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Chunyu Wang
Chunyu Wang
Professor of Biological Sciences, Chemistry and Chemical Biology, Rensselaer Polytechnic Institute
Verified email at rpi.edu - Homepage
Title
Cited by
Cited by
Year
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease
H Du, L Guo, F Fang, D Chen, A A Sosunov, G M McKhann, Y Yan, ...
Nature medicine 14 (10), 1097-1105, 2008
10112008
Amyloid β protein and Alzheimer’s disease: When computer simulations complement experimental studies
J Nasica-Labouze, PH Nguyen, F Sterpone, O Berthoumieu, NV Buchete, ...
Chemical reviews 115 (9), 3518-3563, 2015
6062015
The Alzheimer’s peptides Aβ40 and 42 adopt distinct conformations in water: a combined MD/NMR study
NG Sgourakis, Y Yan, SA McCallum, C Wang, AE Garcia
Journal of molecular biology 368 (5), 1448-1457, 2007
5062007
Lysine-specific molecular tweezers are broad-spectrum inhibitors of assembly and toxicity of amyloid proteins
S Sinha, DHJ Lopes, Z Du, ES Pang, A Shanmugam, A Lomakin, ...
Journal of the American Chemical Society 133 (42), 16958-16969, 2011
3352011
Aβ42 is more rigid than Aβ40 at the C terminus: implications for Aβ aggregation and toxicity
Y Yan, C Wang
Journal of molecular biology 364 (5), 853-862, 2006
3272006
Rational stabilization of enzymes by computational redesign of surface charge–charge interactions
AV Gribenko, MM Patel, J Liu, SA McCallum, C Wang, GI Makhatadze
Proceedings of the National Academy of Sciences 106 (8), 2601-2606, 2009
2752009
Atomic-level characterization of the ensemble of the Aβ (1–42) monomer in water using unbiased molecular dynamics simulations and spectral algorithms
NG Sgourakis, M Merced-Serrano, C Boutsidis, P Drineas, Z Du, C Wang, ...
Journal of molecular biology 405 (2), 570-583, 2011
2402011
Aβ monomers transiently sample oligomer and fibril-like configurations: Ensemble characterization using a combined MD/NMR approach
DJ Rosenman, CR Connors, W Chen, C Wang, AE García
Journal of molecular biology 425 (18), 3338-3359, 2013
2392013
NMR R 1ρ rotating-frame relaxation with weak radio frequency fields
F Massi, E Johnson, C Wang, M Rance, AG Palmer
Journal of the American Chemical Society 126 (7), 2247-2256, 2004
1792004
Disulfide bond isomerization in basic pancreatic trypsin inhibitor: multisite chemical exchange quantified by CPMG relaxation dispersion and chemical shift modeling
MJ Grey, C Wang, AG Palmer
Journal of the American Chemical Society 125 (47), 14324-14335, 2003
1732003
EGCG binds intrinsically disordered N-terminal domain of p53 and disrupts p53-MDM2 interaction
J Zhao, A Blayney, X Liu, L Gandy, W Jin, L Yan, JH Ha, AJ Canning, ...
Nature communications 12 (1), 986, 2021
1552021
γ-Secretase substrate concentration modulates the Aβ42/Aβ40 ratio: Implications for Alzheimer disease
YI Yin, B Bassit, L Zhu, X Yang, C Wang, YM Li
Journal of Biological Chemistry 282 (32), 23639-23644, 2007
1522007
Comparison of Three Amyloid Assembly Inhibitors: The Sugar scyllo-Inositol, the Polyphenol Epigallocatechin Gallate, and the Molecular Tweezer CLR01
S Sinha, Z Du, P Maiti, FG Klärner, T Schrader, C Wang, G Bitan
ACS chemical neuroscience 3 (6), 451-458, 2012
1422012
Identification of the peptide sequences within the EIIIA (EDA) segment of fibronectin that mediate integrin α9β1-dependent cellular activities
AV Shinde, C Bystroff, C Wang, MG Vogelezang, PA Vincent, RO Hynes, ...
Journal of Biological Chemistry 283 (5), 2858-2870, 2008
1302008
Solution NMR spin relaxation methods for characterizing chemical exchange in high-molecular-weight systems
AG Palmer III, MJ Grey, C Wang
Methods in enzymology 394, 430-465, 2005
1262005
Solution structure of ThiS and implications for the evolutionary roots of ubiquitin
C Wang, J Xi, TP Begley, LK Nicholson
Nature structural biology 8 (1), 47-51, 2001
1252001
Aβ40 protects non-toxic Aβ42 monomer from aggregation
Y Yan, C Wang
Journal of molecular biology 369 (4), 909-916, 2007
1222007
The role of backbone motions in ligand binding to the c-Src SH3 domain
C Wang, NH Pawley, LK Nicholson
Journal of molecular biology 313 (4), 873-887, 2001
1142001
Mapping chemical exchange in proteins with MW> 50 kD
C Wang, M Rance, AG Palmer
Journal of the American Chemical Society 125 (30), 8968-8969, 2003
1072003
Targeting amyloidogenic processing of APP in Alzheimer’s disease
J Zhao, X Liu, W Xia, Y Zhang, C Wang
Frontiers in molecular neuroscience 13, 137, 2020
992020
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