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Austin E. Y. T. Lefebvre, Ph.D.
Austin E. Y. T. Lefebvre, Ph.D.
Data Scientist at Calico Life Sciences
Verified email at calicolabs.com - Homepage
Title
Cited by
Cited by
Year
Transcriptional diversity and bioenergetic shift in human breast cancer metastasis revealed by single-cell RNA sequencing
RT Davis, K Blake, D Ma, MBI Gabra, GA Hernandez, AT Phung, Y Yang, ...
Nature cell biology 22 (3), 310-320, 2020
2122020
Collagen density modulates triple-negative breast cancer cell metabolism through adhesion-mediated contractility
EJ Mah, AEYT Lefebvre, GE McGahey, AF Yee, MA Digman
Scientific reports 8 (1), 17094, 2018
682018
Automated segmentation and tracking of mitochondria in live-cell time-lapse images
AEYT Lefebvre, D Ma, K Kessenbrock, DA Lawson, MA Digman
Nature methods 18 (9), 1091-1102, 2021
612021
LKB1 promotes metabolic flexibility in response to energy stress
SJ Parker, RU Svensson, AS Divakaruni, AE Lefebvre, AN Murphy, ...
Metabolic engineering 43, 208-217, 2017
532017
Disruption of the circadian clock drives Apc loss of heterozygosity to accelerate colorectal cancer
SK Chun, BM Fortin, RC Fellows, AN Habowski, A Verlande, WA Song, ...
Science advances 8 (31), eabo2389, 2022
362022
Patient-derived xenograft culture-transplant system for investigation of human breast cancer metastasis
D Ma, GA Hernandez, AEYT Lefebvre, H Alshetaiwi, K Blake, KR Dave, ...
Communications biology 4 (1), 1268, 2021
62021
Microenvironmental stiffness induces metabolic reprogramming in glioblastoma
A Sohrabi, AEYT Lefebvre, MJ Harrison, MC Condro, TM Sanazzaro, ...
Cell reports 42 (10), 2023
42023
The actin binding protein profilin 1 is critical for mitochondria function
TA Read, BA Cisterna, K Skruber, S Ahmadieh, HL Lindamood, JA Vitriol, ...
bioRxiv, 2023
42023
The microenvironment dictates glycocalyx construction and immune surveillance
KM Tharp, S Park, GA Timblin, AL Richards, JA Berg, NM Twells, ...
Research Square, 2023
12023
Nellie: Automated organelle segmentation, tracking, and hierarchical feature extraction in 2D/3D live-cell microscopy
AEYT Lefebvre, G Sturm, TY Lin, E Stoops, MP Lopez, ...
arXiv preprint arXiv:2403.13214, 2024
2024
Metabolic profiling and tracking phenotypic changes in mitochondria in cancer cells with mitometer and the phasor approach to FLIM
MA Digman, G Tedeschi, L Scipioni, AE Lefebvre, F Palomba
Biophysical Journal 123 (3), 36a, 2024
2024
BIOMIMETIC HYALURONIC ACID-BASED HYDROGELS TO INVESTIGATE ROLE OF TUMOR BIOPHYSICAL PROPERTIES ON GLIOBLASTOMA (GBM) PROGRESSION
A Sohrabi, J Liang, A Lefebvre, M Condro, H Kornblum, M Digman, ...
TISSUE ENGINEERING PART A 28, S517-S517, 2022
2022
Effects Of Matrix Stiffness On Glioblastoma Metabolism
SK Seidlits, A Sohrabi, A Lefebvre, M Condro, HI Kornblum, MA Digman
2022
Tracking Motility and Morphology of Individual Mitochondria Reveals Large Heterogeneities in Breast Cancer Subtypes
AEYT Lefebvre, D Ma, K Kessenbrock, DA Lawson, MA Digman
Biophysical Journal 120 (3), 194a, 2021
2021
The Phenotypic Investigation of Mitochondria in Cancer
A Lefebvre
University of California, Irvine, 2021
2021
Non-destructively Analyzing the Metabolic Dysregulation of Invasive Cancer Cells on an Intracellular Scale
AEYT Lefebvre, FA Adame, M Liu, MA Digman
Biophysical Journal 118 (3), 307a, 2020
2020
The Phasor FLIM Analysis Monitors Metabolic Changes at the Leading Edge in Response to Rac Photo-Activation and Mitochondrial Transport in MDA MB231 Cells
MA Digman, A Lefebvre, F Adame, E Fong
Biophysical Journal 116 (3), 442a, 2019
2019
A Non-Invasive Metabolic Investigation of Breast Cancer Invasion
AEYT Lefebvre, FA Adame, MA Digman
Biophysical Journal 116 (3), 550a, 2019
2019
Cancer Cells' Situational Awareness: The Mechanosensing Metabolic Shift of Invasive Breast Cells.
AE Lefebvre, EJ Mah, GE McGahey, AF Yee, MA Digman
MOLECULAR BIOLOGY OF THE CELL 29 (26), 2018
2018
TRACKING MITOCHONDRIA REVEALS METABOLIC AND DYNAMIC HETEROGENEITY IN BREAST CANCERS
AEYT Lefebvre
2021 Annual Meeting, 0
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Articles 1–20