| Exploitation of the adsorptive properties of depth filters for host cell protein removal during monoclonal antibody purification Y Yigzaw, R Piper, M Tran, AA Shukla Biotechnology progress 22 (1), 288-296, 2006 | 215 | 2006 |
| The C terminus of sprouty is important for modulation of cellular migration and proliferation Y Yigzaw, L Cartin, S Pierre, K Scholich, TB Patel Journal of Biological Chemistry 276 (25), 22742-22747, 2001 | 135 | 2001 |
| Caprylic acid precipitation method for impurity reduction: an alternative to conventional chromatography for monoclonal antibody purification Y Brodsky, C Zhang, Y Yigzaw, G Vedantham Biotechnology and Bioengineering 109 (10), 2589-2598, 2012 | 90 | 2012 |
| Transmodulation of epidermal growth factor receptor function by cyclic AMP-dependent protein kinase AJ Barbier, HM Poppleton, Y Yigzaw, JB Mullenix, GJ Wiepz, PJ Bertics, ... Journal of Biological Chemistry 274 (20), 14067-14073, 1999 | 74 | 1999 |
| Regions on adenylyl cyclase that are necessary for inhibition of activity by βγ and Giα subunits of heterotrimeric G proteins C Wittpoth, K Scholich, Y Yigzaw, TM Stringfield, TB Patel Proceedings of the National Academy of Sciences 96 (17), 9551-9556, 1999 | 63 | 1999 |
| Protein-tyrosine phosphatase-1B (PTP1B) mediates the anti-migratory actions of Sprouty Y Yigzaw, HM Poppleton, N Sreejayan, A Hassid, TB Patel Journal of Biological Chemistry 278 (1), 284-288, 2003 | 57 | 2003 |
| Ion exchange chromatography of proteins and clearance of aggregates Y Yigzaw, P Hinckley, A Hewig, G Vedantham Current pharmaceutical biotechnology 10 (4), 421-426, 2009 | 53 | 2009 |
| Hydrophobic interaction chromatography in dual salt system increases protein binding capacity AM Senczuk, R Klinke, T Arakawa, G Vedantham, Y Yigzaw Biotechnology and bioengineering 103 (5), 930-935, 2009 | 44 | 2009 |
| Strategies to address aggregation during protein A chromatography AA Shukla, PJ Hinckley, P Gupta, Y Yigzaw, B Hubbard BioProcess Int 3 (5), 36-43, 2005 | 38 | 2005 |
| A rapid high-sensitivity reversed–phase ultra high performance liquid chromatography mass spectrometry method for assessing polysorbate 20 degradation in protein therapeutics Y Cheng, M Hu, C Zamiri, T Carcelen, B Demeule, A Tomlinson, J Gu, ... Journal of Pharmaceutical Sciences 108 (9), 2880-2886, 2019 | 24 | 2019 |
| Isolation and characterization of an α-macroglobulin from the gastropod mollusc Helix pomatia with tetrameric structure and preserved activity after methylamine treatment Y Yigzaw, C Gielens, G Préaux Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 2001 | 19 | 2001 |
| Modes of preparative chromatography AA Shukla, Y Yigzaw Process scale bioseparations for the biopharmaceutical industry, 201-248, 2006 | 16 | 2006 |
| Involvement of glycans in the immunological cross-reaction between α-macroglobulin and hemocyanin of the gastropod Helix pomatia NI Siddiqui, Y Yigzaw, G Préaux, C Gielens Biochimie 91 (4), 508-516, 2009 | 15 | 2009 |
| Towards continuous mAb purification: Clearance of host cell proteins from CHO cell culture harvests via “flow‐through affinity chromatography” using peptide‐based adsorbents SA Sripada, W Chu, TI Williams, MA Teten, BJ Mosley, RG Carbonell, ... Biotechnology and Bioengineering 119 (7), 1873-1889, 2022 | 14 | 2022 |
| Method for using light scattering in real time to directly monitor and control impurity removal in purification processes AC Hewig III, DH Phan, Y Yigzaw, R Bailey US Patent 10,481,164, 2019 | 12 | 2019 |
| Functional analyses of type V adenylyl cyclase. TB Patel, C Wittpoth, AJ Barbier, Y Yigzaw, K Scholich Methods in Enzymology 345, 160-187, 2002 | 11 | 2002 |
| Characterization and implications of host‐cell protein aggregates in biopharmaceutical processing YH Oh, ML Becker, KM Mendola, LH Choe, L Min, KH Lee, Y Yigzaw, ... Biotechnology and Bioengineering 120 (4), 1068-1080, 2023 | 8 | 2023 |
| Evaluation of predictive tools for cell culture clarification performance A Senczuk, K Petty, A Thomas, T McNerney, J Moscariello, Y Yigzaw Biotechnology and Bioengineering 113 (3), 568-575, 2016 | 7 | 2016 |
| Identification and characterization of CHO host‐cell proteins in monoclonal antibody bioprocessing YH Oh, KM Mendola, LH Choe, L Min, AR Lavoie, SA Sripada, TI Williams, ... Biotechnology and Bioengineering 121 (1), 291-305, 2024 | 5 | 2024 |
| Purification of multispecific antibodies GS Giese, E Rosenberg, B Sallier, S Konrad, W Koehnlein, S Willmann, ... US Patent App. 16/221,369, 2019 | 3 | 2019 |
