal of Biological Chemistry 289 (6), 3328-3338, 2014 | 55 | 2014 |
Identification, biological activity, and mechanism of the anti-ischemic quinolone analog CH Park, J Lee, HY Jung, MJ Kim, SH Lim, HT Yeo, EC Choi, EJ Yoon, ... Bioorganic & medicinal chemistry 15 (20), 6517-6526, 2007 | 43 | 2007 |
AKAP12 induces apoptotic cell death in human fibrosarcoma cells by regulating CDKI-cyclin D1 and caspase-3 activity DK Yoon, CH Jeong, HO Jun, KH Chun, JH Cha, JH Seo, HY Lee, ... Cancer letters 254 (1), 111-118, 2007 | 43 | 2007 |
AKAP12 mediates barrier functions of fibrotic scars during CNS repair JH Cha, HJ Wee, JH Seo, BJ Ahn, JH Park, JM Yang, SW Lee, EH Kim, ... PloS one 9 (4), e94695, 2014 | 38 | 2014 |
Prompt meningeal reconstruction mediated by oxygen-sensitive AKAP12 scaffolding protein after central nervous system injury JH Cha, HJ Wee, JH Seo, B Ju Ahn, JH Park, JM Yang, SW Lee, OH Lee, ... Nature communications 5 (1), 4952, 2014 | 36 | 2014 |
TMEM9‐v‐ATPase activates Wnt/β‐catenin signaling via APC lysosomal degradation for liver regeneration and tumorigenesis YS Jung, SA Stratton, SH Lee, MJ Kim, S Jun, J Zhang, B Zheng, ... Hepatology 73 (2), 776-794, 2021 | 35 | 2021 |