| Drugs for bad bugs: confronting the challenges of antibacterial discovery DJ Payne, MN Gwynn, DJ Holmes, DL Pompliano Nature reviews Drug discovery 6 (1), 29-40, 2007 | 2911 | 2007 |
| Alternatives to antibiotics—a pipeline portfolio review L Czaplewski, R Bax, M Clokie, M Dawson, H Fairhead, VA Fischetti, ... The Lancet infectious diseases 16 (2), 239-251, 2016 | 910 | 2016 |
| Crystal Structure of the IMP-1 Metallo β-Lactamase from Pseudomonas aeruginosa and Its Complex with a Mercaptocarboxylate Inhibitor: Binding Determinants of a Potent … NO Concha, CA Janson, P Rowling, S Pearson, CA Cheever, BP Clarke, ... Biochemistry 39 (15), 4288-4298, 2000 | 383 | 2000 |
| Crystal Structure of the Zinc-Dependent β-Lactamase from Bacillus cereus at 1.9 Å Resolution: Binuclear Active Site with Features of a Mononuclear Enzyme, SM Fabiane, MK Sohi, T Wan, DJ Payne, JH Bateson, T Mitchell, ... Biochemistry 37 (36), 12404-12411, 1998 | 290 | 1998 |
| Challenges of antibacterial discovery revisited MN Gwynn, A Portnoy, SF Rittenhouse, DJ Payne Annals of the New York Academy of Sciences 1213 (1), 5-19, 2010 | 242 | 2010 |
| Comparative activities of clavulanic acid, sulbactam, and tazobactam against clinically important beta-lactamases DJ Payne, R Cramp, DJ Winstanley, DJ Knowles Antimicrobial agents and chemotherapy 38 (4), 767-772, 1994 | 235 | 1994 |
| Desperately seeking new antibiotics DJ Payne Science 321 (5896), 1644-1645, 2008 | 214 | 2008 |
| Discovery of a novel and potent class of FabI-directed antibacterial agents DJ Payne, WH Miller, V Berry, J Brosky, WJ Burgess, E Chen, ... Antimicrobial agents and chemotherapy 46 (10), 3118-3124, 2002 | 204 | 2002 |
| Bacterial fatty-acid biosynthesis: a genomics-driven target for antibacterial drug discovery DJ Payne, PV Warren, DJ Holmes, Y Ji, JT Lonsdale Drug discovery today 6 (10), 537-544, 2001 | 203 | 2001 |
| Indole naphthyridinones as inhibitors of bacterial enoyl-ACP reductases FabI and FabK MA Seefeld, WH Miller, KA Newlander, WJ Burgess, WE DeWolf, ... Journal of medicinal chemistry 46 (9), 1627-1635, 2003 | 199 | 2003 |
| Technologies to address antimicrobial resistance SJ Baker, DJ Payne, R Rappuoli, E De Gregorio Proceedings of the National Academy of Sciences 115 (51), 12887-12895, 2018 | 188 | 2018 |
| Inhibition of metallo-beta-lactamases by a series of mercaptoacetic acid thiol ester derivatives DJ Payne, JH Bateson, BC Gasson, D Proctor, T Khushi, TH Farmer, ... Antimicrobial agents and chemotherapy 41 (1), 135-140, 1997 | 184 | 1997 |
| Dictionary of antibiotics and related substances: with CD-ROM BW Bycroft, DJ Payne CRC Press, 2013 | 183 | 2013 |
| Metallo-β-lactamases—a new therapeutic challenge DJ Payne Journal of Medical Microbiology 39 (2), 93-99, 1993 | 173 | 1993 |
| Two Active Forms of UDP-N-Acetylglucosamine Enolpyruvyl Transferase in Gram-Positive Bacteria W Du, JR Brown, DR Sylvester, J Huang, AF Chalker, CY So, DJ Holmes, ... Journal of Bacteriology 182 (15), 4146-4152, 2000 | 162 | 2000 |
| Defining and Combating the Mechanisms of Triclosan Resistance in Clinical Isolates of Staphylococcus aureus F Fan, K Yan, NG Wallis, S Reed, TD Moore, SF Rittenhouse, ... Antimicrobial agents and chemotherapy 46 (11), 3343-3347, 2002 | 151 | 2002 |
| Discovery of aminopyridine-based inhibitors of bacterial enoyl-ACP reductase (FabI) WH Miller, MA Seefeld, KA Newlander, IN Uzinskas, WJ Burgess, ... Journal of medicinal chemistry 45 (15), 3246-3256, 2002 | 149 | 2002 |
| 1, 4-Disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI) DA Heerding, G Chan, WE DeWolf Jr, AP Fosberry, CA Janson, ... Bioorganic & medicinal chemistry letters 11 (16), 2061-2065, 2001 | 148 | 2001 |
| Characterization of Streptococcus pneumoniae enoyl-(acyl-carrier protein) reductase (FabK) H Marrakchi, WE DeWolf Jr, C Quinn, J West, BJ Polizzi, CY So, ... Biochemical Journal 370 (3), 1055-1062, 2003 | 147 | 2003 |
| Identification of a series of tricyclic natural products as potent broad-spectrum inhibitors of metallo-β-lactamases DJ Payne, JA Hueso-Rodríguez, H Boyd, NO Concha, CA Janson, ... Antimicrobial agents and chemotherapy 46 (6), 1880-1886, 2002 | 140 | 2002 |
