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Kristin Jansen Labby
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Year
Mechanisms of resistance to aminoglycoside antibiotics: overview and perspectives
S Garneau-Tsodikova, KJ Labby
Medchemcomm 7 (1), 11-27, 2016
5142016
Target-and mechanism-based therapeutics for neurodegenerative diseases: strength in numbers
PC Trippier, K Jansen Labby, DD Hawker, JJ Mataka, RB Silverman
Journal of medicinal chemistry 56 (8), 3121-3147, 2013
1642013
Strategies to overcome the action of aminoglycoside-modifying enzymes for treating resistant bacterial infections
KJ Labby, S Garneau-Tsodikova
Future medicinal chemistry 5 (11), 1285-1309, 2013
1272013
Interrupted adenylation domains: unique bifunctional enzymes involved in nonribosomal peptide biosynthesis
KJ Labby, SG Watsula, S Garneau-Tsodikova
Natural product reports 32 (5), 641-653, 2015
732015
Molecular mechanism for isoform-selective inhibition of acyl protein thioesterases 1 and 2 (APT1 and APT2)
SJ Won, D Davda, KJ Labby, SY Hwang, R Pricer, JD Majmudar, ...
ACS chemical biology 11 (12), 3374-3382, 2016
722016
Harnessing redox cross-reactivity to profile distinct cysteine modifications
JD Majmudar, AM Konopko, KJ Labby, CTMB Tom, JE Crellin, A Prakash, ...
Journal of the American Chemical Society 138 (6), 1852-1859, 2016
562016
Intramolecular hydrogen bonding: a potential strategy for more bioavailable inhibitors of neuronal nitric oxide synthase
KJ Labby, F Xue, JM Kraus, H Ji, J Mataka, H Li, P Martásek, LJ Roman, ...
Bioorganic & medicinal chemistry 20 (7), 2435-2443, 2012
512012
Synthesis and evaluation of hetero-and homodimers of ribosome-targeting antibiotics: antimicrobial activity, in vitro inhibition of translation, and drug resistance
Y Berkov-Zrihen, KD Green, KJ Labby, M Feldman, S Garneau-Tsodikova, ...
Journal of medicinal chemistry 56 (13), 5613-5625, 2013
442013
Selective monocationic inhibitors of neuronal nitric oxide synthase. Binding mode insights from molecular dynamics simulations
H Huang, H Ji, H Li, Q Jing, KJ Labby, P Martásek, LJ Roman, TL Poulos, ...
Journal of the American Chemical Society 134 (28), 11559-11572, 2012
362012
Mechanisms of resistance to aminoglycoside antibiotics: overview and perspectives. Medchemcomm 7: 11–27
S Garneau-Tsodikova, KJ Labby
222016
Redesign of substrate specificity and identification of the aminoglycoside binding residues of Eis from Mycobacterium tuberculosis
BC Jennings, KJ Labby, KD Green, S Garneau-Tsodikova
Biochemistry 52 (30), 5125-5132, 2013
202013
Improved synthesis of chiral pyrrolidine inhibitors and their binding properties to neuronal nitric oxide synthase
F Xue, JM Kraus, KJ Labby, H Ji, J Mataka, G Xia, H Li, SL Delker, ...
Journal of medicinal chemistry 54 (18), 6399-6403, 2011
192011
Cyclopropyl-and methyl-containing inhibitors of neuronal nitric oxide synthase
H Li, F Xue, JM Kraus II, H Ji, KJ Labby, J Mataka, SL Delker, P Martásek, ...
Bioorganic & medicinal chemistry 21 (5), 1333-1343, 2013
172013
Chemoselective ratiometric imaging of protein S-sulfenylation
CTMB Tom, JE Crellin, HF Motiwala, MB Stone, D Davda, W Walker, ...
Chemical communications 53 (53), 7385-7388, 2017
162017
Enzymatic and cryoreduction EPR studies of the hydroxylation of methylated N ω-hydroxy-L-arginine analogues by nitric oxide synthase from Geobacillus stearothermophilus
R Davydov, KJ Labby, SE Chobot, DA Lukoyanov, BR Crane, ...
Biochemistry 53 (41), 6511-6519, 2014
162014
Methylated Nω-Hydroxy-l-arginine Analogues as Mechanistic Probes for the Second Step of the Nitric Oxide Synthase-Catalyzed Reaction
K Jansen Labby, H Li, LJ Roman, P Martásek, TL Poulos, RB Silverman
Biochemistry 52 (18), 3062-3073, 2013
162013
Strategies to overcome the action of aminoglycoside-modifying enzymes for treating resistant bacterial infections. Future Med Chem 5: 1285–1309
KJ Labby, S Garneau-Tsodikova
112013
Mechanisms of resistance to aminoglycoside antibiotics: Overview and perspectives. Medchemcomm. 2016; 7 (1): 11–27
S Garneau-Tsodikova, KJ Labby
PubMed Abstract| Publisher Full Text| Free Full Text| F1000 Recommendation, 0
11
Contextualizing chemistry in art and archaeology: inspiration for instructors
American Chemical Society
American Chemical Society, 2021
42021
The Chemistry of Art and Artifacts: A Sophomore-Level, Thematic Chemical Instrumentation Course
KJ Labby
Contextualizing Chemistry in Art and Archaeology: Inspiration for …, 2021
22021
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Articles 1–20