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L. Michel Espinoza-Fonseca
L. Michel Espinoza-Fonseca
Internal Medicine - Cardiology, University of Michigan
Verified email at umich.edu - Homepage
Title
Cited by
Cited by
Year
The benefits of the multi-target approach in drug design and discovery
LM Espinoza-Fonseca
Bioorganic & medicinal chemistry 14 (4), 896-897, 2006
1692006
Reconciling binding mechanisms of intrinsically disordered proteins
LM Espinoza-Fonseca
Biochemical and biophysical research communications 382 (3), 479-482, 2009
1132009
Phosphorylation-induced structural changes in smooth muscle myosin regulatory light chain
D Kast, LM Espinoza-Fonseca, C Yi, DD Thomas
Proceedings of the National Academy of Sciences 107 (18), 8207-8212, 2010
932010
Molecular dynamics simulations reveal a disorder-to-order transition on phosphorylation of smooth muscle myosin
LM Espinoza-Fonseca, D Kast, DD Thomas
Biophysical journal 93 (6), 2083-2090, 2007
712007
Docking and quantum mechanic studies on cholinesterases and their inhibitors
J Correa-Basurto, C Flores-Sandoval, J Marín-Cruz, A Rojo-Domínguez, ...
European journal of medicinal chemistry 42 (1), 10-19, 2007
712007
Synthesis, anticholinesterase activity and structure–activity relationships of m-aminobenzoic acid derivatives
J Trujillo-Ferrara, LM Cano, M Espinoza-Fonseca
Bioorganic & medicinal chemistry letters 13 (10), 1825-1827, 2003
682003
Thermodynamic and structural basis of phosphorylation-induced disorder-to-order transition in the regulatory light chain of smooth muscle myosin
LM Espinoza-Fonseca, D Kast, DD Thomas
Journal of the American Chemical Society 130 (37), 12208-12209, 2008
642008
Atomic-level characterization of the activation mechanism of SERCA by calcium
LM Espinoza-Fonseca, DD Thomas
PLoS One 6 (10), e26936, 2011
632011
Site-directed spectroscopy of cardiac myosin-binding protein C reveals effects of phosphorylation on protein structural dynamics
BA Colson, AR Thompson, LM Espinoza-Fonseca, DD Thomas
Proceedings of the National Academy of Sciences 113 (12), 3233-3238, 2016
562016
Targeting MDM2 by the small molecule RITA: towards the development of new multi-target drugs against cancer
LM Espinoza-Fonseca
Theoretical Biology and Medical Modelling 2, 1-6, 2005
562005
p–Aminobenzoic acid derivatives as acetylcholinesterase inhibitors
J Correa-Basurto, IV Alcántara, LM Espinoza-Fonseca, JG Trujillo-Ferrara
European journal of medicinal chemistry 40 (7), 732-735, 2005
542005
Conformational changes of the p53‐binding cleft of MDM2 revealed by molecular dynamics simulations
LM Espinoza‐Fonseca, JG Trujillo‐Ferrara
Biopolymers: Original Research on Biomolecules 83 (4), 365-373, 2006
532006
Sarcolipin Promotes Uncoupling of the SERCA Ca2+ Pump by Inducing a Structural Rearrangement in the Energy-Transduction Domain
JM Autry, DD Thomas, LM Espinoza-Fonseca
Biochemistry 55 (44), 6083-6086, 2016
462016
Linking biochemical and structural states of SERCA: achievements, challenges, and new opportunities
R Aguayo-Ortiz, LM Espinoza-Fonseca
International Journal of Molecular Sciences 21 (11), 4146, 2020
442020
Microsecond Molecular Dynamics Simulations of Mg2+- and K+- Bound E1 Intermediate States of the Calcium Pump
LM Espinoza-Fonseca, JM Autry, DD Thomas
PLoS One 9 (4), e95979, 2014
412014
Atomic-level mechanisms for phospholamban regulation of the calcium pump
LM Espinoza-Fonseca, JM Autry, GL Ramírez-Salinas, DD Thomas
Biophysical journal 108 (7), 1697-1708, 2015
402015
Sarcolipin and phospholamban inhibit the calcium pump by populating a similar metal ion-free intermediate state
LM Espinoza-Fonseca, JM Autry, DD Thomas
Biochemical and biophysical research communications 463 (1-2), 37-41, 2015
382015
Aromatic residues link binding and function of intrinsically disordered proteins
LM Espinoza-Fonseca
Molecular BioSystems 8 (1), 237-246, 2012
382012
Nothing regular about the regulins: Distinct functional properties of SERCA transmembrane peptide regulatory subunits
N Rathod, JJ Bak, JO Primeau, MLE Fisher, LM Espinoza-Fonseca, ...
International Journal of Molecular Sciences 22 (16), 8891, 2021
342021
The phospholamban pentamer alters function of the sarcoplasmic reticulum calcium pump SERCA
JP Glaves, JO Primeau, LM Espinoza-Fonseca, MJ Lemieux, HS Young
Biophysical journal 116 (4), 633-647, 2019
322019
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Articles 1–20