| Artificial oxygen carriers, hemoglobin vesicles and albumin− hemes, based on bioconjugate chemistry E Tsuchida, K Sou, A Nakagawa, H Sakai, T Komatsu, K Kobayashi Bioconjugate chemistry 20 (8), 1419-1440, 2009 | 187 | 2009 |
| Sulfide catabolism ameliorates hypoxic brain injury E Marutani, M Morita, S Hirai, S Kai, RMH Grange, Y Miyazaki, ... Nature communications 12 (1), 3108, 2021 | 80 | 2021 |
| O2 and CO binding properties of artificial hemoproteins formed by complexing iron protoporphyrin IX with human serum albumin mutants T Komatsu, N Ohmichi, A Nakagawa, PA Zunszain, S Curry, E Tsuchida Journal of the American Chemical Society 127 (45), 15933-15942, 2005 | 65 | 2005 |
| Self‐organized lipid‐porphyrin bilayer membranes in vesicular form: nanostructure, photophysical properties, and dioxygen coordination T Komatsu, M Moritake, A Nakagawa, E Tsuchida Chemistry–A European Journal 8 (23), 5469-5480, 2002 | 64 | 2002 |
| Identification of a small molecule that increases hemoglobin oxygen affinity and reduces SS erythrocyte sickling A Nakagawa, FE Lui, D Wassaf, R Yefidoff-Freedman, D Casalena, ... ACS chemical biology 9 (10), 2318-2325, 2014 | 63 | 2014 |
| Human serum albumin bearing covalently attached iron (II) porphyrins as O2-coordination sites RM Wang, T Komatsu, A Nakagawa, E Tsuchida Bioconjugate chemistry 16 (1), 23-26, 2005 | 42 | 2005 |
| Human serum albumin incorporating synthetic heme: red blood cell substitute without hypertension by nitric oxide scavenging E Tsuchida, T Komatsu, Y Matsukawa, A Nakagawa, H Sakai, ... Journal of Biomedical Materials Research Part A: An Official Journal of The …, 2003 | 40 | 2003 |
| Genetic engineering of the heme pocket in human serum albumin: modulation of O2 binding of iron protoporphyrin IX by variation of distal amino acids T Komatsu, A Nakagawa, PA Zunszain, S Curry, E Tsuchida Journal of the American Chemical Society 129 (36), 11286-11295, 2007 | 37 | 2007 |
| Adverse effects of hemorrhagic shock resuscitation with stored blood are ameliorated by inhaled nitric oxide in lambs DM Baron, A Beloiartsev, A Nakagawa, T Martyn, CP Stowell, R Malhotra, ... Critical care medicine 41 (11), 2492-2501, 2013 | 32 | 2013 |
| A triazole disulfide compound increases the affinity of hemoglobin for oxygen and reduces the sickling of human sickle cells A Nakagawa, M Ferrari, G Schleifer, MK Cooper, C Liu, B Yu, L Berra, ... Molecular pharmaceutics 15 (5), 1954-1963, 2018 | 31 | 2018 |
| Poly (ethylene glycol)-conjugated human serum albumin including iron porphyrins: surface modification improves the O2-transporting ability Y Huang, T Komatsu, RM Wang, A Nakagawa, E Tsuchida Bioconjugate chemistry 17 (2), 393-398, 2006 | 30 | 2006 |
| Pulmonary phototherapy for treating carbon monoxide poisoning L Zazzeron, C Liu, W Franco, A Nakagawa, WA Farinelli, DB Bloch, ... American Journal of Respiratory and Critical Care Medicine 192 (10), 1191-1199, 2015 | 26 | 2015 |
| Structural and mutagenic approach to create human serum albumin-based oxygen carrier and photosensitizer T Komatsu, A Nakagawa, X Qu Drug metabolism and pharmacokinetics 24 (4), 287-299, 2009 | 22 | 2009 |
| Albumin clusters: structurally defined protein tetramer and oxygen carrier including thirty-two iron (II) porphyrins T Komatsu, Y Oguro, A Nakagawa, E Tsuchida Biomacromolecules 6 (6), 3397-3403, 2005 | 22 | 2005 |
| Targeting βCys93 in hemoglobin S with an antisickling agent possessing dual allosteric and antioxidant effects T Kassa, M Brad Strader, A Nakagawa, WM Zapol, AI Alayash Metallomics 9 (9), 1260-1270, 2017 | 19 | 2017 |
| The role of an amino acid triad at the entrance of the heme pocket in human serum albumin for O 2 and CO binding to iron protoporphyrin IX T Komatsu, A Nakagawa, S Curry, E Tsuchida, K Murata, N Nakamura, ... Organic & biomolecular chemistry 7 (18), 3836-3841, 2009 | 19 | 2009 |
| Compatibility in vitro of albumin‐heme (O2 carrier) with blood cell components Y Huang, T Komatsu, A Nakagawa, E Tsuchida, S Kobayashi Journal of Biomedical Materials Research Part A: An Official Journal of The …, 2003 | 19 | 2003 |
| Hypoxia ameliorates brain hyperoxia and NAD+ deficiency in a murine model of Leigh syndrome RMH Grange, R Sharma, H Shah, B Reinstadler, O Goldberger, ... Molecular genetics and metabolism 133 (1), 83-93, 2021 | 18 | 2021 |
| Induced long-range attractive potentials of human serum albumin by ligand binding T Sato, T Komatsu, A Nakagawa, E Tsuchida Physical review letters 98 (20), 208101, 2007 | 18 | 2007 |
| O2 Binding to Human Serum Albumin Incorporating Iron Porphyrin with a Covalently Linked Methyl-l-Histidine Isomer A Nakagawa, T Komatsu, M Iizuka, E Tsuchida Bioconjugate chemistry 19 (3), 581-584, 2008 | 16 | 2008 |
