Highly efficient DSB-free base editing for streptomycetes with CRISPR-BEST Y Tong, CM Whitford, HL Robertsen, K Blin, TS Jørgensen, AK Klitgaard, ... Proceedings of the National Academy of Sciences 116 (41), 20366-20375, 2019 | 143 | 2019 |
CRISPR–Cas9, CRISPRi and CRISPR-BEST-mediated genetic manipulation in streptomycetes Y Tong, CM Whitford, K Blin, TS Jørgensen, T Weber, SY Lee Nature Protocols, 1-33, 2020 | 63 | 2020 |
A versatile genetic engineering toolkit for E. coli based on CRISPR-prime editing Y Tong, TS Jørgensen, CM Whitford, T Weber, SY Lee Nature communications 12 (1), 5206, 2021 | 60 | 2021 |
Auxotrophy to Xeno-DNA: an exploration of combinatorial mechanisms for a high-fidelity biosafety system for synthetic biology applications CM Whitford, S Dymek, D Kerkhoff, C März, O Schmidt, M Edich, J Droste, ... Journal of Biological Engineering 12, 1-28, 2018 | 34 | 2018 |
The design-build-test-learn cycle for metabolic engineering of streptomycetes CM Whitford, P Cruz-Morales, JD Keasling, T Weber Essays in biochemistry 65 (2), 261-275, 2021 | 22 | 2021 |
Characterization and engineering of Streptomyces griseofuscus DSM 40191 as a potential host for heterologous expression of biosynthetic gene clusters T Gren, CM Whitford, OS Mohite, TS Jørgensen, EE Kontou, JB Nielsen, ... Scientific Reports 11 (1), 18301, 2021 | 13 | 2021 |
Synthetic biology ethics at iGEM: iGEMer perspectives CM Whitford, NC Lübke, C Rückert Trends in Biotechnology 36 (10), 985-987, 2018 | 9 | 2018 |
High-quality sequencing, assembly, and annotation of the Streptomyces griseofuscus DSM 40191 genome T Gren, TS Jørgensen, CM Whitford, T Weber Microbiology Resource Announcements 9 (47), 10.1128/mra. 01100-20, 2020 | 8 | 2020 |
Characterization and Engineering ofStreptomyces griseofuscusDSM 40191 as a Potential Host for Heterologous Expression of Biosynthetic Gene Clusters T Gren, CM Whitford, OS Mohite, TS Jørgensen, EE Kontou, JB Nielsen, ... | 3 | 2020 |
Biosynthesis of the Azoxy Compound Azodyrecin from Streptomyces mirabilis P8-A2 M Maleckis, M Wibowo, T Gren, SA Jarmusch, EB Sterndorff, T Booth, ... ACS chemical biology, 2024 | 2 | 2024 |
Systems Analysis of Highly Multiplexed CRISPR-Base Editing in Streptomycetes CM Whitford, T Gren, E Palazzotto, SY Lee, Y Tong, T Weber ACS Synthetic Biology 12 (8), 2353-2366, 2023 | 2 | 2023 |
CASCADE-Cas3 Enables Highly Efficient Genome Engineering in Streptomyces Species CM Whitford, P Gockel, D Faurdal, T Gren, R Sigrist, T Weber bioRxiv, 2023.05. 09.539971, 2023 | 2 | 2023 |
Expanding the genetic code L Karsten, D Bergen, C Drake, S Dymek, M Edich, M Haak, D Kerkhoff, ... | 2 | 2017 |
Heterologous production of polycyclopropanated fatty acids and their methyl esters in Streptomyces K Yin, P Cruz-Morales, CM Whitford, JD Keasling STAR protocols 4 (2), 102190, 2023 | | 2023 |
Development of CRISPR Tools for Metabolic Engineering of Specialized Metabolite Production in Streptomyces CM Whitford Technical University of Denmark, 2023 | | 2023 |
CRISPR-nRAGE, a Cas9 nickase-reverse transcriptase assisted versatile genetic engineering toolkit for E. coli Y Tong, TS Jørgensen, CM Whitford, T Weber, SY Lee bioRxiv, 2020.09. 02.279141, 2020 | | 2020 |