| A protective role for protease-activated receptors in the airways TM Cocks, B Fong, JM Chow, GP Anderson, AG Frauman, RG Goldie, ... Nature 398 (6723), 156-160, 1999 | 427 | 1999 |
| Protease-activated receptors 1 and 4 mediate thrombin signaling in endothelial cells H Kataoka, JR Hamilton, DD McKemy, E Camerer, YW Zheng, A Cheng, ... Blood 102 (9), 3224-3231, 2003 | 224 | 2003 |
| Protection against thrombosis in mice lacking PAR3 EJ Weiss, JR Hamilton, KE Lease, SR Coughlin Blood, The Journal of the American Society of Hematology 100 (9), 3240-3244, 2002 | 222 | 2002 |
| Par4 is required for platelet thrombus propagation but not fibrin generation in a mouse model of thrombosis ER Vandendries, JR Hamilton, SR Coughlin, B Furie, BC Furie Proceedings of the National Academy of Sciences 104 (1), 288-292, 2007 | 196 | 2007 |
| Increased expression of protease-activated receptor-2 (PAR2) and PAR4 in human coronary artery by inflammatory stimuli unveils endothelium-dependent relaxations to PAR2 and … JR Hamilton, AG Frauman, TM Cocks Circulation research 89 (1), 92-98, 2001 | 189 | 2001 |
| Identification of a fibrin-independent platelet contractile mechanism regulating primary hemostasis and thrombus growth A Ono, E Westein, S Hsiao, WS Nesbitt, JR Hamilton, SM Schoenwaelder, ... Blood, The Journal of the American Society of Hematology 112 (1), 90-99, 2008 | 152 | 2008 |
| Protease-activated receptor-2 activation induces acute lung inflammation by neuropeptide-dependent mechanisms X Su, E Camerer, JR Hamilton, SR Coughlin, MA Matthay The Journal of Immunology 175 (4), 2598-2605, 2005 | 121 | 2005 |
| Pathologic shear triggers shedding of vascular receptors: a novel mechanism for down-regulation of platelet glycoprotein VI in stenosed coronary vessels M Al-Tamimi, CW Tan, J Qiao, GJ Pennings, A Javadzadegan, ASC Yong, ... Blood, The Journal of the American Society of Hematology 119 (18), 4311-4320, 2012 | 119 | 2012 |
| Impaired hemostasis and protection against thrombosis in protease‐activated receptor 4‐deficient mice is due to lack of thrombin signaling in platelets JR Hamilton, I Cornelissen, SR Coughlin Journal of thrombosis and haemostasis 2 (8), 1429-1435, 2004 | 119 | 2004 |
| Atypical protease-activated receptor mediates endothelium-dependent relaxation of human coronary arteries JR Hamilton, PB Nguyen, TM Cocks Circulation research 82 (12), 1306-1311, 1998 | 93 | 1998 |
| The class II PI 3-kinase, PI3KC2α, links platelet internal membrane structure to shear-dependent adhesive function JK Mountford, C Petitjean, HWK Putra, JA McCafferty, NM Setiabakti, ... Nature communications 6 (1), 6535, 2015 | 85 | 2015 |
| Structure and function of the open canalicular system–the platelet’s specialized internal membrane network MV Selvadurai, JR Hamilton Platelets 29 (4), 319-325, 2018 | 82 | 2018 |
| Evaluation of protease‐activated receptor 2 in murine models of arthritis N Busso, M Frasnelli, R Feifel, B Cenni, M Steinhoff, J Hamilton, A So Arthritis & Rheumatism 56 (1), 101-107, 2007 | 81 | 2007 |
| Protease-activated receptor (PAR) 1 but not PAR2 or PAR4 mediates endothelium-dependent relaxation to thrombin and trypsin in human pulmonary arteries JR Hamilton, JD Moffatt, AG Frauman, TM Cocks Journal of cardiovascular pharmacology 38 (1), 108-119, 2001 | 79 | 2001 |
| Platelet and erythrocyte sources of S1P are redundant for vascular development and homeostasis, but both rendered essential after plasma S1P depletion in anaphylactic shock SL Gazit, B Mariko, P Thérond, B Decouture, Y Xiong, L Couty, P Bonnin, ... Circulation research 119 (8), e110-e126, 2016 | 77 | 2016 |
| Thrombin-induced reactive oxygen species generation in platelets: A novel role for protease-activated receptor 4 and GPIbα N Carrim, JF Arthur, JR Hamilton, EE Gardiner, RK Andrews, N Moran, ... Redox biology 6, 640-647, 2015 | 74 | 2015 |
| Challenges and opportunities in protease-activated receptor drug development JR Hamilton, JA Trejo Annual review of pharmacology and toxicology 57, 349-373, 2017 | 64 | 2017 |
| Protease‐activated receptor 4: from structure to function and back again SL French, JR Hamilton British journal of pharmacology 173 (20), 2952-2965, 2016 | 64 | 2016 |
| Inhibition of protease‐activated receptor 4 impairs platelet procoagulant activity during thrombus formation in human blood SL French, JF Arthur, H Lee, WS Nesbitt, RK Andrews, EE Gardiner, ... Journal of Thrombosis and Haemostasis 14 (8), 1642-1654, 2016 | 60 | 2016 |
| Heterogeneous mechanisms of endothelium‐dependent relaxation for thrombin and peptide activators of protease‐activated receptor‐1 in porcine isolated coronary artery JR Hamilton, TM Cocks British journal of pharmacology 130 (1), 181-188, 2000 | 60 | 2000 |
