| Mapping the conformational wave of acetylcholine receptor channel gating C Grosman, M Zhou, A Auerbach Nature 403 (6771), 773-776, 2000 | 385 | 2000 |
| Probing ion-channel pores one proton at a time GD Cymes, Y Ni, C Grosman Nature 438 (7070), 975-980, 2005 | 180 | 2005 |
| The extracellular linker of muscle acetylcholine receptor channels is a gating control element C Grosman, FN Salamone, SM Sine, A Auerbach The Journal of general physiology 116 (3), 327-340, 2000 | 145 | 2000 |
| The dissociation of acetylcholine from open nicotinic receptor channels C Grosman, A Auerbach Proceedings of the National Academy of Sciences 98 (24), 14102-14107, 2001 | 112 | 2001 |
| Structure of the transition state of gating in the acetylcholine receptor channel pore: a φ-value analysis GD Cymes, C Grosman, A Auerbach Biochemistry 41 (17), 5548-5555, 2002 | 105 | 2002 |
| Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals G Gonzalez-Gutierrez, T Lukk, V Agarwal, D Papke, SK Nair, C Grosman Proceedings of the National Academy of Sciences 109 (16), 6331-6336, 2012 | 90 | 2012 |
| Kinetic, mechanistic, and structural aspects of unliganded gating of acetylcholine receptor channels: A single-channel study of second transmembrane segment 12′ mutants C Grosman, A Auerbach The Journal of general physiology 115 (5), 621-635, 2000 | 90 | 2000 |
| Asymmetric and independent contribution of the second transmembrane segment 12′ residues to diliganded gating of acetylcholine receptor channels: a single-channel study with … C Grosman, A Auerbach The Journal of general physiology 115 (5), 637-651, 2000 | 84 | 2000 |
| Bridging the gap between structural models of nicotinic receptor superfamily ion channels and their corresponding functional states G Gonzalez-Gutierrez, C Grosman Journal of molecular biology 403 (5), 693-705, 2010 | 68 | 2010 |
| Pore-opening mechanism of the nicotinic acetylcholine receptor evinced by proton transfer GD Cymes, C Grosman Nature structural & molecular biology 15 (4), 389-396, 2008 | 61 | 2008 |
| Electrodiffusional ATP movement through the cystic fibrosis transmembrane conductance regulator HF Cantiello, GR Jackson Jr, CF Grosman, AG Prat, SC Borkan, Y Wang, ... American Journal of Physiology-Cell Physiology 274 (3), C799-C809, 1998 | 61 | 1998 |
| Gating of the proton-gated ion channel from Gloeobacter violaceus at pH 4 as revealed by X-ray crystallography G Gonzalez-Gutierrez, LG Cuello, SK Nair, C Grosman Proceedings of the National Academy of Sciences 110 (46), 18716-18721, 2013 | 53 | 2013 |
| Desensitization of neurotransmitter‐gated ion channels during high‐frequency stimulation: a comparative study of Cys‐loop, AMPA and purinergic receptors D Papke, G Gonzalez‐Gutierrez, C Grosman The Journal of physiology 589 (7), 1571-1585, 2011 | 47 | 2011 |
| The role of intracellular linkers in gating and desensitization of human pentameric ligand-gated ion channels D Papke, C Grosman Journal of Neuroscience 34 (21), 7238-7252, 2014 | 45 | 2014 |
| Block of muscle nicotinic receptors by choline suggests that the activation and desensitization gates act as distinct molecular entities Y Purohit, C Grosman The Journal of general physiology 127 (6), 703-717, 2006 | 43 | 2006 |
| Desensitization contributes to the synaptic response of gain-of-function mutants of the muscle nicotinic receptor S Elenes, Y Ni, GD Cymes, C Grosman The Journal of general physiology 128 (5), 615-627, 2006 | 36 | 2006 |
| The unanticipated complexity of the selectivity-filter glutamates of nicotinic receptors GD Cymes, C Grosman Nature chemical biology 8 (12), 975-981, 2012 | 34 | 2012 |
| Estimating binding affinities of the nicotinic receptor for low-efficacy ligands using mixtures of agonists and two-dimensional concentration–response relationships Y Purohit, C Grosman The Journal of general physiology 127 (6), 719-735, 2006 | 32 | 2006 |
| Tunable pKa values and the basis of opposite charge selectivities in nicotinic-type receptors GD Cymes, C Grosman Nature 474 (7352), 526-530, 2011 | 29 | 2011 |
| Free-energy landscapes of ion-channel gating are malleable: changes in the number of bound ligands are accompanied by changes in the location of the transition state in … C Grosman Biochemistry 42 (50), 14977-14987, 2003 | 29 | 2003 |
