| N6-Methyladenosine–binding proteins suppress HIV-1 infectivity and viral production W Lu, N Tirumuru, CS Gelais, PC Koneru, C Liu, M Kvaratskhelia, C He, ... Journal of Biological Chemistry 293 (34), 12992-13005, 2018 | 100 | 2018 |
| HIV-1 integrase tetramers are the antiviral target of pyridine-based allosteric integrase inhibitors PC Koneru, AC Francis, N Deng, SV Rebensburg, AC Hoyte, ... Elife 8, e46344, 2019 | 44 | 2019 |
| Integrase-RNA interactions underscore the critical role of integrase in HIV-1 virion morphogenesis JL Elliott, JE Eschbach, PC Koneru, W Li, M Puray-Chavez, D Townsend, ... Elife 9, e54311, 2020 | 42 | 2020 |
| Indole-based allosteric inhibitors of HIV-1 integrase. FJR Patel PA, Kvaratskhelia N, Mansour Y, Antwi J, Feng L, Koneru P, Kobe MJ ... Bioorg Med Chem Lett, 2016 | 36 | 2016 |
| Allosteric HIV-1 integrase inhibitors lead to premature degradation of the viral RNA genome and integrase in target cells MK Madison, DQ Lawson, J Elliott, AN Ozantürk, PC Koneru, D Townsend, ... Journal of virology 91 (17), 10.1128/jvi. 00821-17, 2017 | 35 | 2017 |
| Resistance to pyridine-based inhibitor KF116 reveals an unexpected role of integrase in HIV-1 Gag-Pol polyprotein proteolytic processing AC Hoyte, AV Jamin, PC Koneru, MJ Kobe, RC Larue, JR Fuchs, ... Journal of Biological Chemistry 292 (48), 19814-19825, 2017 | 32 | 2017 |
| A New Class of Allosteric HIV-1 Integrase Inhibitors Identified by Crystallographic Fragment Screening of the Catalytic Core Domain. AE Patel D, Antwi J, Koneru PC, Serrao E, Forli S, Kessl JJ, Feng L, Deng N ... Journal of biological chemistry, 23569-23577, 2016 | 25 | 2016 |
| An isoquinoline scaffold as a novel class of allosteric HIV-1 integrase inhibitors TA Wilson, PC Koneru, SV Rebensburg, JJ Lindenberger, MJ Kobe, ... ACS Medicinal Chemistry Letters 10 (2), 215-220, 2019 | 20 | 2019 |
| Discovery of dihydroxyindole-2-carboxylic acid derivatives as dual allosteric HIV-1 Integrase and Reverse Transcriptase associated Ribonuclease H inhibitors F Esposito, M Sechi, N Pala, A Sanna, PC Koneru, M Kvaratskhelia, ... Antiviral Research 174, 104671, 2020 | 18 | 2020 |
| A highly potent and safe pyrrolopyridine-based allosteric HIV-1 integrase inhibitor targeting host LEDGF/p75-integrase interaction site T Maehigashi, S Ahn, UI Kim, J Lindenberger, A Oo, PC Koneru, ... PLoS pathogens 17 (7), e1009671, 2021 | 17 | 2021 |
| Thermodynamic instability of viral proteins is a pathogen-associated molecular pattern targeted by human defensins. KDS Kudryashova E, Koneru PC, Kvaratskhelia M, Strömstedt AA, Lu W Scientific Reports, 2016 | 10 | 2016 |
| HIV-1 integrase binding to genomic RNA 5′-UTR induces local structural changes in vitro and in virio S Liu, PC Koneru, W Li, C Pathirage, AN Engelman, M Kvaratskhelia, ... Retrovirology 18, 1-16, 2021 | 7 | 2021 |
| Identification and optimization of a novel HIV-1 integrase inhibitor D Adu-Ampratwum, Y Pan, PC Koneru, J Antwi, AC Hoyte, J Kessl, ... ACS omega 7 (5), 4482-4491, 2022 | 4 | 2022 |
| Structural studies and biological evaluation of T30695 variants modified with single chiral glycerol-T reveal the importance of LEDGF/p75 for the aptamer anti-HIV-integrase … E Rivieccio, L Tartaglione, V Esposito, C Dell'Aversano, PC Koneru, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1863 (2), 351-361, 2019 | 3 | 2019 |
| Mechanistic and structural investigations into the mode of action of allosteric HIV-1 integrase inhibitors PC Koneru The Ohio State University, 2019 | 2 | 2019 |
| N6-methyladenosine Binding Proteins Negatively Regulate HIV-1 Infectivity and Viral Production W Lu, N Tirumuru, PC Koneru, C Liu, M Kvaratskhelia, C He, L Wu bioRxiv, 257410, 2018 | 1 | 2018 |
| Interaction between HIV-1 integrase and viral RNA drives proper virion morphogenesis and is necessary for successful infection JL Elliott, JE Eschbach, DQ Lawson, M Puray-Chavez, D Townsend, W Li, ... The Journal of Immunology 202 (1_Supplement), 197.21-197.21, 2019 | | 2019 |
| Synthesis of novel allosteric inhibitors of HIV-1 integrase that bind to the LEDGF/p75 site Y Mansour, P Koneru, M Kobe, A Hoyte, MS Mohamed, M Kvaratskhelia, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016 | | 2016 |
| Elaboration of indole frameworks in the development of allosteric HIV-1 integrase inhibitors J Antwi, P Koneru, M Kobe, M Kvaratskhelia, J Fuchs ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 252, 2016 | | 2016 |
| HIV-1 Integrase Tetramers are the Antiviral Target of Pyridine-based Allosteric Integrase 1 Inhibitors 2 C Hoyte, J Lindenberger, D Adu-Ampratwum, RC Larue, MF Wempe, ... | | |
