| A selective TrkB agonist with potent neurotrophic activities by 7, 8-dihydroxyflavone SW Jang, X Liu, M Yepes, KR Shepherd, GW Miller, Y Liu, WD Wilson, ... Proceedings of the National Academy of Sciences 107 (6), 2687-2692, 2010 | 705 | 2010 |
| Tissue-type plasminogen activator induces opening of the blood-brain barrier via the LDL receptor–related protein M Yepes, M Sandkvist, EG Moore, TH Bugge, DK Strickland, ... The Journal of clinical investigation 112 (10), 1533-1540, 2003 | 694 | 2003 |
| Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke EJ Su, L Fredriksson, M Geyer, E Folestad, J Cale, J Andrae, Y Gao, ... Nature medicine 14 (7), 731-737, 2008 | 513 | 2008 |
| Neuroserpin reduces cerebral infarct volume and protects neurons from ischemia-induced apoptosis M Yepes, M Sandkvist, MKK Wong, TA Coleman, E Smith, SL Cohan, ... Blood, The Journal of the American Society of Hematology 96 (2), 569-576, 2000 | 366 | 2000 |
| Tissue-type plasminogen activator in the ischemic brain: more than a thrombolytic M Yepes, BD Roussel, C Ali, D Vivien Trends in neurosciences 32 (1), 48-55, 2009 | 348 | 2009 |
| p38 MAPK inhibits autophagy and promotes microglial inflammatory responses by phosphorylating ULK1 Y He, H She, T Zhang, H Xu, L Cheng, M Yepes, Y Zhao, Z Mao Journal of Cell Biology 217 (1), 315-328, 2018 | 231 | 2018 |
| Tissue-type plasminogen activator–mediated shedding of astrocytic low-density lipoprotein receptor–related protein increases the permeability of the neurovascular unit R Polavarapu, MC Gongora, H Yi, S Ranganthan, DA Lawrence, ... Blood 109 (8), 3270-3278, 2007 | 198 | 2007 |
| Regulation of seizure spreading by neuroserpin and tissue-type plasminogen activator is plasminogen-independent M Yepes, M Sandkvist, TA Coleman, E Moore, JY Wu, D Mitola, TH Bugge, ... The Journal of clinical investigation 109 (12), 1571-1578, 2002 | 187 | 2002 |
| Association between conformational mutations in neuroserpin and onset and severity of dementia RL Davis, AE Shrimpton, RW Carrell, DA Lomas, L Gerhard, B Baumann, ... The Lancet 359 (9325), 2242-2247, 2002 | 174 | 2002 |
| Adjuvant treatment with neuroserpin increases the therapeutic window for tissue-type plasminogen activator administration in a rat model of embolic stroke Z Zhang, L Zhang, M Yepes, Q Jiang, Q Li, P Arniego, TA Coleman, ... Circulation 106 (6), 740-745, 2002 | 157 | 2002 |
| Interaction of Akt-phosphorylated SRPK2 with 14-3-3 mediates cell cycle and cell death in neurons SW Jang, X Liu, H Fu, H Rees, M Yepes, A Levey, K Ye Journal of Biological Chemistry 284 (36), 24512-24525, 2009 | 153 | 2009 |
| A soluble Fn14-Fc decoy receptor reduces infarct volume in a murine model of cerebral ischemia M Yepes, SAN Brown, EG Moore, EP Smith, DA Lawrence, JA Winkles The American journal of pathology 166 (2), 511-520, 2005 | 143 | 2005 |
| Tumor necrosis factor-like weak inducer of apoptosis increases the permeability of the neurovascular unit through nuclear factor-κB pathway activation R Polavarapu, MC Gongora, JA Winkles, M Yepes Journal of Neuroscience 25 (44), 10094-10100, 2005 | 142 | 2005 |
| Identification of a novel small molecule HIF-1α translation inhibitor T Narita, S Yin, CF Gelin, CS Moreno, M Yepes, KC Nicolaou, ... Clinical Cancer Research 15 (19), 6128-6136, 2009 | 140 | 2009 |
| Neuroprotective actions of PIKE-L by inhibition of SET proteolytic degradation by asparagine endopeptidase Z Liu, SW Jang, X Liu, D Cheng, J Peng, M Yepes, X Li, S Matthews, ... Molecular cell 29 (6), 665-678, 2008 | 133 | 2008 |
| The role of plasminogen activators in stroke treatment: fibrinolysis and beyond AM Thiebaut, M Gauberti, C Ali, SM De Lizarrondo, D Vivien, M Yepes, ... The Lancet Neurology 17 (12), 1121-1132, 2018 | 114 | 2018 |
| Neuroserpin: a selective inhibitor of tissue-type plasminogen activator in the central nervous system M Yepes, DA Lawrence Thrombosis and haemostasis 91 (03), 457-464, 2004 | 114 | 2004 |
| Tissue-type plasminogen activator is a neuroprotectant in the mouse hippocampus R Echeverry, J Wu, WB Haile, J Guzman, M Yepes The Journal of clinical investigation 120 (6), 2194-2205, 2010 | 112 | 2010 |
| Tissue-type plasminogen activator and the low-density lipoprotein receptor-related protein mediate cerebral ischemia-induced nuclear factor-κB pathway activation X Zhang, R Polavarapu, H She, Z Mao, M Yepes The American journal of pathology 171 (4), 1281-1290, 2007 | 111 | 2007 |
| TWEAK—Fn14 Pathway Inhibition Protects the Integrity of the Neurovascular Unit during Cerebral Ischemia X Zhang, JA Winkles, MC Gongora, R Polavarapu, JS Michaelson, ... Journal of Cerebral Blood Flow & Metabolism 27 (3), 534-544, 2007 | 110 | 2007 |
